2023 News Briefs - International Neuromodulation Society

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Company Initiates Early Feasibility Study for Non-Invasive Neuromodulation Device in ALS Patients

September 15, 2023 - PathMaker Neurosystems has initiated an early feasibility study to assess its non-invasive neuromodulation device, MyoRegulator, in patients with amyotrophic lateral sclerosis (ALS). The device, designed to suppress motor neuron hyperexcitability via skin pads, aims to provide an alternative treatment option for ALS, a progressive neurodegenerative disease with limited pharmaceutical interventions. (Source: Medical Device Network)

Deep Brain Stimulation During Sleep Enhances Memory Consolidation in Epilepsy Patients

September 14, 2023 - A study published in Nature Neuroscience reveals that targeted deep-brain stimulation during a specific sleep stage improves memory consolidation in epilepsy patients. Researchers used a closed-loop system to synchronize brain activity between the hippocampus and cortex using electrical pulses during sleep, leading to enhanced memory performance. This study offers insights into memory mechanisms and potential applications for memory disorders like Alzheimer's. (Source: AJMC)

Thin-Film Neural Electrodes for Enhanced Brain Monitoring and Stimulation

September 14, 2023 - Researchers at Tokyo Institute of Technology have developed flexible thin-film neural electrodes designed to match the mechanical properties of brain tissue, improving electrocorticography (ECoG) recordings and targeted neural stimulation. These electrodes, made from polystyrene-block-polybutadiene-block-polystyrene (SBS) and gold nanoink, conform accurately to the brain's irregular ridges. Experiments on epilepsy rat models demonstrated their potential for precise neural measurements, visualization of seizure activity, and stimulation of various brain regions without causing inflammation or adverse effects. (Source: Eureka! Alert)

Study Reveals Lack of Knowledge Among Umm Al-Qura University Medical Students About Neuromodulation Devices

September 14, 2023 - A study conducted among medical students at Umm Al-Qura University in Saudi Arabia has highlighted a significant lack of knowledge regarding neuromodulation (NM) devices. The research aimed to assess the knowledge and perception of NM devices among undergraduate medical students and found that both pre-clinical and clinical-year students exhibited insufficient knowledge. The study suggests the need for comprehensive education on NM devices to ensure optimal patient care and early referrals for treatment. (Source: Cureus)

Study Finds Device Shows Promise in Relieving Symptoms for Teens with Painful GI Disorders

September 13, 2023 - NeurAxis, formerly known as Innovative Health Solutions, has conducted a study demonstrating that its IB-Stim neuromodulation device can effectively alleviate pain in teenagers with disorders of the gut-brain interaction (DGBIs) such as irritable bowel syndrome (IBS). The study involved 31 patients aged 11 to 18 and showed significant reductions in abdominal pain, nausea, functional disability, and somatization after four weeks of treatment with IB-Stim. While self-reported quality of life scores didn't show a statistically significant change, parents observed marked improvements in their children's physical and psychosocial function. (Source: Fierce Biotech)

Focused Ultrasound Opens Blood-Brain Barrier for Potential Alzheimer's Treatment

September 13, 2023 - Two new studies by researchers from Columbia University have demonstrated the use of non-invasive focused ultrasound (FUS) to open the blood-brain barrier (BBB), potentially offering a non-invasive method to treat neurodegenerative diseases like Alzheimer's. In the first study, FUS and microbubbles allowed the delivery of CRISPR gene-editing technology to mouse neurons with over 25% editing efficiency, suggesting potential gene corrections for Alzheimer's disease. In the second study, FUS alone triggered an immune response in mice's brains, reducing beta-amyloid and tau loads, two proteins linked to Alzheimer's, and improving working memory. (Source: New Atlas)

Abbott Issues Urgent Medical Device Correction for Over 197,000 Neuromodulation Systems Following Class I FDA Rating

September 12, 2023 - Abbott has issued an urgent medical device correction for over 197,000 of its implanted neuromodulation systems, which includes spinal cord stimulators and a deep brain stimulator. The correction comes after reports that some devices failed to restart after exiting the "MRI mode," meant to temporarily disable therapy during imaging scans. The issue, which has received a Class I rating from the FDA, is related to Bluetooth pairing problems between the implantable pulse generator and the Patient Controller app, either due to user actions or software updates. Abbott has updated device instructions and app notifications to address the problem, and additional surgeries have been required in about half of the reported cases. The company didn't disclose the exact number of complaints or whether any injuries occurred but noted an incidence rate of around 0.06% of all distributed devices. (Source: Fierce Biotech)

AI-Powered Brain Implant Restores Speech to Paralyzed Stroke Survivor

September 10, 2023 - After nearly two decades of being unable to speak due to a brain stem stroke, Ann Johnson becomes the first patient to successfully use an AI-driven brain implant that decodes her brain signals, allowing her to communicate through a computer-generated avatar that synthesizes speech and facial expressions. Researchers at the University of California San Francisco and the University of California Berkeley achieved this breakthrough. (Source: Business Insider)

Article Addresses Unlocking Health Benefits through Vagus Nerve Stimulation

September 10, 2023 - The article highlights the therapeutic potential of vagus nerve stimulation in addressing diverse health issues like depression, obesity, alcoholism, and inflammation. Various methods, such as cold exposure and controlled breathing, are discussed as means to stimulate the vagus nerve. Research explores its impact on conditions like epilepsy, arthritis, Crohn's disease, and obesity. (Source: Newstalk)

Article Addresses Transcranial Magnetic Stimulation as a Growing Therapy for Depression and Beyond

September 10, 2023 - Transcranial magnetic stimulation (TMS) is gaining traction as a treatment for depression, with promising results in clinical trials. Additionally, research explores its potential effectiveness in addressing conditions like OCD, addiction disorders, chronic pain, autism, and ADHD. Challenges include the need for daily clinic visits and potential limitations in Medicare funding for maintenance treatments. (Source: PsyPost)

Study Suggests Deep Brain Stimulation Enhances Memory Consolidation During Sleep in Epilepsy Patients

September 8, 2023 - A study published in Nature Neuroscience suggests that targeted deep-brain stimulation during specific sleep phases can improve memory consolidation in epilepsy patients. The research reveals the interaction between the memory hub and the cortex and opens possibilities for memory enhancement in individuals with disorders like Alzheimer's disease. (Source: NeurologyLive)

Clinical Review Discusses Use of Neuromodulation Techniques During Pregnancy and Lactation

September 8, 2023 - This clinical review explores the management of epilepsy in pregnant and lactating women, particularly emphasizing the role of neuromodulation techniques. It discusses the safety and effectiveness of treatments like vagal nerve stimulation, responsive neurostimulation, and deep brain stimulation in this population, alongside antiseizure medications. (Source: BMJ)

Transcranial Stimulation Study Shows Promise in Treating Consciousness Disorders After Brain Injury

September 6, 2023 - Published in the European Journal of Neurology, an international study led by the University of Liège has tested transcranial direct current stimulation (tDCS) on patients with consciousness disorders following severe brain injuries and reports promising results at the three-month follow-up. (Source: EurekaAlert!)

Six U.S. Patients Receive Brain-Computer Interface Implant in Company's Feasibility Study

September 6, 2023 - Synchron has successfully implanted its brain-computer interface device in six patients as part of its U.S.-based feasibility study. The device aims to restore functioning for patients with severe paralysis. Results from the study are expected to be available next year. (Source: MedTech Dive)

Company Receives CE Mark for Closed-Loop Spinal Cord Stimulator

September 6, 2023 - Medtronic has been granted a CE mark for its Inceptiv closed-loop rechargeable spinal cord stimulator (SCS). The device incorporates closed-loop therapy with evoked compound action potentials (ECAPs) to continuously sense the body’s neural response to stimulation and automatically adjust spinal cord stimulation levels in real-time, providing consistent therapy for patients during various activities. The system offers full-body MRI access and is expected to be available in Europe soon. (Source: Medical Device and Diagnostic Industry)

Brain Stimulation Aids Stroke Patients in Small Trial

September 5, 2023 - A small clinical trial conducted by researchers at the Cleveland Clinic used deep brain stimulation (DBS) in combination with physical therapy to improve upper limb function in stroke patients. The trial involved 12 participants with moderate to severe upper limb impairment post-stroke. Results showed that the DBS and physical therapy combination was safe and improved motor function in nine of the participants, with better outcomes in those with retained motor function in the hand. (Source: National Institutes of Health)

Meta-Analyses Suggest Intrathecal Drug Delivery Effective for Managing Cancer-Related Pain

September 5, 2023 - Recent systematic reviews and meta-analyses have provided evidence that intrathecal drug delivery (IDD) systems are an effective approach for managing cancer-related pain and patients may benefit from its increased application. The reviews show a significant reduction in pain intensity and opioid consumption among cancer patients who received IDD, with minor complications reported, suggesting the potential for safer and more efficient pain relief. (Source: NeuroNews)

Research Review Addresses the State of Preoperative Functional MRI Enhances Brain Tumor Surgery Outcomes and Suggests Future Directions

September 5, 2023 - Preoperative functional MRI (fMRI) plays a crucial role in improving surgical outcomes for patients with brain tumors. This technique aids in planning surgical approaches, preserving essential brain functions, and reducing adverse events during surgery. This review suggests that while the clinical benefits of fMRI in neuro-oncology are well-established, ongoing research would benefit from focusing on addressing challenges, such as neurovascular uncoupling and harnessing artificial intelligence. (Source: RSNA)

Company Acquires Bioinduction and Aims to Accelerate Development and Breadth of Neurostim Technology Portfolio

September 5, 2023 - Amber Therapeutics, a startup spin out of the University of Oxford, has acquired bioinduction, a UK-based company known for its Picostim DyNeuMo platform. This platform was initially designed for deep brain stimulation in Parkinson’s disease and has been integrated into neuromodulation systems like Amber’s. The company aims to accelerate its development and build a broader neurostim technology portfolio. (Source: Fierce Biotech)

Article Investigates Vagus Nerve Stimulation's Effect on Aldosterone Levels

September 4, 2023 - A recent study examined the impact of acute transcutaneous vagus nerve stimulation (tVNS) on serum aldosterone levels, a mineralocorticoid hormone linked to cardiovascular injuries and hypertension. The study found that while tVNS reduced aldosterone levels in younger and older adults, the difference was not significant enough to draw relevant conclusions. Aldosterone levels were influenced by age and sex, as well, irrespective of tVNS. (Source: News Medical)

Study Reveals Insights About Brain's Locomotion Control Center Through Nerve Stimulation

September 4, 2023 - Researchers uncovered key mechanisms in the brain that control the initiation of movement. The mesencephalic locomotor region (MLR) found in various vertebrates plays a crucial role in initiating movements like walking, flying, and swimming. Using zebrafish larvae brains, the study observed and mapped the neural circuits responsible for triggering forward motion and found that stimulation intensity correlates with vigor of movement. This discovery holds potential for understanding and addressing motor deficiencies, particularly in conditions like Parkinson’s disease (Source: Neuroscience News)

Article Addresses Patient's Experience with Deep Brain Stimulation for Essential Tremor 

September 1, 2023 - A patient underwent deep brain stimulation (DBS) to alleviate the debilitating effects of essential tremor which had affected her for 37 years. After the procedure, the patient experienced significant improvements in hand function, enabling better performance in everyday tasks and some improvement in speech. (Source: Froedtert)

Case Study Found Intrathecal Baclofen Pump Provided Significant Pain Relief for Patient with Chronic Spastic Hemiplegia Following Stroke

September 1, 2023 - A 62-year-old woman who had been suffering from painful spasticity for 15 years following an ischemic stroke underwent intrathecal baclofen infusion pump (IBIP) therapy, achieving significant pain relief and partial spasticity improvement. (Source: Cureus)

Study Suggests Brain Stimulation Through Electrodes Could Enhance Mathematical Learning

August 31, 2023 - Researchers from multiple universities, including Surrey, Oxford, and Radboud, have explored the potential of neurostimulation using high-frequency random noise stimulation (tRNS) delivered through electrodes on the scalp to improve mathematical skills, particularly in individuals who struggle with math. The study found that this neurostimulation could enhance learning outcomes, particularly for those with lower brain excitability. (Source: The Independent)

Study Finds Vagus Nerve Stimulation Reduces Serum Aldosterone Levels in Women as They Age

August 30, 2023 - A recent randomized study examined the effects of transcutaneous vagus nerve stimulation (tVNS) on serum aldosterone levels in healthy participants of different age groups. While aldosterone levels decreased post-stimulation in both younger and older participants, the study revealed a significant interaction between sex and age, with younger women having the highest mineralocorticoid levels and older females showing the lowest. (Source: Nature)

Two-Year Data Confirms Long-Term Efficacy of Company's SCS Therapy for Painful Diabetic Neuropathy

August 30, 2023 - Nevro Corporation has published two-year data from the SENZA painful diabetic neuropathy (PDN) trial, revealing the long-term effectiveness of high-frequency 10kHz spinal cord stimulation (SCS) for treating refractory PDN. The study found that patients who received a 10kHz SCS implant alongside conventional medical management experienced lasting pain relief, improved quality of life, and sleep at 24 months post-implantation. (Source: NeuroNews)

Repairing Broken Brain Circuits Offers New Potential for Parkinson's Disease Treatment

August 30, 2023 - Researchers are exploring the potential of repairing dysfunctional brain circuits to treat Parkinson's disease, with a focus on the interaction between the thalamus and the cortex. They found a significant reduction in connectivity in a specific subtype of cortical neurons in a Parkinson's state. Designer receptors activated by designer drugs (DREADDs) were used to manipulate nerve cell activity in animal models and partially restored connectivity between the thalamus and the cortex. (Source: Advanced Science News)

Personalized Transcranial Neuromodulation Holds Promise for Chronic Pain Management

August 30, 2023 - Researchers have explored ways to personalize repetitive transcranial magnetic stimulation (rTMS) for individuals with treatment-resistant chronic pain. A retrospective study reviewed scientific publications and found various methods for customizing cortical neuromodulation, including prediction-based rTMS, altering stimulation patterns, targeting non-motor areas, adjusting based on cortical networks/rhythms, deep sensory profiling, and tailoring motor rTMS specifics. (Source: Physicians Weekly)

Ischiorectal Approach Simplifies Cryoablation for Two Pudendal Neuralgia Cases

August 30, 2023 - In a dual case report, the authors describe a novel ischiorectal approach to cryoablation of the pudendal nerve using a handheld device. This approach offers a simplified and safe method for targeting the pudendal nerve, providing sustained pain relief for both patients with pudendal neuralgia, albeit one patient achieved major pain reduction for significantly longer and the other experienced delayed onset. (Source: Cureus)

Advancements in Transcranial Magnetic Stimulation to Personalize Chronic Pain Treatment

August 30, 2023 - In a study published in the August 2023 issue of Pain, researchers explore the potential of personalized repetitive transcranial magnetic stimulation (rTMS) for treating chronic pain. Through a systematic review of scientific literature, they identify various approaches to customize cortical neuromodulation, including prediction-based rTMS, altering stimulation patterns, targeting non-motor areas, and adjusting based on cortical networks/rhythms. (Source: Physicians Weekly)

Article Addresses Breakthrough Brain-Computer Interfaces That Restore Speech for Paralyzed Individuals

August 29, 2023 - Two recent studies featured in Nature demonstrate how advanced brain-computer interfaces (BCIs) empowered by artificial intelligence can decode brain signals and enable paralyzed individuals to regain their ability to speak. These BCIs directly convert brain activity related to attempted speech into audible speech, allowing users to communicate through a digital avatar. (Source: Everyday Health)

Article Addresses Noninvasive Vagus Nerve Stimulation to Alleviate Pain in Systemic Sclerosis

August 29, 2023 - In a study published in RMD Open, noninvasive therapy called transcutaneous auricular vagus nerve stimulation (tVNS) showed potential to safely reduce pain in individuals with systemic sclerosis (SSc). The study observed reduced pain levels and lower IL-6 (an inflammatory molecule) levels in SSc patients who used tVNS. (Source: Scleroderma News)

News Story Features Neuromodulation's Role in the Recovery of a Sacramento Woman Paralyzed in a Horseback Riding Accident

August 28, 2023 - A diaphragm pacing system played a crucial role in the recovery of a Sacramento woman who had been paralyzed in a horseback riding accident. (Source: ABC)

Article Addresses Transcranial Magnetic Stimulation for Various Mental Health Conditions

August 29, 2023 - Transcranial Magnetic Stimulation (TMS) has gained attention as a promising treatment for depression, but its potential extends to other mental health conditions. TMS involves the application of magnetic pulses to the brain's nerve cells, with proven effectiveness in treating depression. Research is exploring its application in conditions like Obsessive-Compulsive Disorder (OCD), addiction disorders, chronic pain, autism and Attention Deficit Hyperactivity Disorder (ADHD). (Source: Medical Xpress)

Article Addresses Deep Brain Stimulation Combined with Therapy for Stroke Recovery

August 29, 2023 - Research from the Cleveland Clinic reveals that deep brain stimulation (DBS) combined with physical therapy can significantly improve the quality of life and independent functioning of stroke patients, even years after their initial stroke. This study marks the first evidence of DBS effectively enhancing brain function post-stroke. (Source: Cleveland.com)

Company Initiates Trial to Address Cognitive Dysfunction in Long Covid Patients

August 29, 2023 - Soterix Medical has launched the Phase II RECOVER-NEURO clinical study, collaborating with NYU Langone Health's remotely supervised (RS) tDCS program. This trial, part of the Researching COVID to Enhance Recovery (RECOVER) Initiative led by the National Institutes of Health (NIH), aims to address cognitive issues associated with long Covid, such as brain fog, memory problems, and attention difficulties. The study will involve interventions, including Posit Science's cognitive training program, goal management training from Mount Sinai Health System, and Soterix Medical's home-based tDCS system. The trial will assess up to 315 participants and seeks to develop a long Covid treatment based on digital therapy and Soterix Medical's REMOTE-tDCS platform. (Source: Medical Device Network)

Article Addresses Initiative to Create Injectable Magnets That Restore Damaged Neurons' Functionality

August 29, 2023 - The BRAINSTORM project, a pan-European effort to develop an innovative treatment for neurological disorders, involves creating injectable magnets that could restore damaged neurons in patients' brains, potentially addressing conditions like depression, epilepsy, and Alzheimer's. (Source: newsd)

Meta-Analysis Reveals Mood and Quality of Life Benefits in Parkinson's Patients with Deep Brain Stimulation

August 26, 2023 - A comprehensive meta-analysis compared the effects of deep brain stimulation (DBS) in two target regions, subthalamic nucleus (STN) and globus pallidus internus (GPi), on mood and quality of life in Parkinson's disease (PD) patients. The analysis of 14 studies involving 1,088 patients showed that GPi stimulation led to greater improvements in mood and quality of life, as measured by various scales, compared to STN stimulation. However, STN stimulation exhibited advantages in reducing motor symptoms and medication usage, highlighting the complex trade-offs between these two DBS targets for PD treatment. (Source: Cureus)

Biomarker-Guided Neuromodulation Offers Potential for Memory Restoration in Traumatic Brain Injury Patients

August 24, 2023 - A collaborative study featured in Brain Stimulation reveals a promising breakthrough in the field of neuromodulation. Researchers, led by Michael Jacob Kahana at the University of Pennsylvania, applied targeted electrical stimulation to epilepsy patients with traumatic brain injuries, resulting in a 19% improvement in word recall memory. This innovative approach is guided by biomarkers and individual brain wiring. (Source: NeuroNews)

Company Implants Innovative Neuromodulation Device for Migraine and Cluster Headache Relief

August 24, 2023 - Salvia BioElectronics has successfully implanted its paper-thin neuromodulation device to treat severe migraine and cluster headaches, marking a significant development in headache treatment. The device, granted FDA breakthrough device designation in 2020, uses thin bioelectronic foils to deliver electrical pulses, offering relief by restoring brain balance. (Source: Medical Device Network)

Swine Model Study Explores Immediate Electromagnetic Field Stimulation's Impact on Cortical Injury

August 19, 2023 - Researchers have investigated the effects of immediate electromagnetic field (EMF) stimulation on cortical injury using a swine model. The study utilized proprietary non-contact induction sensors and an electromagnetic shielded helmet to measure EMF patterns in Yucatan mini-pigs with traumatic brain injury (TBI). The results showed that early EMF stimulation led to recovery in neuronal circuit-driven electromagnetic field patterns and increased viability of neurons. (Source: Cureus)

Enhancing Transcranial Ultrasound Procedures: Non-Invasive Blood-Brain Barrier Opening in Mice Using Oil for Hair-Coupling

August 19, 2023 - Researchers have developed a method to address the challenge of acoustic coupling through hairs in transcranial-focused ultrasound (tFUS) procedures by utilizing oil as a coupling medium. In a study involving mice, the technique was compared to traditional methods of coupling through hair shaving and ultrasound gel application. The results demonstrated that the "oil + hairs" approach effectively improved acoustic coupling without trapping air bubbles and achieved comparable outcomes in blood-brain barrier opening to the "ultrasound gel + no hair" group, highlighting the potential for more patient-friendly tFUS procedures without the need for hair shaving. (Source: Nature)

Deep Brain Stimulation Shows Promise to Treat Motor Issues Due to Stroke

August 18, 2023 - A phase 1 clinical trial testing deep brain stimulation in human stroke survivors shows promise in enhancing upper limb mobility. The trial combined deep brain stimulation with physiotherapy and found that the intervention was safe and led to improved movement in the upper limbs of individuals with moderate-to-severe upper-extremity impairment. (Source: MedicalNewsToday)

Article Addresses Promise of Vagal Nerve Stimulation for Stroke Patients

August 17, 2023 - A study with stroke patients found significant motor improvement using transcutaneous auricular vagus nerve stimulation. It offers a less invasive alternative to implanted devices and may improve the quality of life for stroke survivors. (Source: Forbes)

Phasic Auricular Vagus Nerve Stimulation Shows Modulatory Effects on Behavioral and Neurophysiological Responses

August 17, 2023 - In a study published in the Journal of Neuroscience, researchers applied phasic transcutaneous auricular vagus nerve stimulation (taVNS) during cognitive tasks, demonstrating its ability to modulate behavioral, pupillary, and electrophysiological responses linked to the noradrenergic system. The study also introduced the pupillary light reflex as a potential biomarker for taVNS efficacy. (Source: Journal of Neuroscience)

Company's Neuromodulation System for Incontinence Receives FDA De Novo Clearance

August 17, 2023 - BlueWind Medical has gained de novo clearance from the FDA for its neuromodulation system, Revi, designed to treat urge urinary incontinence (UUI). The system combines an ankle-worn wireless device with a small implanted device near the ankle, stimulating the tibial nerve to alleviate UUI symptoms. The clearance was based on positive results from the Oasis trial, with over three-quarters of participants experiencing reduced urge incontinence episodes. The system demonstrated high compliance rates and mild to moderate adverse effects. (Source: Fierce BioTech)

Non-Invasive Brain Stimulation Shows Promise in Improving Walking Ability for People with Parkinson’s

August 16, 2023 - Researchers in Japan have demonstrated the potential of transcranial electrical stimulation (TES) to alleviate the distinct walking difficulties associated with Parkinson's disease, known as "Parkinsonian gait." By delivering a low electric current to stimulate the cerebellum on the side of the body with severe symptoms, the treatment group in a study showed significant improvements in walking speed, step length, and gait symmetry, along with reduced freezing of gait. (Source: FreeThink)

Study Reveals Home-Use Binaural Beats Brain Stimulation May Impair Cognitive Function Instead of Enhancing It

July 8, 2023 - A study conducted on 1000 individuals found that using binaural beats brain stimulation during cognitive tasks at home significantly deteriorated test scores, contradicting the belief that it enhances cognitive function, while silence or other sounds had no effect. The findings suggest that home-use binaural beats brain stimulation may have reverse effects, weakening rather than supporting cognitive activities. (Source: Nature)

Company Launches Advanced FDA-Cleared Transcranial Magnetic Stimulation System in UK

July 7, 2023 - Magstim's FDA-cleared Horizon 3.0 transcranial magnetic stimulation (TMS) system is now available for sale in the UK, empowering physicians to advance the treatment of depression, OCD, and anxious depression with non-invasive brain stimulation, as shown by positive patient responses and over 16,000 published studies using Magstim technology. (Source: Yahoo! Finance)

Study Suggests Poor Knowledge and Unfavorable Attitudes Towards Deep Brain Stimulation Among Saudi Arabian Medical Students

July 7, 2023 - A study conducted in Saudi Arabia has found that almost half of the medical students surveyed displayed poor knowledge and unfavorable attitudes towards deep brain stimulation (DBS). The study highlights the need to improve DBS education in medical curricula to ensure future patients have access to this effective therapeutic option. (Source: Cureus)

New Study Links Long COVID Symptoms to Vagus Nerve Damage

July 7, 2023 - A study conducted in Spain on individuals experiencing Long COVID symptoms revealed that two-thirds of them reported symptoms associated with vagus nerve dysfunction, such as persistent cough, changes in speech, and difficulty swallowing. The study also found structural changes and thickening in the vagus nerve, as well as observable flattening of the diaphragm, suggesting that damage to the vagus nerve may be responsible for respiratory and other symptoms in Long COVID patients. (Source: Forbes)

Study Finds Neural Mechanisms of Emotional Health Improved in Traumatic Brain Injury Patients with rTMS Treatment

July 6, 2023 - A study investigated the neural mechanisms underlying the improvement of emotional health in patients with traumatic brain injury (TBI) undergoing repetitive transcranial magnetic stimulation (rTMS) treatment. Using resting-state functional magnetic resonance imaging (fMRI) and spectral dynamic causal modeling (spDCM), the study identified changes in brain effective connectivity, particularly in the dorsal anterior cingulate cortex (dACC), left anterior insula, and medial prefrontal cortex, suggesting potential neural mechanisms for the improvement of emotional health in TBI patients. (Source: Nature)

Study Finds Cochlear Implant Surgery Does Not Affect Mastoid Volume Growth in Children

July 6, 2023 - A recent study investigated the development of mastoid volume in children who underwent cochlear implantation surgery and found that the mastoid volume increased over time, indicating normal growth. The study also observed linear measurements between anatomical points in the mastoid bone, showing a positive correlation with mastoid volume. The findings suggest that cochlear implant surgery does not impact the natural growth of the mastoid air cell system in children. (Source: Nature)

Brain-Spine Interface Shows Promise in Restoring Motor Function in Spinal Cord Injury Patients

July 6, 2023 - A Swiss research team has successfully restored standing, walking, and stair-climbing abilities in a 38-year-old man with a cervical spinal cord injury using an implanted brain-spine interface (BSI). The BSI, consisting of implanted electrodes and an artificial intelligence algorithm, captured neural signals from the brain and wirelessly transmitted them to an epidural stimulator targeting the spinal cord, allowing the patient to regain motor control. (Source: Neurology Today)

Artificial Intelligence Shows Promise in Enhancing Deep Brain Stimulation for Neurological Disorders

July 5, 2023 - Researchers are exploring how artificial intelligence (AI) can improve outcomes in deep brain stimulation (DBS). AI is being investigated for facilitating target localization during electrode placement and optimizing stimulation parameters, with the potential to enhance precision and efficiency in DBS procedures. (Source: Forbes)

Study Reveals Unique Brain Circuitry in Depression after Traumatic Brain Injury and Highlights the Value of Transcranial Magnetic Stimulation

July 5, 2023 - Transcranial magnetic stimulation (TMS) is highlighted as a potentially effective treatment for depression related to traumatic brain injury (TBI), offering the ability to stimulate or inhibit specific brain circuits that may be overactive or underactive in TBI-related depression, providing a more targeted therapeutic approach. (Source: NBC News)

Case Report on Anesthetic Management During Hemiarthroplasty Surgery for Parkinson's Disease Patient with Deep Brain Stimulator Device

July 5, 2023 - A case report discusses the anesthetic management of a 75-year-old patient with Parkinson's disease (PD) and a deep brain stimulator (DBS) device undergoing urgent hemiarthroplasty surgery, and highlights the considerations and challenges associated with DBS devices in the perioperative period, including electromagnetic interference, medication management, device activation, and postoperative care. (Source: Cureus)

New Partnership Explores the Intersection of AI and Neuromodulation for Sleep Disorders

July 4, 2023 -Two professors are collaborating to develop electronic devices that can investigate sleep modulation and potentially offer interventions for sleep disorders. By integrating machine learning algorithms into wireless systems-on-chips, the researchers aim to gain a deeper understanding of sleep patterns and disorders and incorporate neural interfacing capabilities to enable precise interventions. The project is supported by a $2.2 million grant from the National Institutes of Health. (Source: University of Toronto Engineering News)

Study Investigates COVID-19's Impact on the Brain and Therapeutic Avenues for Long COVID

July 4, 2023 - This article explores the detrimental effects of COVID-19 on the brain, highlighting the presence of neurological symptoms in patients with long COVID, including the potential role of Epstein-Barr virus reactivation and changes in the gut microbiome, as well as therapeutic options such as dietary interventions, probiotics, fecal microbiota transplantation, vagus nerve stimulation, and the use of the sigma-1 receptor agonist fluvoxamine. (Source: Nature)

Article Explores the Versatility of Vagus Nerve Stimulation for Mental and Physical Health Improvement

July 4, 2023 - This article discusses the ability of vagus nerve stimulation (VNS) to influence brain activity and activate anti-inflammatory pathways, and how VNS has shown promise in epilepsy, depression, and now holds potential for conditions such as rheumatoid arthritis and Crohn's disease. (Source: Scientific American)

Transcranial Direct Current Stimulation Shows Limited Efficacy as an Add-On Treatment to SSRIs for Major Depressive Disorder

July 3, 2023 - A triple-blind, randomized, and sham-controlled trial conducted in Germany, known as the DepressionDC trial, investigated the efficacy of transcranial direct current stimulation (tDCS) as an additional treatment to selective serotonin reuptake inhibitors (SSRIs) in adults with major depressive disorder (MDD). The study found that tDCS was not superior to sham stimulation in improving depressive symptoms over a 6-week period, thus not supporting its effectiveness as an adjunct therapy for MDD. (Source: The Lancet)

Lesion Network Mapping Reveals New Brain Circuit Linked to Epilepsy and Has Potential Brain Stimulation Implications

July 3, 2023 - A study conducted by researchers at the Brigham and Women's Hospital has identified a common brain circuit that may link different lesion locations causing epilepsy. By utilizing lesion network mapping, the researchers found that the disrupted brain connections, rather than the specific lesion locations, were key factors associated with epilepsy. The findings provide potential targets for brain stimulation and may have clinical implications for predicting the risk of epilepsy following brain damage. (Source: News Medical)

Scientists Discover Brain Region that Triggers Out-of-Body Experiences

July 3, 2023 - Scientists have identified a specific area of the brain, known as the anterior precuneus, that when stimulated, can induce out-of-body experiences. The research conducted by Dr. Josef Parvizi and his team at Stanford found that electrically stimulating the anterior precuneus led to changes in participants' sense of their physical self, suggesting the critical role of this brain region in our perception of personal identity and physical presence. (Source: NPR)

Article Addresses the Role of Sleep Deprivation in Depression and Potential Neuromodulation Implications

July 3, 2023 - This article addresses a study on the relationship between sleep deprivation and depression relief. Exploring the neural mechanisms involved, the research may present useful insight into candidate targets for transcranial magnetic stimulation (TMS). (Source: Scientific American)

Study Suggests Improved Outcomes for Teens with Cochlear Implants

June 30, 2023 - According to a study published in JAMA Otolaryngology-Head & Neck Surgery, adolescents with cochlear implants (CIs) experience improved language skills, academic performance, and quality of life compared to those without CIs, highlighting the importance of early identification and intervention for children with hearing loss. (Source: HealthDay News)

Ethical Considerations in Rapid and Novel Treatments Such As Neuromodulation in Psychiatry

June 30, 2023 - This article delves into the ethical considerations surrounding rapid and novel treatments in psychiatry, including psychedelics and neuromodulation, focusing on areas such as informed consent, the role of expectancy in clinical response, and distributive justice. The authors emphasize the need for careful navigation and ethical guidelines to address the complexities of these treatments. (Source: Nature)

Electrical Stimulation of Vagus Nerve Shows Promise in Reversing Chronic Inflammation

June 29, 2023 - Electrical stimulation of the vagus nerve, which controls many autonomic functions in the body, has been found to regulate inflammation and may offer a new treatment approach for chronic inflammatory conditions such as rheumatoid arthritis and Crohn's disease. Clinical trials have shown that vagal nerve stimulation reduces symptoms and inflammation, highlighting the potential of this novel therapeutic approach. (Source: Forbes)

Researchers Develop Optogenetics Tool to Study Gut-Brain Connection

June 29, 2023 -  Scientists have developed a specialized optogenetics tool using long, flexible fibers equipped with electrodes and light emitting devices to stimulate nerve cells in the gut. By using this technology, they were able to mimic behavioral changes associated with brain stimulation, shedding light on the gut-brain connection and its potential involvement in conditions such as Parkinson's disease. (Source: Parkinson’s News Today)

Brain-Computer Interface with Sense of Touch Enhances Mobility for Paralyzed Individuals

June 28, 2023 - A study published in Science demonstrates the potential of a bidirectional brain-computer interface (BCI) that combines vision and touch to improve the control of robotic limbs by paralyzed individuals. By recording neural activity and evoking tactile sensations through cortical stimulation, the BCI enabled a quadriplegic patient to enhance their performance and achieve task completion times closer to those of able-bodied individuals. (Source: Psychology Today)

Chemical Imbalance in Forebrain Linked to Obsessive-Compulsive Disorder

June 27, 2023 - Researchers at the University of Cambridge have discovered an imbalance between the neurotransmitters glutamate and GABA in the frontal lobes of individuals with obsessive-compulsive disorder (OCD). The findings suggest a dysregulation of the brain system for controlling habits, providing new insights into the underlying mechanisms of OCD and treatment avenues including deep brain stimulation and transcranial magnetic stimulation. (Source: Science Daily)

Brain Activity Patterns in Orbitofrontal Cortex Can Predict Chronic Pain State

June 28, 2023 - A recent study has identified a biomarker for chronic pain severity by analyzing brain activity in patients' orbitofrontal cortex (OFC), marking the first objective biomarker for chronic pain. The findings suggest that neuromodulation techniques, such as personalized brain stimulation, could be potential therapies for individuals with refractory chronic pain. (Source: Pain Medicine News)

Article Review Addresses The Potential of Closed-Loop Neurostimulation for Psychiatric Disorders

June 27, 2023 - Psychiatric diseases pose a significant challenge due to their varied presentation and symptoms, making one-size-fits-all treatments ineffective. Closed-loop neurostimulation, which utilizes biomarkers and device-driven stimulation during symptomatic periods, shows promise in providing personalized therapy for psychiatric disorders. This article reviews the use of open- and closed-loop neurostimulation, particularly deep brain stimulation, as a potential treatment approach and discusses important considerations for implementing closed-loop neurostimulation in the field of neuropsychiatry.  (Source: Nature)

Revolutionary Nanoelectrode Enables High-Resolution Brain Stimulation with Unprecedented Precision

June 26, 2023 - Researchers at Rice University have developed a flexible nanoelectrode that allows for highly precise and discreet brain stimulation. This breakthrough technology offers the potential for finer control over small groups of neurons and long-term implantation without causing tissue damage or scarring. By delivering low-current electrical pulses, the nanoelectrode achieve notable efficacy and paves the way for advanced applications such as brain-machine interfaces and enhanced sensory encoding. (Source: Medgadget)

Study Addresses Application of Vagus Nerve Stimulation for Inflammatory Conditions 

June 23, 2023 - This study suggests that α7nAChR signaling enhances cell-cell interactions in macrophages, resulting in anti-inflammatory effects and organ protection. This research highlights the potential of targeting α7nAChR signaling through vagus nerve stimulation for developing anti-inflammatory strategies for conditions such as acute kidney injury. (Source: Nature)

Article Discusses How Parkinson's Diagnosis Ends Med Student's Surgeon Dream, but Deep Brain Stimulation Offers Hope

June 23, 2023 - Joe Salazar, a medical student diagnosed with Parkinson's disease at the age of 25, shares his journey of shattered dreams and renewed hope after undergoing a transformative Deep Brain Stimulation (DBS) procedure that significantly improved his quality of life, highlighting the potential benefits of DBS for Parkinson's patients. (Source: People)

Article Explores Potential of Brain-Machine Interfaces in Mental Health Treatment

June 23, 2023 - Brain-machine interfaces (BMIs) offer a new paradigm for treating mental health disorders, with potential applications including deep brain stimulation (DBS) and non-invasive techniques like transcranial magnetic stimulation (TMS) and electroencephalography (EEG). Recent studies have shown promising results in reducing symptoms of depression and post-traumatic stress disorder (PTSD) using closed-loop BMI systems, highlighting the potential for more targeted and effective interventions in the future. (Source: CityLife)


Article Addresses Deep Brain Stimulation for Parkinson's Patients for Relief from Motor Symptoms and Restoring Quality of Life

June 22, 2023 - Article on Carl McLain, a Parkinson's disease patient, who underwent deep brain stimulation (DBS) surgery to alleviate his symptoms. While the treatment does not cure Parkinson's, it helps control symptom fluctuations and provides patients with improved quality of life, allowing them to regain functionality and pursue activities they enjoy. (Source: UT Health)

NFL and NFLPA Fund Research on Non-Invasive Vagal Nerve Stimulation (nVNS) for Athlete Pain Management

June 22, 2023 - The National Football League (NFL) and the NFL Players Association (NFLPA) are providing research grants to study the effects of non-invasive vagal nerve stimulation (nVNS) on pain management and performance in athletes. These studies aim to investigate the potential benefits of nVNS as an alternative pain management method for NFL players and potentially for athletes in general. (Source: NFL)

Pilot Study Shows Highly Targeted Electrical Brain Stimulation May Improve Blood Flow in Stroke Patients

June 22, 2023 - In a pilot study conducted by researchers at the University of California, Los Angeles, the effectiveness of high-definition cathodal transcranial direct current stimulation (HD C-tDCS) in improving blood flow in acute ischemic stroke patients was evaluated. By applying a weak inhibitory electrical current to the specific area of the brain with low blood flow, this noninvasive stimulation technique demonstrated potential benefits in protecting the penumbra from irreversible damage and enhancing blood flow. (Source: Medical Daily)

Study Finds Auricular Transcutaneous Vagus Nerve Stimulation Enhances Working Memory Gate Closing Mechanism

June 21, 2023 - A recent study published in the Journal of Neuroscience explores the effects of auricular transcutaneous vagus nerve stimulation (atVNS) on working memory (WM) gating dynamics. The study reveals that atVNS specifically modulates the closing of the WM gate, facilitating the maintenance of information in working memory. This modulation is achieved through the modulation of EEG alpha band activity in regions associated with stimulus information, motor response information, and stimulus-response mapping rules. The findings suggest that atVNS enhances the ability to shield information from distraction. (Source: The Journal of Neuroscience)

Study Suggests Repetitive Transcranial Magnetic Stimulation May Benefit Late-Life Depression Patients

June 19, 2023 - A study on late-life depression patients suggests that repetitive transcranial magnetic stimulation (rTMS) may be effective, with higher remission rates observed in participants with fewer prior medication trials, indicating the potential benefits of early utilization of rTMS in depression treatment. (Source: Cambridge)

Robot-Assisted Deep Brain Stimulation Surgery Shows Promise for Treating Epilepsy

June 18, 2023 - A neurosurgeon in Canada has successfully performed robot-assisted deep brain stimulation surgery on epilepsy patients, with three surgeries completed since January. The procedure involves implanting electrodes in specific brain areas to restore function and prevent seizures, similar to a pacemaker for the heart. (Source: Interesting Engineering)

China Approves Company's Sacral Nerve Stimulation System for Bladder and Bowel Conditions

June 16, 2023 - General Stim Inc. has received approval in China for its implanted sacral nerve stimulation (SNS) system, which is used to treat bladder and bowel conditions. The system includes a sacral nerve stimulator, an extension lead, and an electrode. (Source: Bio World)

Obstructive Sleep Apnea Common After Vagus Nerve Stimulation Implantation

June 16, 2023 - A meta-analysis presented at a sleep medicine conference revealed that obstructive sleep apnea (OSA) is a common adverse event following vagus nerve stimulation (VNS) implantation in patients with intractable epilepsy. The study emphasized the importance of monitoring patients for OSA after VNS treatment. (Source: Pulmonology Advisor)

Study Suggests Psychedelic Drugs and Brain Stimulation Show Potential Synergistic Effect

June 16, 2023 - New research published in the journal Psychedelic Medicine suggests that psychedelic drugs, such as LSD, can alter the effects of brain stimulation, leading to potentially larger changes in brain activity. The study highlights the possibility of using a combination of psychedelic drugs and brain stimulation, such as TMS, as an innovative approach for treating various conditions, although further research is needed to explore the long-term effects and behavioral changes associated with this approach. (Source: PsyPost)

Article Explores Potential of Neuromodulation in Treating Anorexia Nervosa and Bulimia

June 16, 2023 - Repetitive transcranial magnetic stimulation (rTMS) and deep brain stimulation (DBS) are being investigated as potential treatments for anorexia nervosa and bulimia nervosa, with promising but limited findings. (Source: Psychiatric Times)

Implanted Brain-Spine Interface Restores Standing and Walking Ability in Man with Spinal Cord Injury

June 15, 2023 - A Swiss team has successfully enabled a 38-year-old man with a cervical spinal cord injury to regain the ability to stand and walk using an implanted brain-spine interface (BSI). The BSI captured neural signals from the sensorimotor cortex and wirelessly transmitted them to an epidural stimulator, allowing the man to control his leg muscles and perform movements with the aid of an artificial intelligence algorithm. Further research with additional participants is planned. (Source: Neurology Today)

Study Explores Core Elements of Accelerated TMS for Rapid Treatment of Depression

June 15, 2023 - A recent review article in Neuropsychopharmacology explores the core elements of accelerated transcranial magnetic stimulation (TMS) for the treatment of major depressive disorder (MDD). The authors highlight various categories, including treatment parameters, cumulative exposure, individualized parameters, and brain state. (Source: Psychiatric Times)

News Broadcast Addresses Brain Implant Industry and Its Medical Possibilities

June 14,  2023 - Academics from the Center for Neurotechnology at the University of Washington and the department of Medical Ethics and Health Policy at the University of Pennsylvania speak alongside the Chief Commercial Officer of Synchron about the brain implant industry and its medical possibilities. (Source: 1A WAMU NPR)

Study Suggests Spinal Cord Burst Stimulation Not Superior to Placebo for Chronic Radicular Pain After Lumbar Spine Surgery

June 13, 2023 - A recent six-month post hoc follow-up study examined the efficacy of spinal cord burst stimulation in patients with chronic radicular pain after lumbar spine surgery. The study concluded that burst stimulation was not superior to placebo in improving pain-related disability, highlighting the limitations of blinding treatment allocation and the inability to fine-tune stimulation parameters in the original trial. (Source: JAMA Network)

FDA Clears Company's OCD Motor Threshold Cap for Transcranial Magnetic Stimulation System

June 13, 2023 - The FDA has granted 510(k) clearance to Neuronetics for its obsessive-compulsive disorder (OCD) motor threshold cap technology, an addition to the NeuroStar transcranial magnetic stimulation system. The cap streamlines the treatment process by providing a consistent starting location and mapping process, reducing the time and steps involved in coil placement, and aims to enhance treatment efficiency and personalized care for individuals with OCD. (Source: Healio)

Deep Brain Stimulation Literature Review Reveals Improved Clinical Outcomes and Future Prospects for Movement Disorders

June 13, 2023 - A literature review reveals significant advancements in deep brain stimulation (DBS) for movement disorders, leading to improved clinical outcomes and offering promising avenues for future research and development. (Source: Cureus)

Breakthrough Research on Dissolvable Coatings Paves the Way for Implantable Treatments for Epilepsy

June 12, 2023 - University of Glasgow researchers have made significant progress in developing dissolvable coatings for flexible neural probes used in the treatment of temporal lobe epilepsy. The novel materials offer improved compatibility with brain tissue, reducing the risk of scarring and enabling more effective placement of the probes, bringing the possibility of a cure for epilepsy closer to reality. (Source: Phys.org)

TMS Investigated as Potential Treatment for Eating Disorders in Novel Research Program

June 12, 2023 - Monash University's Li Transformative Hub for Research in Eating Disorders (THRED) aims to explore biological causes and treatments for eating disorders, including the investigation of transcranial magnetic stimulation (TMS) to potentially "re-program" the brains of individuals with eating disorders, as part of a multi-faceted approach to improving treatment outcomes. (Source: Monash University)

Advances in Brain-Spine Interfaces Hold Promise for Movement Restoration after Spinal Cord Injuries

June 12, 2023 - Brain-spine interface technology advances to restore movement in individuals with lower body motor impairments caused by spinal cord injuries. A digital bridge translates neural signals, enabling brain-driven muscle movement and offers promising progress in motor function restoration. (Source: Forbes)

Medtronic Warns of Potential Damage to Vanta Neurostimulators During Cardioversion Therapy

June 12, 2023 - Medtronic has issued a field safety notice warning neurosurgeons that one of the models in its Vanta range of implantable neurostimulators may become unresponsive and non-functional if patients undergo cardioversion therapy for heart rhythm restoration. The notice advises temporary reprogramming of the device during the procedure to mitigate the risk and highlights updated manuals and labeling to enhance patient awareness and reduce potential damage. (Source: Fierce Biotech)

MRI and TMS-EEG Study Reveals Adolescent Binge Drinking Leads to Long-Term Brain Changes and Altered Neurotransmission in Young Adults

June 12, 2023 - Young adults who engaged in heavy alcohol consumption during their teenage years exhibited reduced cortical gray matter thickness and modified neurotransmission, specifically increased N45 potential, highlighting the detrimental impact of adolescent heavy drinking on adult brain structure and function. MRI and simultaneous TMS-EEG were leveraged to measure gray matter changes. (Source: Neuroscience News)

Article Addresses Addition of Spinal Cord Stimulation to Nebraska Hospital

June 11, 2023 - A physician has introduced spinal cord stimulation to the in-house practices of Methodist Physicians Clinic in Nebraska, and advocates for the importance of a collaborative approach to pain management, including physical medicine and rehabilitation, primary care physicians, physical therapists, neurosurgeons, and orthopedic surgeons to provide quality patient care. (Source: Omaha World-Herald)

New Mouse Model Reveals Role of Zinc in Neuromodulation

June 9, 2023 - The development of a new mouse model could lead to new insights into the role of zinc in neuromodulation and to the development of new treatments for neurological disorders. (Source: Science)

SO-tDCS Improves Memory Consolidation During Restricted Sleep

June 8, 2023 - A study finds slow oscillatory transcranial direct current stimulation (SO-tDCS) improved memory consolidation in healthy patients during restricted nighttime sleep. (Source: Neurology Live)

Neuromodulation Offers New Treatment Option for Obstructive Sleep Apnea

June 7, 2023 - Upper airway stimulation therapy, which is delivered by stimulating the hypoglossal nerve, uses electrical stimulation to treat obstructive sleep apnea and has been proposed as an effective alternative for those who are unable to tolerate a CPAP. (Source: Mayo Clinic Health System)

Spinal Cord Stimulation Shows Promise in Helping Paraplegic Patients Walk Again

June 7, 2023 - A clinical trial of 20 patients at Hennepin Healthcare in Minneapolis has found that spinal cord stimulation can help paraplegic patients regain some movement in their legs. After receiving the implant, patients reported improvements in movement, mobility, blood circulation, and bowel and bladder control. (Source: Kare11 News)

Transcranial Magnetic Stimulation Shows Promise in Helping Smokers Quit

June 7, 2023 - A recent study found that repetitive TMS was effective in helping smokers quit, with a quit rate of 28% after 12 weeks. (Source: Nature)

Deep Brain Stimulation Study Finds Brain Activity Patterns Can Predict Chronic Pain

June 6, 2023 - Researchers have identified brain activity patterns that are associated with chronic pain in a study with four participants. They also studied deep brain stimulation (DBS) as a potential treatment for chronic pain, but more research is needed to confirm its effectiveness. (Source: National Institutes of Health)

University Researchers Use Vagus Nerve Stimulation to Treat Hypermobile Ehlers-Danlos Syndrome

June 6, 2023 - A team of researchers at MUSC has received a Blue Sky Award to investigate the use of vagus nerve stimulation (VNS) to treat hypermobile Ehlers-Danlos syndrome (hEDS). This award is granted to potentially high-value research projects that are unlikely to receive traditional funding. (Source: Medical University of South Carolina)

Study Finds Obstructive Sleep Apnea Common Side Effect of Vagus Nerve Stimulation

June 5, 2023 - A study found that 27.3% of patients who received vagus nerve stimulation (VNS) for epilepsy or depression developed obstructive sleep apnea (OSA). The study's authors recommend that neurosurgeons screen patients for OSA before and after VNS implantation. (Source: Neurology Live)

Study Finds Targeted Deep-Brain Stimulation During Sleep Can Enhance Memory Consolidation

June 2, 2023 - A study by researchers at UCLA and Tel Aviv University finds targeted deep-brain stimulation (DBS), when performed during a specific sleep phase, can enhance memory consolidation. The study, which was published in the journal Nature Neuroscience, could provide new insights into how DBS could potentially treat memory disorders such as Alzheimer's disease. (Source: Neuroscience News)

Study Finds Spinal Cord Stimulation Can Help Paralyzed Patients Regain Function

June 2, 2023 - A clinical trial at HCMC in Minneapolis is showing that spinal cord stimulation can help paralyzed patients regain function, even if they have been injured for many years. The study is still ongoing, but the early results are varied yet promising. (Source: StarTribune)

Study suggests Vagus Nerve Stimulation During Sleep May Improve Memory

June 2, 2023 -  A study published in Nature Neuroscience found that deep brain stimulation during sleep during non-REM sleep improved memory in people with severe epilepsy. The researchers believe that this approach could be used to improve memory in people with other conditions, such as Alzheimer's disease. (Source: NPR)

Study Shows Higher Survival Rates for Pediatric Patients with Drug-Resistant Epilepsy Treated with Surgery or Vagus Nerve Stimulation

June 2, 2023 - A recent observational cohort study comparing treatment options for pediatric patients with drug-resistant epilepsy found that those who underwent cranial epilepsy surgery or received vagus nerve stimulation (VNS) had higher survival rates compared to those who received only medical treatment. (Source: The Lancet)

Adolescent Neurostimulation of Dopamine Circuit Shows Potential for Treating Neuropsychiatric Disorders

June 2, 2023 - Researchers at the University of Rochester used neurostimulation during critical developmental windows to target underperforming dopamine neurons in mice, leading to long-lasting changes that corrected structural brain deficiencies associated with neuropsychiatric disorders like schizophrenia and autism. This suggests the potential for interventions during specific developmental periods to alter the course of these disorders. (Source: Neuroscience News)

Study Reveals Brain's Memory Consolidation Process During Sleep

June 1, 2023 - New research demonstrates how the brain consolidates memories during sleep by stimulating specific brain regions. The study's brain stimulation technique shows potential for future advancements in memory research and therapeutic interventions. (Source: USA Today)

Computational Models Predict Vagus Nerve Stimulation Thresholds in Preclinical Animals and Humans

May 31, 2023 - Validated computational models, utilizing ASCENT software, accurately simulate the effects of vagus nerve stimulation (VNS) in humans, pigs, and rats. The models incorporate various factors such as nerve histology, device design, tissue conductivities, and realistic fiber models, successfully predicting activation thresholds for different species and fiber types. The study highlights the potential of these models in understanding the therapeutic and side effects of VNS and individual-specific variations in neural responses. (Source: IOP Science)

Interview Features Physician's Insights Microburst Vagus Nerve Stimulation for Drug-Resistant Epilepsy

May 31, 2023 - In an interview, Dr. Cornelia Drees, a senior associate consultant in the Department of Neurology at Mayo Clinic, highlights the potential of microburst vagus nerve stimulation (VNS) as a targeted treatment for drug-resistant epilepsy. Microburst VNS differs from traditional VNS by delivering stimulation at higher frequencies in short bursts, showing promising results in reducing seizure frequency and improving quality of life in patients. (Source: NeurologyLive)

Engineers Develop Flexible Nanoelectrodes for Fine-Grained Brain Stimulation

May 30, 2023 - Rice University engineers have created ultraflexible nanoelectrodes that can be implanted in the brain for long-term, high-resolution stimulation therapy. The devices exhibit high biocompatibility and precise control over stimulus patterns, offering potential for sensory prostheses and improved treatment for conditions such as Parkinson's disease, epilepsy, and obsessive-compulsive disorder (OCD). (Source: Science News)

Nerve Stimulation Shows Promise in Tobacco De-addiction

May 30, 2023 - Dr. M.S. Reddy, a psychiatrist, has introduced a non-invasive neuromodulation treatment using deep transcranial magnetic stimulation (TMS) to help tobacco users quit their addiction. The treatment has shown success in 27 out of 60 patients, with others significantly reducing tobacco use. (Source: Deccan Chronicle)

Interview Addresses DARPA's Brain Hacking Experiment: Transforming a Science Writer into a Precision Shooter

May 29, 2023 - In a conversation with journalist Rose Eveleth, former editor of IEEE Spectrum, Sally Adee, discusses the potential implications of transcranial direct current stimulation (tDCS) technology. Adee touches upon concerns about the democratization of tDCS, the risks of self-experimentation, the limited understanding of its efficacy, the ethical considerations in sports and the workplace, and the need to approach emerging bioelectricity research, including tDCS, with clear eyes, avoiding the tendency to fit it into pre-existing narratives. (Source: Bulletin of the Atomic Scientists)

FDA Clears Company’s Micro-Implant Neurostimulation System for Chronic Peripheral Nerve Pain Treatment

May 29, 2023 - The FDA has granted clearance to Neuspera's micro-implant neurostimulation system, making it the first ultra-miniaturized peripheral nerve stimulation device approved for treating chronic peripheral nerve pain. The wireless platform, including a wearable transmitter and iPad-based clinician programmer, offers improved patient experience and procedural flexibility, allowing physicians to target deeper anatomical sites for pain relief. (Source: Pain Medicine News)

Wireless Brain-Computer Interface Enables Thought-Controlled Movement in Spinal Cord Injury Patients

May 27, 2023 - A study in Nature demonstrates the potential of a wireless brain-computer interface (BCI) paired with ARC Therapy to restore thought-controlled movement in individuals with spinal cord injury (SCI). The BCI establishes a continuous link between movement intentions and spinal cord stimulation, allowing for more natural mobility restoration. The ongoing clinical feasibility study shows promising safety and preliminary effectiveness in brain-controlled spinal cord stimulation after SCI. (Source: News Medical)

Analysis of Brain Stimulation Studies Explores Efficacy in Enhancing Memory and Focus

May 26, 2023 - A comprehensive analysis of over 100 studies on transcranial alternating current stimulation (tACS) and, suggests that these methods can lead to moderate improvements in attention, memory, problem-solving, and other cognitive processes. However, some researchers argue that the diverse nature of the studies makes it difficult to draw definitive conclusions. (Source: Nature)

Deep Brain Stimulation of Anterior Nucleus of the Thalamus Shows Efficacy in Drug-Resistant Epilepsy

May 26, 2023 - A study published in Neurology presents the results of the Medtronic Registry for Epilepsy (MORE), which assessed the safety and effectiveness of deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) in patients with drug-resistant epilepsy. The study showed a significant reduction in seizure frequency and a responder rate consistent with previous clinical trials. However, adverse events such as changes in seizure patterns, memory impairment, and depressive mood were reported, underscoring the need for careful monitoring during DBS therapy. (Source: Physicians Weekly)

Neuralink Receives FDA Approval for First In-Human Clinical Study of Brain Implant Technology

May 26 2023 - Neuralink, Elon Musk's neurotech startup, has gained FDA approval for its first in-human clinical study, allowing it to move forward with testing its brain implant called the Link, which aims to help patients with severe paralysis control external technologies using neural signals. (Source: CNBC)

Article Shares Patient Experience of Brain-Spine Interface That Enabled Natural Walking After Spinal Cord Injury

May 24, 2023 - As featured in Nature, researchers developed a brain-spine interface (BSI) that restored communication between the brain and the spinal cord in a person with chronic tetraplegia, allowing them to stand and walk naturally. The BSI, which consists of implanted recording and stimulation systems, facilitated control over leg movements and improved neurological recovery, offering a framework for restoring movement in individuals with paralysis. (Source: Science)

Head-Worn Device Utilizes Machine Learning and Brain Imaging to Differentiate Hand Gestures

May 23, 2023 - Researchers at the University of California San Diego have developed a head-worn wearable device that uses machine learning and magnetoencephalography (MEG) to differentiate hand gestures. The device achieved over 85% accuracy in distinguishing gestures in a trial. This technology has the potential to assist individuals with paralysis or amputated limbs in controlling devices using their minds. (Source: Health IT Analytics)

Breakthrough in Decoding Brain Signals Reveals Objective Biomarker for Chronic Pain

May 22, 2023 - For individuals with intractable chronic pain, researchers have successfully decoded brain activity underlying chronic pain for the first time. The findings may have an impact on deep brain stimulation clinical trials. The study identified brain regions associated with pain and developed an algorithm to predict pain levels based on electrical signals in the brain, which may provide opportunity for personalized therapies. (Source: Guardian)

Study Addresses Accelerated TMS for Faster Relief of Depression Symptoms

May 22, 2023 - Accelerated transcranial magnetic stimulation (TMS) protocols have shown potential for reducing treatment duration and improving response time in major depressive disorder (MDD). This study reviews nine elements around accelerated TMS including treatment parameters, cumulative exposure, individualized parameters, and brain state. (Source: Nature)

Vagal Nerve Stimulation Explored as Potential Treatment for New-Onset Refractory Status Epilepticus

May 21, 2023 - Researchers propose the consideration of vagal nerve stimulation (VNS) as a well-tolerated intervention for new-onset refractory status epilepticus (NORSE). Although limited evidence exists, VNS shows potential in reducing seizure burden and modulating ictogenesis, highlighting the need for further investigation through clinical trials. (Source: AJMC)

Deep Brain Stimulation Shows Cost-Effectiveness and Clinical Efficacy for Advanced Parkinson's Disease

May 19, 2023 - A prospective study of 73 adults conducted in Vietnam compared deep brain stimulation (DBS) surgery to medical therapy in patients with advanced Parkinson's disease (PD). The study found that DBS was more cost-effective and improved motor function, reducing "off" time and dyskinesia in patients. (Source: Healio)

Stanford Study Reveals How Transcranial Magnetic Stimulation Treats Depression

May 18, 2023 - A Stanford study has found that transcranial magnetic stimulation (TMS) treats depression by reversing the direction of abnormal brain signals. Backward streams of neural activity between specific areas of the brain were highlighted as a potential biomarker to diagnose depression. (Source: Neurology Live)

Article Shares First Person Experience in Study for Spinal Cord Injury Recovery

May 18, 2023 - An news story covers a news anchor who is part of a research study at the University of Louisville. The study uses epidural stimulation to help individuals with spinal cord injuries regain muscle control and independence, showing promising progress in the patient’s ability to stand and improve mobility. (Source: WISN)

Tactile Stimulation at 40 Hz Frequency Shows Promise in Alzheimer's Treatment

May 18, 2023 - Researchers have found that daily exposure to tactile stimulation at a frequency of 40 Hz can reduce Alzheimer's disease pathology and improve motor function. The study conducted on Alzheimer's model mice demonstrated a decrease in phosphorylated tau levels, protection against neuronal damage and synaptic loss. This discovery suggests the potential for non-invasive therapeutic strategies in treating neurodegenerative diseases like Alzheimer's. (Source: Neuroscience News)

FDA Approves Spinal Cord Stimulation Devices for Non-Surgical Back Pain

May 16, 2023 - Abbott received FDA approval for its entire portfolio of spinal cord stimulation (SCS) devices for patients with chronic back pain who have not had or are ineligible for surgery. This approval includes the recharge-free Proclaim SCS family and the rechargeable Eterna SCS platform. (Source: MassDevice)

First-in-Human Use for Spinal Cord Injury Patients Shows Promising Results

May 15, 2023 - ONWARD Medical has achieved a successful first-in-human use of their ARC-IM Lead, delivering targeted electrical pulses to the spinal cord. The lead's unique design and electrode placement offer potential benefits for blood pressure regulation in individuals with spinal cord injury. (Source: Yahoo Finance)

Smart Earpiece May Accelerate Stroke Recovery by Stimulating Neural Circuits

May 15, 2023 - Researchers from ETH Zurich have developed a smart earpiece that stimulates the vagus nerve to accelerate stroke recovery. The non-invasive system eliminates the need for surgery and promotes neuroplasticity by timing electrical impulses during specific motor actions. A movement sensor tracks progress, and remote monitoring is possible via a smartphone app. The first clinical study is impending. (Source: Today’s Medical Developments)

Transcutaneous Auricular Vagus Nerve Stimulation is a Potential Novel Treatment for Polycystic Ovary Syndrome   

May 12, 2023 - This study targets parasympathetic modulation via non-invasive transcutaneous auricular vagal nerve stimulation (ta-VNS) and suggests that this procedure is promising as a treatment or supplementary treatment for polycystic ovary syndrome (PCOS). (Source: Nature)

Study Indicates PET Imaging Reveals Brain Stimulation's Effects in Coma Patients

May 11, 2023 - A study utilizing PET imaging has shown that trigeminal nerve stimulation (TNS) can increase brain metabolism in key cognitive areas and potentially promote recovery in patients with disorders of consciousness. The findings support the use of TNS as a promising intervention for coma awakening and demonstrate the effectiveness of FDG-PET as an objective evaluation tool in assessing brain function in these patients (Source: Brain Stimulation)

Spinal Cord Stimulation System Receives Expanded FDA Approval for MRI Labeling

May 11, 2023 - Abbott has received expanded FDA MRI labeling for its Eterna pain relief device. (Source: Seeking Alpha)

Implantable Tibial Neuromodulation Therapy for Overactive Bladder Shows Promising Results

May 10, 2023 - OASIS, a 151-patient open-label clinical study demonstrated statistically significant improvement in reduction in urgency urinary incontinence, including urinary urgency and urinary frequency. Results are under review by the FDA. (Source: Yahoo! Finance)

Survey of Parkinson’s Patients Indicated Deep Brain Stimulation Knowledge Gaps

April 27, 2023 - A survey of 52 adults with Parkinson’s Disease revealed knowledge gaps about deep brain stimulation use, including side effects, symptom management, and whether it alters the course of the disease. Improvements in patient education and counseling were recommended. (Source: Healio)

Animal Study Suggests Spinal Cord Stimulation May Improve Peripheral Neuropathy Associated with Cancer Treatment

April 27, 2023 - Findings from a study in rats suggest that spinal cord stimulation may be a promising treatment to reduce peripheral neuropathy and associated pain in cancer patients undergoing active treatment with paclitaxel, a common anti-cancer drug. (Source: Science Direct)

Study Finds External Brain Stimulation Can Condition Brain Activity

April 24, 2023 - A study with 75 participants found that the effects of transcranial magnetic stimulation (TMS) can be triggered by listening to a tone. While TMS effects are generally temporary, classical conditioning through TMS may be useful to extend the effects in various therapeutic applications (Source: Neuroscience News)

Spinal Cord Stimulation System Receives Expanded FDA Approval for MRI Labeling

April 19, 2023 - Neuspera Medical received FDA clearance for its novel implantable spinal cord stimulation system. (Source: Seeking Alpha)

Study Shows Epidural Stimulation Can Help People With Spinal Cord Injuries Regain Ability to Walk

April 19, 2023 - A study has found that epidural stimulation can help people with spinal cord injuries (SCI) regain the ability to walk. All six participants received epidural stimulation and underwent rehabilitation and experienced significant improvements in their walking ability and overall mobility. (Source: Neuroscience News)

Case Series Finds Spinal Cord Stimulation Prevents Autonomic Dysreflexia in Individuals with Spinal Cord Injury

Apr. 19, 2023 - The FDA has granted approval to Biotronik's spinal cord stimulation system (SCS), called Prospera, for pain relief. The device, which uses both burst and tonic stimulation, is intended for the treatment of chronic pain in the back and legs. (Source: MassDevice)

Case Series Finds Spinal Cord Stimulation Prevents Autonomic Dysreflexia in Individuals with Spinal Cord Injury

Apr. 16, 2023 - Spinal cord stimulation (SCS) may be an intervention to mitigate unstable blood pressure following spinal cord injury (SCI). Results of this case series show promising evidence to support epidural SCS to prevent autonomic dysreflexia (AD) episodes during routine bowel procedures. (Source: MDPI)

Article Discusses Potential Benefit of Non-Invasive Brain Stimulation in Neuromodulation Treatment for Alzheimer’s

Apr. 14, 2023 -  This article addresses that the impact of transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) on the blood brain barrier may increase the effectiveness of neuromodulation in Alzheimer’s patients and calls for further investigation. (Source: Nature)

Article on Systematic Review of Brain Stimulation in Upper-Limb Stroke Rehabilitation Indicates Effectiveness

Apr. 14, 2023 - A systematic review of 38 randomised controlled trials (RCTs) was featured in Neuromodulation: Technology at the Neural Interface. Findings indicate transcutaneous vagus nerve stimulation (VNS) and transcranial direct current stimulation (tDCS) were effective in improving upper-limb motor function. (Source: NeuroNews International)

Spinal Cord Stimulator Gains FDA Approval After Restoring Arm Movement After Stroke

Apr. 12, 2023 - Reach Neuro was granted a breakthrough-device designation by the FDA after the device restored arm movement for two patients following partial paralysis after stroke. Patients experienced improved strength, speed, and functionality. (Source: Fierce Biotech)

Non-Invasive Spinal Cord Stimulation Clinical Trial Targets Upper Body Mobility After Spinal Cord Injury 

Apr. 11, 2023 - The first patient was enrolled in a randomized, prospective, multicenter clinical trial to assess the safety and efficacy of ExaStim® Therapy, a non-invasive spinal stimulator in treating spinal cord injury. (Source: Yahoo! Finance)

Experimental Device May Support Low Blood Pressure Due to Spinal Cord Injury

Apr. 10, 2023 - A neuroprosthetic baroflex is an experimental device that stimulates the neurons in the lower lower part of the spine that are involved in blood pressure control. A recent essay in Science suggests this device may notably increase blood pressure and restore hemodynamic stability (Source: HealthDay)

Company Receives Full FDA Approval for Diaphragm Stimulation System

Apr. 6, 2023 - The NeuRx diaphragm stimulation solution has premarket approval from the FDA to help hospitalized patients with spinal cord injuries to breathe more naturally than with a ventilator. This system also has a humanitarian use exemption from the FDA to provide breathing support for people with amyotrophic lateral sclerosis. (Source: Fierce Biotech)

Steering Committee Releases Evidence-Based Consensus Guidelines on Patient Selection and Trial Simulation for Spinal Cord Stimulation

Apr. 4, 2023 - The American Society of Regional Anesthesia and Pain Medicine approved the formation of a steering committee to develop evidence-based guidelines for patient selection and the role of a spinal cord stimulation trial. The results were published in the Regional Anesthesia & Pain Medicine journal. (Source: Newswise)

Article On the Complexities of Chronic Pain Care Mentions Use of Intrathecal Drug Delivery and Spinal Cord Stimulation

Mar. 28, 2023 - An article on chronic pain addresses the gap between pain management research and clinical application, as well as the search for biomarkers for pain, psychological implications, and recent research findings. One patient’s experience with intrathecal drug delivery and spinal cord stimulation is also mentioned, among other treatment methods. (Source: Nature)

Long-Term Spinal Cord Stimulation Shows Improvements in Some Patients with Refractory Angina Pectoris

Mar. 20, 2023 - This study reports on the long-term efficacy and safety of spinal cord stimulation (SCS) as a treatment option for refractory angina pectoris (RAP). Results after a one-year follow-up showed reductions in angina frequency and use of short-acting nitrates, with a low risk of spinal cord stimulator-related complications. (Source: Science Direct)

Study Indicates rTMS Treatments Alter Neural Connectivity Brain-Wide in Treatment-Resistant Depressed Patients 

Mar. 16, 2023 - An American Journal of Psychiatry study of treatment-resistant depressed patients reported widespread acute alterations in functional connectivity beyond the targeted cortical area after one rTMS (repetitive transcranial magnetic stimulation) session. Patients with the most pronounced connectivity changes in session one tended to get more benefit from a 4-week course of therapy. (Source: Brain & Behavior Research Foundation)

Depression Severity was Decoded from Intracranial Neural Activity in a Recent Study

Mar. 16, 2023 - In a study published in Biological Psychiatry, intracranial electrodes were implanted in the prefrontal cortical regions in three human subjects with severe depression and depression severity scores were taken from neural recordings. Reduced depression severity was associated with decreased low-frequency neural activity and increased high-frequency activity. (Source: Neuroscience News)

Study Explored Relationship Between ECAP Thresholds and Behavioral T-levels in Implanted Children with Cochlear Nerve Deficiency 

Mar. 15, 2023 - A study of 29 children diagnosed with cochlear nerve deficiency (CND) who underwent cochlear implantation found a significant correlation between electrically evoked compound action potential (ECAP) thresholds and behavioral-T levels. The results can more efficiently inform the selection of stimulation levels for children who cannot cooperate with behavioral testing. (Source: Scientific Reports) 

Neurostimulation and Neuromodulation Offer New Approaches to Treat Dry Eye

Mar. 7, 2023 - Devices and pharmaceuticals that stimulate the trigeminal nerve have been found to produce real tears that provide relief for ocular surface disease. (Source: Healio)

Company’s FDA Clearance is Expanded for Neuromodulation Armband for Migraine

Mar. 1, 2023 - The Nerivio neuromodulation armband is available by prescription to treat migraine symptoms after onset, and newly expanded FDA clearance approved the device for migraine prevention. (Source: Fierce Biotech)

Study Details Early Vagus Nerve Mapping and Novel Vagus Nerve Stimulation Device

Feb. 28, 2023 - Researchers at the Feinstein Institutes for Medical Research published findings in the journal Brain Stimulation after microscopically mapping more than 100,000 fibers that comprise the vagus nerve. The study addresses how they are connected and what bodily functions they control, and insight into a vagus nerve stimulation (VNS) device that can actively target these fibers. (Source: Neuronews International)

Article Summarizes Spinal Cord Stimulation Study of Stroke Patients with Upper-Limb Paresis

Feb. 20, 2023 - NPR summarizes the publication of a four-week study in Nature Medicine which reports that cervical spinal cord stimulation improved arm and hand movement for two participants with limb paresis years after stroke. The article features the experience of one study participant and the medical team who conducted the study. (Source: NPR)

First-Person Article Details Impact of Deep Brain Stimulation for Parkinson’s

Feb. 20, 2023 -  CBC News New Brunswick host Harry Forestell addresses how deep brain stimulation (DBS) can improve motor function control in some Parkinson’s patients and shares his first-person experience with the procedure, along with a video that demonstrates its effects. (Source: CBC News)

News Column Addresses Bioelectricity and Numerous Applications in Neuromodulation 

Feb. 5, 2023 -  A column about bioelectricity describes transcranial direct current stimulation (tDCS), deep-brain stimulation (DBS), and other potential therapeutic and elective implications of bioelectricity in neuromodulation. (Source: The Guardian)

Video Features Deep Brain Stimulation Patients for Movement Disorders

Feb. 5, 2023 - 60 Minutes Australia featured patients with Parkinson’s and essential tremor (ET) before and after their experience receiving deep brain stimulation (DBS), and addressed the procedure’s potential benefit for a range of movement disorders and other conditions. (Source: 60 Minutes Australia)

Company’s Sacral Neuromodulation System Received FDA Approval for Incontinence

Jan. 31, 2023 -  Axonics’ received FDA approval for its fourth-generation R20 rechargeable sacral neuromodulation system for patients suffering from overactive bladder or fecal incontinence. (Source: MassDevice)

Company’s Spinal Cord Stimulation System Received FDA Approval for Diabetic Peripheral Neuropathy

Jan. 30, 2023 - Abbott’s Proclaim XR spinal cord stimulation (SCS) received FDA clearance for patients to receive low doses of stimulation for diabetic peripheral neuropathy (DPN) symptoms contributing to chronic pain. (Source: Pharmacy Times)

Nerve Stimulation Therapy After Spinal Cord Injury Shows Promise in Animal Studies

Jan. 30, 2023 - Columbia University Vagelos College of Physicians and Surgeons published study findings in the journalBrainthat show promise in animals. If applicable in humans, patients with arm function impairment due to spinal cord injury could regain function as a result of the spinal cord associative plasticity (SCAP) technique. (Source: Technology Networks)

Company Received FDA Clearance for First Neuromodulation Device to Treat Tinnitus

Jan. 30, 2023 - Neuromod Devices’ neurostimulation system for tinnitus – Lenire – received initial FDA clearance. The system takes a two-pronged approach using tones to activate the auditory nerve and mild electrical stimulation of the tongue. (Source: Fierce Biotech)

Article Addresses Spinal Cord Stimulation for Sleep and Chronic Pain

Jan. 30, 2023 - Senior author Julie Pilitsis, M.D., Ph.D., and a team of researchers at Schmidt College of Medicine published a study in Stereotactic and Functional Neurosurgery which established minimally clinical important difference ranges for the insomnia severity index, a tool established to explore the relationship between insomnia and pain. This study revealed associations between sleep and depression but no correlation between sleep and spinal cord stimulation (Source: Florida Atlantic University)

Article Addresses How fMRI Technology May Help Inform Brain Stimulation

Jan. 27, 2023 - Ultrafast fMRI can now capture brain activity at sub-second levels which allows for real-time brain monitoring under simulation conditions. Associate Professor Kai-Hsiang Chuang’s laboratory at the Queensland Brain Institute (QBI) found that brain activity is dependent on one’s state, and that blood signal detected by fMRI may reflect network organization and cell type distribution. (Source: Neuroscience News)

Transcutaneous Auricular Vagus Nerve Stimulation Can Improve Mild Cognitive Impairment

Jan. 27, 2023 - A double blind randomized controlled trial published in Brain Stimulation showed transcutaneous auricular vagus nerve stimulation can improve cognitive performance in patients with mild cognitive impairment (MCI). Evidence shows this technique could prevent or prolong MCI’s development into dementia. (Source: NeuroNews International)