Volunteers for the International Neuromodulation Society have created informational short videos about a number of conditions that may be treated with neuromodulation therapies, and introductory information regarding such therapies.

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Addiction is considered a brain disease, and as understanding evolves through research and clinical investigations, neuromodulation is poised to have a greater influence on addiction treatment.

Cancer Pain

Pain can be associated with cancer during, or after, diagnosis and treatment. Controlling cancer pain can contribute to resiliency and methods may include use of intrathecal drug delivery systems, a type of neuromodulation therapy.

Chronic Mechanical Low Back Pain

Usually mechanical low back pain improves over days to weeks with ice, heat, physical therapy, and medications. If it lasts more than 90 days and becomes chronic, other treatment options may be considered. Among those are neuromodulation using medication or neurostimulation. The latter method is intended to help reactivate muscle control of the lower spine to restore functional stability, in order to decrease pain.

Complex Regional Pain Syndrome

Complex regional pain syndrome is an uncommon nerve disorder with out-of-proportion pain; learn what it is and what some options are in this brief video.


Sacral nerve stimulation may be an option to improve symptoms of certain kinds of constipation.

Depression and Bipolar Disorder

Neuromodulation is a novel approach to depression and bipolar disorder that may be effective in treatment-resistant cases.


Medication-resistant epilepsy may be treated with neurostimulation. Three types of neurostimulation used in epilepsy are vagus nerve stimulation, responsive neurostimulation, and deep brain stimulation.

Essential Tremor

Essential tremor can impact quality of life, and if medication is inadequate or side-effects become intolerable, deep brain stimulation is a type of neuromodulation therapy that can help manage its symptoms.

Persistent Spinal Pain Syndrome Type 2 (Formerly Failed Back Surgery Syndrome - FBSS)

Neuromodulation can be among treatment options for new or persistent pain after spinal surgery for back or leg pain. Since approximately 2020, pain management physicians have advocated using the term "persistent spinal pain syndrome" instead.

Fecal Incontinence

Quality of life takes a toll for people with fecal incontinence who cannot control timing of bowel movements. A minimally invasive procedure, sacral nerve stimulation is a treatment option that has the highest rate of success and lowest complication rate among surgical treatments for the condition.


Gastroparesis, caused by partial paralysis of the stomach, can be caused by neuropathy or other conditions. Electrical stimulation of the gut is subject to research studies as a minimally invasive therapy for this condition.


Refractory headaches do not respond to traditional medical treatment and affect up to 20% of the population. The headaches may include cluster headache, migraine, and occipital neuralgia.

Neuropathic Pain

Chronic neuropathic pain can impact quality of life; when medication, physical therapy, and neurolytic procedures do not provide sufficient relief, neuromodulation may be considered; it disrupts pain signals through targeted stimulation of the nervous system, such as the spinal cord or peripheral nerves.

Parkinson's Disease

Parkinson's disease involves a loss of dopamine, which can be addressed with medication, but as the disease progresses, patients may also consider a deep brain stimulation system to help manage motor symptoms of the disease.

Pelvic Pain

Chronic pelvic pain is a debilitating condition, affecting men and women, that lasts more than six months. Management can be elusive since imaging results are typically normal. However, newer methods, backed by science, offer hope to patients who still suffer.

Post-Amputation Pain

Post-amputation pain is an unpleasant sensation felt in the remaining and/or missing limb following a limb loss surgery.


Spasticity management can involve neuromodulation therapy using an implanted intrathecal drug delivery device.

Urinary Dysfunction

When urinary issues such as overactive bladder or retention are due to faulty signals or nervous system reflexes, neuromodulation using sacral nerve stimulation can be an option to consider, one which is safe, effective, reversible, and avoids major surgery.