2019 News Briefs - International Neuromodulation Society

Earlier News:

New Swiss Center Will Focus on Neurostimulation Technologies to Restore Motor Function

Dec. 5, 2019 - A Swiss initiative is establishing the NeuroRestore Center that draws upon expertise from four partner institutions in neurorehabilitation and neurosurgical implant technologies. The center will be focusing on developing electrical stimulation therapies to help restore motor function in paralyzed patients, as well as in people who have Parkinson's disease or are recovering from stroke. (News-medical.net)

Canadian Startup That Is Developing Noninvasive Neuromodulation for Pelvic-Floor Disorders Raises $10 Million

Dec. 4, 2019 - Toronto-based EBT Medical, Inc. announced raising USD $10 million in Series A financing, which will help the startup to further develop its noninvasive neuromodulation technology for pelvic health disorders. (FinSMEs)

Research News Article Summarizes the State of Bioelectronic Medicine

Dec. 3, 2019 - A news feature about bioelectronic medicine describes the growth and development of interest in the field. (PNAS)

Journal Publications Share Implant Technique for Dorsal Root Ganglion Stimulation

Nov. 22, 2019 - A retrospective case series considers a transgrade technique for dorsal root ganglion stimulation, while a technical note in Pain Practice also addresses the technique. (Pain Physician)

Startup Announces $10 Million in Funding for Spinal Cord Stimulator Development

Dec. 3, 2019 - Micro-Leads Medical, Inc. announced it is receiving up to $10 million in funding from the National Institutes of Health initiative Helping to End Addiction Long-Term (HEAL) and private investors, including milestone payments over several years. The company plans to launch a clinical study of its spinal cord stimulation lead intended to address chronic low-back pain and focal pains of the trunk and extremities. (Digital Journal)

Research Explores Recreating Neural Dynamics in Silicon

Dec. 3, 2019 - Researchers wrote in Nature Communications that they have experimented with trying to recreate neural firing patterns in silicon chips, as a potential future "bionic neuron" that might one day provide therapies for chronic disease through repair of diseased circuits of the central nervous system, for instance, potentially addressing such issues as cardiac arrhyhmia if age or disease causes decoupling of respiratory and cardiac rhythms. (The Guardian)

Study Combines Stroke Rehabilitation and Vagus Nerve Stimulation

Dec. 3, 2019 - A clinical trial in England combined post-stroke physical rehabilitation and stimulation of a branch of the vagus nerve through a clip worn on the ear. (Daily Mail)

Company Announces Canadian MRI Labeling of its Sacral Nerve Stimulation System

Dec. 2, 2019 - Health Canada has approved full-body MRI labeling for the Axonics Modulation Technologies, Inc. sacral neuromodulation system. (BioSpace)

Noninvasive Neurostimulation Device is Subject to a Licensing Agreement in Japan

December 2019 - NeuroSigma, Inc. has entered into an exclusive license agreement with the Japanese pharmaceutical and medical device manufacturer Teijin Ltd. that allows the licensee to market NeuroSigma's external trigeminal nerve stimulation system for treatment of ADHD in Japan. (Neurotech Business Report)

Thin-Film Technology Electrode Cleared by FDA for Temporary Cortical Use

Dec. 2, 2019 - A thin-film, printed-microcircuit, cortical electrode received FDA clearance for up to 30 days of use for recording, monitoring, and stimulation. (NeuroOne)

Article Reports on Impact of Deep Brain Stimulation on Swimming in Some Parkinson's Disease Patients

Nov. 27, 2019 - An article in the Journal of Neurology reported on how deep brain stimulation for Parkinson's disease affected nine patients' ability to swim. (New York Times)

Neurosurgeons Discuss Research Into Deep Brain Stimulation to Address Tinnitus

Nov. 24, 2019 - A University of Toronto student newspaper published an interview with researchers who had published an editorial in the Journal of Neurosurgery about a Phase 1 open-label study of caudate deep brain stimulation for treatment-resistant tinnitus. (The Varsity)

Tool Piloted to Assess Trainees' Surgical Skills in Spinal Cord Stimulation

Nov. 6, 2019 - Clinicians are piloting a surgical skill assessment tool for trainees who are learning to implant spinal cord stimulation systems. (Regional Anesthesia and Pain Medicine)

Neurotechnology Event Includes Recognition of a Leading Neuromodulation Pioneer

November 2019 - Past president of the International Neuromodulation Society Elliot Krames, MD, received a lifetime achievement award at the 2019 Neurotech Leaders Forum. (Neurotech Reports)

Neurostimulation Device Clinical Trial Begins in Patients Experiencing Opioid Withdrawal

Nov. 21, 2019 - Spark Biomedical, Inc. announced patient enrollment has opened in its prospective, double-blind, randomized-control clinical trial of its auricular neurostimulation device for opioid withdrawal relief. (PR Newswire)

Company Announces a U.S. Supply Agreement for Its Recently Approved Device

Nov. 21, 2019 - Axonics Modulation Technologies, Inc. announced it will supply its recently approved sacral neuromodulation system to the University of Tennessee Medical Center as one of the first U.S. centers to offer the device. (Business Wire)

Noninvasive Neurostimulation Company Has Korean Initial Public Offering

Nov. 20, 2019 - Remed, which researches and develops transcranial magnetic stimulation devices, issued an announcement of its plans on the occasion of its initial public offering. The company was reported to anticipate raising between $7.4 million to $8.4 million. (Korea Biomedical Review)

Indian State Health Department Enters Agreement for Advanced Neurological Training That Can Address Movement Disorder

Nov. 20, 2019 - Tamil Nadu's Health Department is entering into a memorandum of understanding with the U.K.'s Kings College Hospital for training in advanced neurological protocols for conditions such as Parkinson's disease. As part of a concurrent awareness campaign, an ophthalmologist with Parkinson's disease suggested deep brain stimulation be brought under the government's comprehensive health insurance. (The Hindu)

Deep Brain Stimulation Effect on Tremor Studied

Nov. 20, 2019 - Physicians used accelerometers in essential tremor patients to quantify therapeutic effects of deep brain stimulation of the ventral intermediate nucleus of the thalamus across multiple parts of the body. (Clinical Neurophysiology)

Review Analyzes Potential Issues in Development of Hardware for Neuroprosthetics

Nov. 20, 2019 - A systemic review seeks to assess evidence potentially relevant to hardware-related complications in the research and development of technologies for restorative neuroengineering and neuroprosthetics. (Neuromodulation: Technology at the Neural Interface)

Journal Article Reports Preclinical Work on a Microsystem Probe to Aid Neuroscience Studies Using Optogenetics and Pharmacology

Nov. 19, 2019 - Scientists report in PNAS they have reproduced optogenetic and phramacological experiments in small animals using a wireless microfluidic probe that is injectable and compatible with near-field communication technology. (Northwestern Medicine)

Data Presented About Effects of Noninvasive Neurostimulation on Eye Dryness

Nov. 18, 2019 - Treatment outcomes presented at the annual meeting of the American Academy of Ophthalmology concerned the effects of noninvasive intranasal neurostimulation on eye dryness, pain intensity, and tear volume. (Healio)

Review Analyzes Safety and Effectiveness Data for Chronic Pain Treatment with Dorsal Root Ganglion Stimulation

Nov. 15, 2019 - A review of one prospective, randomized comparative trial and six prospective, single‐arm, observational studies involving dorsal root ganglion stimulation for chronic pain analyzed pooled outcomes for different pain causes or locations. (Neuromodulation: Technology at the Neural Interface)

Review Presents Noninvasive Brain Stimulation Techniques and Applications

Nov. 15, 2019 - A review summarizes the current state of transcranial direct current stimulation for current or emerging applications in motor rehabilitation or motor learning or neurologic or neuropsychiatric conditions. (Journal of NeuroEngineering and Rehabilitation)

Company Announces FDA Approval for Its Sacral Neurostimulation System

Nov. 14, 2019 - Axonics Modulation Technologies said it has won FDA approval for its sacral neuromodulation system for treatment of overactive bladder and urinary retention. (Mass Device)

Case Series Presents Outcomes of Peripheral Nerve Stimulation for Pain Conditions

Nov. 14, 2019 -  Bioness, Inc. announced publication of a prospective case series about peripheral nerve stimulation for focal mononeuropathy treatment, focusing on such outcomes as pain scores and activity levels. (PR Newswire)

Study Looks at Practice Volumes for Spinal Cord Stimulation for Chronic Pain in Florida

Nov. 11, 2019 - A study examined medical record CPT codes and estimated office-based procedures to evaluate practice volumes for spinal cord stimulation procedures, including revisions and explants, in Florida during 2018. The study authors discuss practice-volume considerations as an aspect of a potential "center of excellence" designation for specific medical services. (Neuromodulation: Technology at the Neural Interface)

Study Explores Potential for Stimulating Deeper Structures with a Cochlear Implant

Nov. 11, 2019 - Researchers studied current spread in individuals who have cochlear implants, with an interest in potentially gaining the ability to target deeper structures with electrical stimulation, including the auditory nerve. (Neuromodulation: Technology at the Neural Interface)

Study: Smoking and Pain Reduction from Neurostimulation Examined

Nov. 11, 2019 - A study of the association between tobacco smoking and neurostimulation effectiveness analyzed outcomes of 420 patients who received spinal cord stimulation for complex regional pain syndrome. The retrospective analysis compared the degree of pain reduction through 12 months in nonsmokers, smokers, and former smokers. (Neuromodulation: Technology at the Neural Interface)

Pilot Study Investigates Vagus Nerve Stimulation for Rheumatoid Arthritis

Nov. 9, 2019 - Safety and efficacy data were presented from a first-in-human, double-blind pilot study of once-daily vagus nerve stimulation in drug-resistant rheumatoid arthritis. (Rheumatology Advisor)

Researchers Pursue a Minimally Invasive Stimulation System Based on an Injectable Electrode Material

Nov. 8, 2019 - Researchers have published preclinical data from their collaboration to create externally powered neurostimulation systems by injecting fluid electrode material that cures in place. The project recently received a $2.1 million grant from a National Institutes of Health to support development of a non-opioid alternative to treat chronic back pain. The injected stimulator elements would operate with power from a transcutaneous electrical stimulation unit. (University of Wisconsin-Madison)

Study Examines Reasons for Spinal Cord Stimulation Removal

Nov. 8, 2019 - Researchers published a study analyzing the reasons 129 patients had spinal cord stimulation systems removed between 2005-2013. (Medical Xpress)

Publication Presents Functional Electrical Stimulation for Hand Control After Paralysis

Nov. 7, 2019 - Researchers published results of using closed-loop neurostimulation and textile-based electrodes to facilitate finger movement and regulation of grasp force in individuals with quadriplegia. (PR Newswire)

Medical Engineering Company Announces €13 million Investment, Future Plans

Nov. 7, 2019 - CorTec GmbH announced closing a round of €13 million in investment funding, and plans to open a subsidiary in the U.S. (CorTec)

One-Year Follow-Up Reported in Amputees Using Peripheral Nerve Stimulation

Nov. 6, 2019 - In a meeting abstract, investigators report 12-month follow-up in a placebo-controlled crossover trial involving a two-month course of percutaneous peripheral nerve stimulation for chronic pain in amputees. (News-medical.net)

Study Analyzes Data About Opioid Use One Year After Starting Spinal Cord Stimulation

Nov. 6, 2019 - A retrospective study presented at the International Neuromodulation Society 14th World Congress examined reduction in opioid use one year after patients began spinal cord stimulation. (Pain Medicine News)

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News Feature Describes Pain Relief from Spinal Cord Stimulation in British Columbia

Nov. 5, 2019 - An article about a chronic pain patient who recently found relief via spinal cord stimulation (SCS) notes that the government in British Columbia, Canada funds 28 SCS implants a year. (Vancouver Sun)

Article Surveys Interventions for Medication-Resistant Head and Face Pain

Nov. 7, 2019 - An article summarizes neurosurgical techniques, including implanted neurostimulators, for patients with medication-resistant chronic head for face pain syndromes such as trigeminal neuralgia, cluster headache, and migraine. (Clinical Pain Advisor)

Company Announces FDA Approval of Spinal Cord Stimulation System

Nov. 5, 2019 - Nevro Corp. announced it has received FDA approval for a spinal cord stimulation system designed to provide an array of waveforms. (PR Newswire)

Company Announces First Commercial Implantation of Sacral Neuromodulator

Nov. 4, 2019 - Axonics announced the first U.S.-based implantation of its sacral neuromodulation system outside of a clinical study, following its FDA approval in September 2019. The device was implanted in a patient to treat urinary and bowel dysfunction. (NeuroNews)

Home-Use Noninvasive Brain Stimulation Headset for Depression Therapy Launched in Europe

Oct. 31, 2019 - Flow Neuroscience has launched a transcranial direct current stimulation headset for use at home in Europe to treat depression. (New Scientist)

Grant Will Fund Research Into Neurostimulation Electrode to Treat Chronic Pain

Oct. 31, 2019 - Neuronoff, Inc. announced a $2.2 million grant from the National Institutes of Health Helping to End Addiction Long-Term (HEAL) initiative to test an injectable metal electrode to treat chronic back pain through stimulation of the dorsal root ganglion. (Business Wire)

Company Releases Smart Phone-Based Patient Programmer for Deep Brain Stimulation Systems

Oct. 30, 2019 - Medtronic has launched a smart phone patient programmer for end-users to manage deep brain stimulation therapy systems. (Fierce Biotech)

MRI-Trained Algorithms Guide Deep Brain Stimulation Surgery of Movement Disorder Patients

Oct. 30, 2019 - Researchers published results in two patients who received deep brain stimulation for movement disorder guided by image-based neurosurgical planning that was developed using deep-learning algorithms from MRIs of 102 patients. (Korea Biomedical Review)

Israeli Company Plans Pilot Study of Neurostimulation for Dry Eye

Oct. 27, 2019 - Epitech Mag Ltd. of Israel is sponsoring a sham-controlled pilot study of an "ocular magnetic neurostimulation system" for severe dry eye disease. (Trial Bulletin)

Spin-out Neuromodulation Company Targeting Migraine Raises $33 Million in Series A Financing

Oct. 25, 2019 - ShiraTronics, Inc., a Brooklyn Park, Minnesota company spun out of the Irish medical device accelerator NuXcel, announced it has raised $33 million in Series A financing. The company is developing neuromodulation technology to potentially treat migraine headaches. (PR Newswire)

Article Presents Neuromodulation for Childhood Motility Disorders

Oct. 10, 2019 - An article about treatments for motility and gastrointestinal disorders in children discusses four neuromodulation therapies, saying neuromodulation has generated "much excitement in the field of neurogastroenterology". (Pediatrics Nationwide)

Company Launches Second Intrathecal Pump Following FDA Approval

Oct. 25, 2019 - Flowonix Medical announced FDA approval and launch of its Prometra II programmable intrathecal drug delivery device. (Drug Delivery Business News)

Review Summarizes Neuromodulation Therapies that Might Aid Hemorrhagic Shock

Oct. 25, 2019 - A review summarizes studies about potential interventions that could provide hemorrhage control, including trigeminal nerve stimulation, vagus nerve stimulation, phrenic nerve stimulation and electroacupuncture. (BioSpace)

Neuromodulation Considered a Top Innovation

Oct. 24, 2019 - A list of top 10 medical innovations for 2020 by the Cleveland Clinic includes closed-loop spinal cord stimulation, citing an article in Neuromodulation: Technology at the Neural Interface, whose authors include one from the Cleveland Clinic. (HealthLeaders)

Article Highlights Recent Developments in Electrical Stimulation Therapies for Diseases and Chronic Conditions

Oct. 24, 2019 - A news feature covers how advances in bioengineering and neurology are contributing to R&D programs in using electrical stimulation of nerves to affect metabolic and immune responses in order to regulate organ function in a number of conditions. According to the article, the research-and-development firm Galvani Bioelectronics expects to enter a device into safety and efficacy trials in humans in a "couple of years". (Time)

Clinical Trial Funded for Studying Spinal Cord Stimulation as a Potential Way to Reduce Falls in Advanced Parkinson's Disease

Oct. 23, 2019 - Clinicians in London will undertake a small study of spinal cord stimulation in patients with advanced Parkinson's disease, to study its effect on frequency of falls. (Mirage News)

Paper Presents Outcomes of MRI-Guided Lead Placement in Dystonia Patients

Oct. 11, 2019 - A team of co-authors published their inquiry into accuracy and clinical outcomes in dystonia patients who were implanted with deep brain stimulation systems using intraoperative MRI-guided lead placement. (Journal of Neurosurgery)

Study Assesses Neurostimulation for Alleviating ADHD Symptoms in Children

Oct. 22, 2019 - A blinded, sham-controlled trial of trigeminal nerve stimulation in children with attention-deficit/hyperactivity disorder (ADHD) was presented at the American Academy of Child & Adolescent Psychiatry 66th Annual Meeting. (Medscape)

Noninvasive Stimulation Device Studied in Chronic Pain Patients

Oct. 22, 2019 - An article discusses a long-term, prospective study of chronic pain patients who used an over-the-counter device that delivers electromagnetic field pulsed shortwave stimulation. (Medscape)

Demonstration of Brain-Machine Interface Shows Movement of Two Robotic Arms

Oct. 22, 2019 - A video shows a disabled volunteer using a brain-machine interface to control two robotic arms in a research project at Johns Hopkins University. The robotic arms were developed as modular prosthetic limbs for the U.S. Defense Advanced Projects Research Agency and include sensors that might help provide some tactile sensations. (Medgadget)

Segment Features Research into Neurostimulation to Improve Memory, Cognitive Function

Oct. 22, 2019 - A journalist produced a segment about trying out a transcranial alternating current brain stimulation system overnight in order to observe any improvement in a computer-simulated task that calls for spotting and responding to visual cues. The federally funded research is being conducted at the University of New Mexico as a project to help sharpen focus and performance of military personnel. (KCRW)

Business Column Covers Spinal Cord Injury Technology Development Plans

Oct. 22, 2019 - An analysis looks at the announcement that GTX medical BV and NeuroRecovery Technologies have merged to develop neurostimulation technologies for restoration of movement after spinal cord injury. The news feature covers current and prospective investment and the potential market. (FirstWord MedTech)

Companies Merge, Pursue Neurostimulation Therapies for Spinal Cord Injury Patients

Oct. 22, 2019 - GTX medical BV has merged with NeuroRecovery Technologies Inc. The merged company, GTX medical BV, is developing a spinal cord stimulation (SCS) system with motion feedback, targeted epidural spine stimulation, to help restore mobility to people with spinal cord injury. In addition, the company is developing transcutaneous SCS for helping restore upper limb movement and hand function.  (Business Wire)

Study Explores Using Neurostimulation to Provide Sensory Precept in Amputees

Oct. 22, 2019 - Researchers studied using epidural spinal cord stimulation to evoke sensory precepts in amputees. (MedRxiv)

Company Raises Funds to Market Electrical Stimulator for Essential Tremor

Oct. 22, 2019 - Cala Health announced it has raised $50 million in Series C financing to help support commercial launch of its wearable electrical stimulation device for hand tremor, which recently received FDA clearance and is available by prescription for patients with essential tremor. (Xconomy)

U.S. BRAIN Initiative Grants More Than $424 Million in Research Funds

Oct. 18, 2019 - The National Institutes of Health announced it has funded more than 180 new research investigations through the BRAIN Initiative (Brain Research through Advancing Innovative Neurotechnologies). The 2019 budget for the program totals more than $424 million. The projects include studies of neural circuits, research into glia, tests of neuromodulation approaches to regaining dexterity after stroke, and projects to help paralyzed people communicate. (National Institutes of Health)

Grant Will Fund Study of Neurostimulation to Address Opioid Withdrawal Symptoms in Infants

Oct. 18, 2019- Spark Biomedical, Inc. announced it has received a grant of $217, 690 from the National Institutes of Health HEAL Initiative to support a clinical study of its neurostimulation system to relieve opioid withdrawal symptoms in infants born with neonatal abstinence syndrome. (PR Newswire)

Research Program Will Focus on "Intelligent Bio-Interfaces"

Oct. 17, 2019 - The U.S. Defense Advanced Projects Research Agency announced a new five-year research program to develop technologies, including smart and adaptive neural interfaces, to help improve functional recovery following spine injury. (DARPA)

Study Investigates External Neurostimulation for Pain in Children with Irritable Bowel Syndrome

Oct. 16, 2019 - A study investigated neurostimulation to the external ear to potentially reduce pain and improve well-being in children with irritable bowel syndrome. The auricular stimulation was delivered through percutaneous electrical nerve field stimulation. (Healio)

Paper Reviews Studies of Noninvasive Brain Stimulation for Migraine

Oct. 15, 2019 - A systemic review and meta-analysis of nine studies summarizes evidence about whether the intensity and frequency of migraine attacks may be decreased by noninvasive brain stimulation of the motor cortex. (Neurology Advisor)

Teenager with Tourette Syndrome Turns to Deep Brain Stimulation

Oct. 15, 2019 - A 17-year-old student who has Tourette syndrome gave a public talk about his experience, which includes pursuing access to deep brain stimulation to potentially address bothersome symptoms. (Iowa State Daily)

Infectious Disease Article Focuses on Approaches to Spinal Cord Stimulator Implants

Oct. 9, 2019 - A team of doctors write about approaches to infection that may arise from implantation of spinal cord stimulation systems, including prevention, diagnosis, and management. (Clinical Infectious Diseases)

Review Considers Intrathecal Drug Choices

Oct. 7, 2019 - A review summarizes research and opinion about the choice of intrathecal drugs in the treatment of neuropathic pain. (Expert Review of Clinical Pharmacology)

Paper Examines Changes in Opioid Use Following Intrathecal Drug Delivery

Oct. 11, 2019 - A study evaluated systemic opioid use before and after the start of intrathecal drug therapy in patients with chronic, noncancer pain, through a retrospective cohort analysis of administrative claims data from 2011 to 2016. (Neuromodulation: Technology at the Neural Interface)

Analysis Evaluates Patient Characteristics and Opioid Consumption After Spinal Cord Stimulation

Oct. 10, 2019 - A team of authors analyzed private health insurance claims for chronic pain patients who had been treated with opioids and received spinal cord stimulation (SCS) therapy between 2003 and 2014, seeking characteristics that might predict reduced opioid consumption following SCS. (Neuromodulation: Technology at the Neural Interface)

Report: Neurosurgical Team Resolves Apparent Stimulation Side Effect in Parkinson's Disease Patient

Oct. 10, 2019 - A neurosurgical team reports on resolving an apparent side-effect of a deep brain stimulation system that was implanted to help relieve motor symptoms of Parkinson's disease. (Stereotactic and Functional Neurosurgery)

Authors Summarize Published Data on Neurostimulation for Chronic Pancreatitis Pain

Oct. 8, 2019 - A review of seven studies, encompassing 31 patients, summarizes published data about effectiveness and complications of spinal cord stimulation for management of pain associated with chronic pancreatitis. (Neuromodulation: Technology at the Neural Interface)

Neuromodulation is Among University's Projects Receiving Over $40 Million from a U.S. Opioid-Crisis Research Funding Initiative

Oct. 10, 2019 - Ten research projects at the University of California, San Francisco that received more than $40 million in grant funding, total, from the National Institute of Health's Helping to End Addiction Long-term (HEAL) Initiative include a study into improving deep brain stimulation for chronic pain, which received $7.56 million. (University of California, San Francisco)

Article Considers Competition in the Sacral Neuromodulation Market

Oct. 8, 2019 - An article looks at perspectives regarding technical developments and competition within the sacral neuromodulation market. (MD+DI)

Review Looks at Opioid-Sparing Effects for One Type of Spinal Cord Stimulation

Oct. 2, 2019 - A review examines reduction of mean daily dose of opioids in patients treated with 10 kHz spinal cord stimulation for chronic pain. (Annals of the New York Academy of Sciences)

Grant Supports Neurotechnology Research to Help Restore Function Following Spinal Injury

Oct. 3, 2019 - A $6.3 million grant from the U.S. Defense Advanced Research Projects Agency will fund a project led out of Brown University to develop a spinal interface intended to help restore limb control and bladder control to people with spinal cord injuries. The system is being designed to record signals traveling down the spinal cord from above an injury site, and use those to drive electrical stimulation below the injury. For an artificial intelligence aspect of the project, the researchers are collaborating with Intel. (EurekAlert)

Noninvasive Vagus Nerve Stimulation Studied in Migraineurs

Oct. 8, 2019 - A randomized, double-blind, sham-controlled, phase 3 study assessed the efficacy and safety of noninvasive vagus nerve stimulation to prevent episodic migraines. (Neurology Advisor)

Study Examines Considerations for Body-Worn Functional Electrical Stimulation Assistive Technology

Oct. 8, 2019 - Researchers published a qualitative study involving potential end-users and clinicians to optimize development of garments that might provide functional electrical stimulation for users paralyzed by stroke or spinal cord injury. (Disability and Rehabilitation: Assistive Technology)

Review: Evolution of Neurostimulation to Treat Dry Eye Disease

September 2019 - An article reviews evolution of neurostimulation for treatment of dry eye disease. (Ophthalmology Advisor)

Research Points to Role of Astrocytes in Modulating Neuronal Activity

Oct. 8, 2019 - A study of neuronal pathways and synaptic strength using focused ultrasound stimulation of the motor cortex of mice suggested the presence of a sensitive mechano-channel for calcium in astrocytes, but not neurons. (EurekAlert)

Company Seeks FDA Approval for Rechargeable Sacral Neuromodulation System

Oct. 7, 2019 - Medtronic has submitted for FDA approval a rechargeable version of its sacral neuromodulation system. (Fierce Biotech)

Clinical Trial Results Presented for Cardiac Neuromodulation System for Hypertension

Oct. 7, 2019 - Orchestra BioMed announced results of its double-blind randomized study of cardiac neuromodulation therapy system for hypertension, at a late-breaking session at the Transcatheter Cardiovascular Therapeutics scientific symposium. (Cardiac Rhythm News)

Pivotal Study Data Presented for Rechargeable Sacral Neuromodulation System

Oct. 7, 2019 - Twelve-month data from a pivotal study of the Axonics' rechargeable sacral neuromodulation system in patients with urinary urgency incontinence were presented at a joint scientific meeting of the American Urogynecologic Society and the International Urogynecological Association. (NeuroNews)

Long-Term Data Published in Study of Deep Brain Stimulation for Treatment-Resistant Depression

Oct. 4, 2019 - The American Journal of Psychiatry published data from 4-8 years of follow-up of 28 patients who were enrolled in an open-label trial of deep brain stimulation to the subcallosal cingulate for treatment-resistant depression. (Science Daily)

Study Examines Characteristics of Parkinson's Disease Patients Receiving Deep Brain Stimulation

Oct. 4, 2019 - A study found a gender imbalance among Parkinson's disease patients who underwent deep brain stimulation for tremor. (AJMC)

Data Presented About Spinal Cord Stimulation Combined with Use of Opioids and Sedatives

Oct. 2, 2019 - Data were presented at the American Academy of Pain Medicine annual meeting about spinal cord stimulation patients and concurrent use of opioids with benzodiazepines and/or muscle relaxants. The research investigated whether the concomitant use of those drugs impacted the efficacy of spinal cord stimulation. (Pain Medicine News)

Research Project Envisions Wireless Endovascular Neurostimulators for Peripheral or Central Nervous System Targets

Oct. 1, 2019 - Collaborators at research institutions in Texas are using a grant from the National Institutes of Health Helping to End Addiction Long-term Initiative to develop wirelessly powered nerve stimulators to be delivered on stents through blood vessels adjacent to targets in the central or peripheral nervous system to treat chronic pain or other conditions. The device would be powered and controlled by an externally worn magnetic-field generator. (Baylor College of Medicine)

Device Maker Submits Regulatory Application to the FDA

Oct. 1, 2019 - Mainstay Medical said the FDA has accepted filing of its application for premarket approval of its implantable device for chronic disabling lower back pain, and is expected to reach a decision on approval around the end of 2020. (The Irish Times)

Company Starts Study Centered on a Coverage Determination

Sept. 30, 2019 - As part of the U.S. Centers for Medicare & Medicaid Services's Coverage with Evidence Development Program, LivaNova has enrolled its first patient in a study evaluating its vagus nerve stimulation system in treatment resistant depression. (MD+DI)

Paper Reports Programming Approach to Deep Brain Stimulation

Sept. 30, 2019 - Physicians in Switzerland report they anatomically and clinically characterized dyskinesias elicited by deep brain stimulation in Parkinson's disease patients and then tested if those contacts could be used to optimize stimulation programming and decrease bradykinesias. (Movement Disorders)

Study Combines Noninvasive Neurostimulation and Physical Therapy After Brain Injury

Sept. 27, 2019 - Researchers in Wisconsin studied both high- and low-frequency noninvasive translingual neurostimulation plus targeted physical therapy to treat chronic balance and gait deficits due to mild-to-moderate traumatic brain injury. (Archives of Rehabilitation Research and Clinical Translation)

Neurosurgeons Investigate Deep Brain Stimulation Location and Non-Motor Parkinson's Disease Symptoms

Sept. 23, 2019 - An international group of authors used probabilistic mapping data from a prospective, open-label, multicenter study to investigate how the location of subthalamic nucleus deep brain stimulation influenced non-motor symptoms in patients with Parkinson's disease. (Brain)

Developer of Closed-Loop Deep Brain Stimulation System Raises Private Financing

Sept. 26, 2019 - A medical device spin-off in Milan, Newronika, is developing a closed-loop system for deep brain stimulation and has raised 8.4 million euros in Series A financing. The company said the financing will help support an initial clinical study in Parkinson's disease, and pursuit of CE mark in Europe, as well as application to the FDA for a clinical study of safety and effectiveness. (Yahoo Finance!)

Analysis Details Outcomes of Hypoglossal Nerve Stimulation in Obstructive Sleep Apnea

Sept. 26, 2019 - Researchers published a study of demographic factors that may be associated with greater improvements in outcomes of hypoglossal nerve stimulation in obstructive sleep apnea. The study pooled data from a postmarket approval study in Germany, an international registry, and a retrospective cohort study from two U.S. sites. (Medical Dialogues)

Physicians Study the Effect of a Deep Brain Stimulation Target on Cardiovascular Response

Sept. 6, 2019 - Pedunculopontine nucleus (PPN) deep brain stimulation may improve gait disorders in Parkinson's disease and change autonomic performance. Since positional hypotension can be a debilitating feature of Parkinson's disease, physicians investigated the effect of PPN stimulation on blood pressure and cardiovascular response to an autonomic challenge. They reasoned the stimulation may alter neural control of baroreflex activation. (Clinical Autonomic Research)

Company Announces FDA Approval of a Low-Dose Spinal Cord Stimulation System

Sept. 26, 2019 - Abbott announced FDA approval of its non-recharageable neurostimulation system that delivers a burst waveform. The system is under review for CE mark approval in Europe. (Mass Device)

National Institutes of Health Grant Will Support Research Into a Novel Chronic-Pain Neurostimulator Material

Sept. 26, 2019 - An investigation of a self-curing electrode for dorsal root ganglion stimulation to treat chronic pain will be led out of the University of Wisconsin with more than $2 million in grant funding from the National Institutes of Health's Helping to End Addiction Long-term Initiative. The investigation will test a composite electrode material designed to be injected in liquid form and solidify in place. (University of Wisconsin - Madison)

Preliminary Study of Noninvasive Vagus Nerve Stimulation for Vestibular Migraine

Sept. 25, 2019 - A preliminary study of noninvasive vagus nerve stimulation evaluated the treatment's effects on dizziness during vestibular migraine attacks, and, in some patients, between attacks. (Health Day)

Brain Stimulation Study Seeks to Clarify Anxiety-Linked Performance Mechanisms

Sept. 25, 2019 - A research collaboration used suppressive effects of transcranial magnetic stimulation to investigate the link between activity in the dorsal anterior cingulate cortex and anxiety-induced degradation in physical performance. The findings distinguished between participants who learned repetitive motor skills in discrete parts or those who learned in one whole sequence - a distinction important to the self-focus theory about mental processing and performance. (Medical Xpress)

Brain Implant Provides Visual Cues for Individuals Who Were Blinded

Sept. 19, 2019 - A profile of a patient describes the vision achieved with a visual prosthesis for people who have lost their vision. The prosthesis permits perception of movement and light and dark areas in the field of vision. The device combines sunglasses with an integrated video camera that wirelessly communicates with an electrode array implanted above the brain's visual cortex. (Medical Express)

Physicians Report Phase 1 Trial of Deep Brain Stimulation for Treatment-Resistant Tinnitus

Sept. 24, 2019 - Researchers published a Phase 1 trial of deep brain stimulation that targeted the caudate for treatment-resistant tinnitus. The prospective trial enrolled five patients who underwent several weeks of setting adjustment followed by 24 weeks of stimulation at the optimal setting. (EurekAlert)

Studies Test Intranasal Tear Stimulator for Dry Eyes

Sept. 19, 2019 - A paper reports results of two studies that investigated improvement of dry eye symptoms through intranasal tear stimulation. The studies were conducted in a controlled adverse environment meant to replicate environmental challenges. (The Ocular Surface)

Review: Transcranial Magnetic Stimulation for Anxiety

Sept. 23, 2019 - An article surveys the scientific literature on transcranial magnetic stimulation for anxiety. (Dove Press)

First Patient Implant Announced for Company's Brain-Machine Interface Device

Sept. 20, 2019 - Synchron announced implantation of the first patient with its brain-machine interface device, which has an electrode that is threaded like a stent through an artery to sense electrical activity in the motor cortex using electrocoricography. The company is endeavoring to develop the device as a way for people with paralysis to communicate through directing the brain-machine interface to create text messages. (Fierce Biotech)

News Coverage Features Neuromodulation for Pain in Capital of Saskatchewan, Canada

Sept. 20, 2019 - An article about access to spinal cord stimulation in Regina, Saskatchewan, Canada, encourages awareness among referrers and patients about the treatment and about the influence of wait times on outcomes. (Global News)

Presentation: Deep Transcranial Magnetic Stimulation for Obsessive Compulsive Disorder

Sept. 20, 2019 - A presentation at a European conference about applied brain research, ECNP 2019, covered data from a randomized, sham-controlled, double-blind clinical trial of high-frequency deep transcranial magnetic stimulation for obsessive compulsive disorder. The trial's stimulation targets were the anterior cingulate cortex and medial prefrontal cortex. (Clinical Psychiatry News)

Deep Brain Stimulation Outpatient Service Opens in Metropolitan Region of Southern India

Sept. 19, 2019 - A Bengaluru-based hospital will establish a monthly outpatient clinic for deep brain stimulation to serve people in the area with Parkinson's disease. (Deccan Herald)

Registry Tracks Outcomes of Intrathecal Drug Delivery in Cancer Pain

Sept. 18, 2019 - An analysis presents prospective data from a multicenter product surveillance registry that began adding patient-reported outcomes of intrathecal drug delivery for cancer pain in 2013. (Anesthesia & Analgesia)

nd aid in anticipating near-term and longer-term outcomes. (Journal Summaries in Neurology)

TV News Presents Treatment of Chronic Pain with Noninvasive Brain Stimulation

Sept. 19, 2019 - A television segment presents treatment with transcranial magnetic stimulation for chronic neuropathic pain. (CBS New York)

Retrospective Analysis Focuses on Lower Voltage Sacral Neuromodulation Test Phase for Painful Bladder Indications

Sept. 12, 2019 - A retrospective review of patients who received sacral neuromodulation for medically recalcitrant interstitial cystitis or bladder pain syndrome explored the clinical outcomes from lower motor voltage during stage 1. (Uro Today)

Pilot Study: Simultaneous Stimulation of Two Brain Targets to Treat Freezing of Gait in Parkinson's Disease

Sept. 19, 2019 - Physicians in Spain have published an approach to use dual targeting of deep brain stimulation to treat freezing of gait in Parkinson's disease. The approach uses normal, high frequency stimulation of around 130 Hz to the subthalamic nucleus, and a low frequency stimulation of around 60 Hz to the substantia nigra pars reticulata. (Parkinson's Life)

Authors Examine Geographic Distribution of Some Commercial Neuromodulation Implant Procedures

Sept. 17, 2019 - With data from two neuromodulation companies, neurological surgeons published in an open-access journal an analysis of neuromodulation implants by county and population that occurred near the time of the last U.S. Census. Their analysis included vagus nerve stimulators, but not deep brain stimulation systems. (Cureus)

Emerging Neuromodulation Approaches to Treat Heart Rhythm Disorders

August 2019 - A review looks at the state of art in using neuromodulation of the autonomic nervous system to treat heart rhythm disorders. (JACC: Basic to Translational Science)

Research into Creating Neuromodulatory Effects Without Direct Brain Stimulation

Sept. 18, 2019 - A physical rehabilitation specialist writes about his presentation this year to the International Neuromodulation Society 14th World Congress about the potential of different technologies to create neuromodulatory effects without direct stimulation of the brain. (NeuroNews)

Review: Emerging Deep Brain Stimulation Technologies

Sept. 2, 2019 - In a review article on emerging deep brain stimulation technologies, the authors mention development of techniques focusing on "interaction with disease circuits through complementary, spatially and temporally specific approaches." (Nature Biotechnology)

Algorithm Development for Closed-Loop Deep Brain Stimulation in Parkinson's Disease

Sept. 13, 2019 - Researchers used data stream mining to calculate https://www.sciencedirect.com/science/article/pii/S0957417419301290 when to switch on on-demand, closed-loop, deep brain stimulation in Parkinson's disease, based on the degree of neural synchronization. (Madri+d)

Review Discusses Genetic Screening as a Potential Tool in Patient Selection for Deep Brain Stimulation in Parkinson's Disease

Sept. 6, 2019 - A review summarizes studies of deep brain stimulation and genetic characterization in Parkinson's Disease. (npj Parkinson's Disease)

Spinal Cord Stimulator Company Announces CE Mark Approval and Commercial Launch in Europe

Sept. 16, 2019 - Saluda Medical announced CE Mark approval and commercial launch in Europe of its closed-loop spinal cord stimulation system, with the first commercial implants completed in the Netherlands. (PR Newswire)

Facility in India Has Added Noninvasive Brain Stimulation Services for Psychiatric Conditions

Sept. 13, 2019 - A tertiary care medical and research institute in Northern India has begun offering repetitive transcranial magnetic stimulation and transcranial direct current stimulation in its psychiatry department. (Hindustan Times)

Article Profiles Dystonia Patient Who Received Deep Brain Stimulation

Sept. 11, 2019 - A man with rare generalized dystonia received a deep brain stimulation system in the UK, which has improved his quality of life. (Yorkshire Post)

Company Announces Start of Deep Brain Stimulation Study in Mild Alzheimer's Disease

Sept. 11, 2019 - Functional Neuromodulation announced it has begun a randomized, controlled trial of deep brain stimulation to the fornix in patients aged 65 or older with Alzheimer's disease. The ADvance II safety and efficacy study will enroll up to 210 patients in the United States, Canada and Germany. (Mass Device)

FDA Issues Approval for Sacral Neurostimulator to Treat Fecal Incontinence

Sept. 9, 2019 - Axonics Modulation Technologies announced FDA approval of its rechargeable sacral neuromodulation implant to treat fecal incontinence. An additional application for overactive bladder and urinary retention is still under review. The company anticipated last week receiving a decision about the applications this quarter. (Fierce Biotech)

Team Publishes Findings from Incorporating Sensory Feedback into Prostheses for Leg Amputees

Sept. 9, 2019 - A research team investigated effects on walking speed, fatigue, and phantom limb pain from providing sensory feedback during use of a prosthetic leg. (Nature Medicine)

Research Evaluates Closed-Loop Neural Stimulation for Chronic Pain

Sept. 9, 2019 - An article recaps a scientific presentation from the International Neuromodulation Society 14th World Congress on the clinical utility of evoked compound action potentials in neurostimulation therapy for chronic pain. (NeuroNews)

Researchers Study Association Between Pain Scores During Neurostimulation Trial and After Permanent Implant

Sept. 6, 2019 - A team of researchers has published their investigation into the association between pain scores during trial spinal cord stimulation implantation and pain reduction following permanent implant. (Neuromodulation: Technology at the Neural Interface)

Researchers Evaluate Therapy Habituation with Dorsal Root Ganglion Stimulation vs. Spinal Cord Stimulation

Sept. 5, 2019 - A sub-study compared therapy habituation over 12 months in patients receiving either dorsal root ganglion stimulation or spinal cord stimulation for complex regional pain syndrome. (The Journal of Pain)

CE Mark Approval Announced for Neurostimulator for Hypertension

Sept. 5, 2019 - Orchestra BioMed, Inc. announced it received CE mark approval for its implantable system that is designed to both lower blood pressure and modulate the autonomic nervous system in addition to serving as a cardiac pacemaker. (Cardiovascular Business)

A Column About Disruptive Innovation in Neuromodulation Examines the Effects of Social Media on Communication

Aug. 30, 2019 - A column on social media and neuromodulation addresses issues, concerns, and opportunities presented when sharing content about medical care. (NeuroNews)

Study Examines Role of Brain's White Matter in Noninvasive Brain Stimulation

Aug. 30, 2019 - Researchers in the UK compared healthy patients with those recovering from moderate or severe traumatic brain injury to study effects of white matter connectivity on their response to noninvasive electrical brain stimulation. (Tech Explorist)

Enrollment Complete in Clinical Trial of Neurostimulation for Painful Diabetic Neuropathy

Aug. 29, 2019 - Nevro announced completion of patient enrollment in a prospective multicenter randomized controlled trial of its spinal cord stimulation device in the treatment of painful diabetic neuropathy. (NeuroNews)

Clinical Trial Results Presented in Evaluation of Anatomical vs. Targeted Lead Placement

Aug. 28, 2019 - Results were presented from a prospective multicenter trial that compared anatomical and targeted placement of trial leads for spinal cord stimulation. (NeuroNews)

Noninvasive Brain Stimulation Investigated During Upper-Limb Rehabilitation Following Spinal Injury

Aug. 26, 2019 - With funding from the U.S. Department of Defense Congressionally Directed Medical Research Programs, three centers are testing the safety, feasibility and efficacy of pairing transcranial direct current stimulation with exercise therapies to improve upper limb function following cervical incomplete spinal cord injury. (EurekAlert)

Neurological Treatment Offered in Canada Using Neurostimulation and Physiotherapy

Aug. 26, 2019 - Three centers in Canada are offering neurological treatment that combines several weeks of intensive daily physiotherapy combined with neurostimulation intended to encourage neuroplastic new neural connections. The portable neurostimulator device sits on the tongue. (The Star)

MRI Labelling Announced for Deep Brain Stimulation System

Aug. 21, 2019 - Boston Scientific, Inc. announced FDA approval for MRI labeling of its Vercise Gevia deep-brain stimulation device and companion Cartesia directional lead, allowing them to be used during full-body 1.5-Tesla scans. (Mass Device)

Early Experience with New Generation Deep Brain Stimulation Leads

Aug. 21, 2019 - Julie Pilitsis, MD, PhD, and colleagues have published about early experience with new generation deep brain stimulation leads, sharing observations about the therapeutic window observed in a series of patients with Parkinson's disease or essential tremor. (Neuromodulation: Technology at the Neural Interface)

Article Reports Memory Flashbacks in Some Alzhemier's Patients Receiving Investigational Brain Stimulation

Aug. 21, 2019 - Researchers studying deep brain stimulation targeting the fornix in patients with Alzheimer's disease reported some experienced memory flashbacks. (HealthDay)

Article Reports on Neurostimulation for Occipital Neuralgia

Aug. 21, 2019 - A case series and literature review reports on high cervical spinal cord stimulation for occipital neuralgia. (Journal of Pain Research)

Researchers Seek to Determine Effect of Deep Brain Stimulation on Dopamine Levels

Aug. 20, 2019 - Researchers used PET scanning to look for signs of changing dopamine levels in the brains of Parkinson's disease patients who were receiving deep brain stimulation therapy. (Newswise)

Company Offers Consumer Device to Provide Transcranial Alternating Current Stimulation to the Prefrontal Cortex

Aug. 20, 2019 - A consumer device that provides noninvasive transcranial aternating current stimulation to the prefrontal cortex is being marketed to adults aged 40 and older. (Digital Journal)

Company Event Unveils Plans and Directions for Brain Interface Technology

July 2019 - A launch event for privately held Neuralink, which is pursuing advanced neural recording and stimulation in the brain, presented development of a robotic neurosurgical system and wireless, multichannel chip for neural spike detection and stimulation, as well as revealing some relationships with other neurotech firms and research institutions. (Neurotech Business Report)

Heart-Failure Device Receives FDA Approval

Aug. 16, 2019 - The FDA approved CVRx's Barostim Neo, an implantable device that stimulates the heart's carotid baroreceptors, for treatment of adults with medically refractory heart failure involving a reduced-ejection-fraction of 35% or less who are not good candidates for other device therapies.  (Medscape)

Physicians Track Blood Flow to Brain Tumors During Noninvasive Stimulation

Aug. 15, 2019 - Scientists investigated blood flow to brain tumors during transcranial electrical stimulation, based on research that showed reduced blood flow to bodily tumors exposed to electric stimulation. (Science Daily)

Authors Analyze Methodology and Reporting of Placebo-Controlled Neuromodulation Trials

Aug. 7, 2019 - An article says placebo-controlled randomized clinical trials in neuromodulation are on the rise but a recently published meta-analysis points out important factors to report for clear interpretation of comparative results between study arms. (NeuroNews)

Study Examines Noninvasive Brain Stimulation and Appetite in Groups with Differing Dopamine Metabolism

Aug. 7, 2019 - A published study reports on an investigation of transcranial direct current stimulation to the brain's left dorsolateral prefrontal cortex in women with mild obesity. Effects on appetite were evaluated, as well as genetic differences in breakdown of dopamine. (EurekAlert)

Neurological Surgeons Hear About Deep Brain Stimulation for Chronic Pain

Aug. 6, 2019 - A presentation about deep brain stimulation (DBS) for chronic pain at the 2019 annual meeting of the American Association of Neurological Surgeons described the latest evidence and differences from DBS for movement disorder. (Pain Medicine News)

Research in Tehran Focuses on Brain Stimulation Devices for Cognitive or Medical Conditions

Aug. 5, 2019 - An article says that researchers working on cognitive and brain sciences in Iran plan to develop electrical brain stimulation devices to potentially treat several conditions. (Tehran Times)

Feature Discusses Research on Restoration of Movement Following Spinal Cord Injury

July 31, 2019 - A news feature describes research into using neurostimulation to restore some movement to people living with paraplegia after spinal cord injury. (Nature)

Article Covers Device Company's Plans to Address Memory Impairment

July 29, 2019 - A business news feature covers development of a brain stimulation device by Nia Therapeutics that is intended to treat memory impairment in patients with traumatic brain injury. (Technically Philly)

Journal's Annual Neuromodulation Research Prize Awards Work in Minimally Invasive Optical Brain Stimulation

Aug. 2, 2019 - The winner of the 2019 Science & PINS Prize for Neuromodulation describes preclinical work to stimulate neurons deep in the brain using optogenetics, tissue-penetrating near-infrared light, and nanoparticles injected into a target region. The particles convert the infrared light into visible light capable of causing membrane-bound rhodopsins to activate an ion channel. (Science)

Study Assesses Noninvasive Vagus Nerve Stimulation Impact on Autonomic Nervous System Balance

July 30, 2019 - Researchers interested in the effects of aging studied transcutaneous vagus nerve stimulation in healthy volunteers, including a cohort aged 55 and older, to study effects on vagal tone over a two-week period. (EurekAlert)

Literature Review Presents Periprocedural Needs of Patients with an Implanted Gastric Electrical Stimulator

July 29, 2019 - A review considers periprocedural needs of patients who have an implanted gastric electrical stimulation device. (Neuromodulation: Technology at the Neural Interface)

Brain Stimulation Research

July 29, 2019 - Researchers examined memory encoding beyond the hippocampal network and found a role for the posterior cingulate cortex upon stimulating the region during memory tests in volunteer epilepsy patients who were undergoing seizure monitoring. (Medical Xpress)

Results Published in Trial of Rechargeable Sacral Neuromodulation System

July 28, 2019 - Six-month results were published in the ARTISAN-SNM pivotal trial of a rechargeable sacral neuromodulation system in patients with urinary urge incontinence. (Uro Today)

Study Investigates Percutaneous Tibial Nerve Stimulation in Drug-Naive Patients with Overactive Bladder

July 28, 2019 - Results were presented at the 2019 American Urological Association meeting of percutaneous tibial nerve stimulation in drug-naive patients with overactive bladder who were prospectively followed over 12 weekly sessions in the RESET study. (Uro Today)

Researchers Pursue Biomimetic Feedback for Control of Prosthetic Hand

July 24, 2019 - With a participant using a bidirectional neuromyoelectric prosthetic hand, researchers tested dexterity after supplying a tactile precept through nerve stimulation designed to mimic natural sensory signals. (Science Robotics)

Company Closes $8 Million Funding Round

July 23, 2019 - Tivic Health Systems closed a funding round after raising $8 million in a series of seed-investment tranches. The company will use proceeds in launching its first product, which uses noninvasive electrical stimulation to relieve allergy-related sinus pain. (Yahoo Finance)

Article Mentions Trial of Deep Brain Stimulation in Stroke Recovery

July 21, 2019 - Six patients have received deep brain stimulation in a clinical trial of the intervention to aid physical recovery from stroke, and most have regained some movement, according to a news article. (Gulf News)

Researchers Publish Findings of Study of Anatomic Lead Placement in Spinal Cord Stimulation

July 19, 2019 - An Early View article reports on the DELIVERY study of anatomic lead placement without paresthesia mapping during the evaluation period of spinal cord stimulation for chronic pain. (Neuromodulation: Technology at the Neural Interface)

Case Report Published about a Woman with Refractory Anorexia who Received Deep Brain Stimulation

July 9, 2019 - In a woman with treatment-refractory anorexia nervosa, researchers report on testing of nutritional status, eating behavior, and body-image concern following deep brain stimulation that targeted the bed nucleus of the stria terminalis. (Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity)

Review Summarizes Evidence and Theory of Spinal Cord Stimulation in Chronic Pain

June 28, 2019 - A review summarizes current understanding of analgesia provided by spinal cord stimulation systems that produce paresthesias, or are paresthesia-free. (Bioelectronic Medicine)

Researchers Suggest a Modulation Effect on Seizure Network

April 15, 2019 - Researchers investigating the association of electrographic effects of responsive neurostimulation and seizure reduction in patients with epilepsy say the therapeutic outcomes appear to emerge from modulation of the seizure network over time. (JAMA Neurology)

Imaging Study Seeks Signatures of Pain Reduction in Parkinson's Disease Patients Receiving Neurostimulation

July 17, 2019 - Researchers studied brain responses through fMRI in Parkinson's disease patients for potential neural signatures of brain relief through deep brain stimulation (DBS). (Neurosurgery)

Researchers Look at Local Field Potential Activity in Patients Receiving Neurostimulation for Treatment-Resistant Depression

July 17, 2019 - A study of local field potential activity in the subcallosal cingulate region explores if it might be a candidate signal for monitoring deep brain stimulation for treatment-resistant depression, and a potential biomarker for development of adaptive treatment strategies. (Journal of Neurophysiology)

Authors Review Literature About Neurostimulation to Manage Chronic Pain

July 16, 2019 - A systematic review describes the state of the scientific literature for clinical effectiveness of neurostimulation to manage chronic pain. (Neuromodulation: Technology at the Neural Interface)

Researchers Look at Noninvasive Neurostimulation in Parkinson's Disease Patients with Depression

July 1, 2019 - A prospective pilot study explored repetitive transcranial magnetic stimulation to the dorsolateral prefrontal cortex in patients with Parkinson's disease and treatment-resistant depression. (Neurocase)

Study Examines Functional Connectivity in Patients with Depression Receiving Transcranial Magnetic Stimulation

June 21, 2019 - A preprint reports investigation into functional connectivity of brain regions involved in emotional regulation associated with a form of repetitive transcranial magnetic stimulation treatment in treatment-resistant major depressive disorder. The authors hypothesize about augmenting top-down regulation of emotion in this condition. (BioRxvi)

News Article Recaps Research Regarding Occipital Nerve Stimulation

July 16, 2019 - An article in Neuromodulation: Technology at the Neural Interface reports on burst occipital nerve stimulation in patients with chronic migraine and chronic cluster headache. (Neurology Advisor)

Neurostimulation Company Acquires Sensing-and-Stimulation Technology

July 16, 2019 - Nia Therapeutics, Inc. has acquired integrated circuit technology for brain sensing and stimulation developed by Cortera Neurotechnologies, Inc. Nia plans to use the technology as the core of its system for treating memory impairment. (Medium)

Review Covers Evidence and Future Design of Sham- and Placebo-Controlled Trials of Spinal Cord Stimulation

July 15, 2019 - An international team of authors reviewed randomized controlled trials of spinal cord stimulation (SCS) involving sham or placebo. They developed a checklist for the future design and reporting of SCS randomized controlled trials. (Neuromodulation: Technology at the Neural Interface)

Review: Neurorestorative Implants After Spinal Cord Surgery

July 11, 2019 - An article discusses the emerging role of implanted medical devices for improving functional recovery after spinal cord injury, such as research into brain-computer interfaces to augment physical rehabilitation. The article also notes that neuromodulation therapies that target the brain or spinal cord have helped improve motor and autonomic functions. (Bioelectronic Medicine)

Review Covers Intrathecal Drug Delivery Devices

July 15, 2019 - A review covers recent advances and future developments in intrathecal drug delivery for pain management. (Expert Opinion on Drug Delivery)

Headache Society Presentations Include Neurostimulation for Cluster Headache or Episodic Migraine

July 11, 2019 - An article about advancements in therapies being presented at the American Headache Society annual meeting mentions FDA approval of noninvasive vagus nerve stimulation in the past 12 months as an adjunct in prevention of cluster headache. The article also mentioned studies about a sphenopalatine ganglion microstimulator implant for terminating acute cluster attacks in patients with refractory chronic cluster headache. Data were presented at the meeting about noninvasive vagus nerve stimulation mechanisms and effectiveness in relief of episodic migraine. (Neurology Times)

CE Mark Granted for Migraine Relief Device

July 10, 2019 - Neurolief announced it received CE mark to market its noninvasive neurostimulation device for the relief of acute migraine as an over-the-counter device within the European Union. (Neuro News)

Article Surveys Current and Potential Treatments Involving Vagus Nerve Stimulation

July 10, 2019 - An article discusses advances in vagus nerve stimulation for migraine prevention and research into new potential applications, such as fighting lung infection in pre-term babies. (Leaps Magazine)

Young Child With Severe Dystonia Receives Deep Brain Stimulation Implant

July 10, 2019 - A 32-month-old girl with dystonia that interfered with eating and breathing has received deep brain stimulation in London. Doctors said previously the youngest child to receive the surgery was 3 years old. (The Guardian)

Developer of Cardiac Neuromodulation for Hypertension Closes Funding Round

July 10, 2019 - Orchestra BioMed completed a $34 million financing, which will help fund advancement of its implantable cardiac neuromodulation therapy for hypertension. (Globe Newswire)

Data Published from Clinical Trial of Neurostimulation for Central Sleep Apnea

July 10, 2019 - Respicardia, Inc. announced publication of 24- and 36-month data from a pivotal trial of its phrenic nerve stimulation in adults with moderate to severe central sleep apnea. This month, enrollment began in a study of the system in patients in Europe and the U.S. It will be a multi-center, prospective, open-label, single-arm study to collect safety and effectiveness data for up to five years. (Yahoo Finance)

Center Reports Retrospective Analysis of Spinal Cord Stimulator Explants

July 7, 2019 - Researchers at Harvard Medical School published a 15-year retrospective analysis of explantation of percutaneously placed spinal cord stimulator devices. (Pain Medicine)

Outcomes Reported in Study of Sub-Perception Spinal Cord Stimulation in Previously Implanted Subjects

July 2, 2019 - A journal article reports outcomes of the WHISPER randomized controlled trial, which evaluated sub-perception spinal cord stimulation in previously implanted subjects. (Neuromodulation: Technology at the Neural Interface)

Review: Neurostimulation Among Interventions in Upper-Limb Physical Rehabilitation After Stroke

July 2, 2019 - A review looks at published research about interventions for upper-limb motor rehabilitation after stroke, including brain stimulation and brain-computer interfaces. (Genetic Engineering & Biotechnology News)

Peripheral Nerve Stimulation Device Maker Featured in Regional Business Article

July 7, 2019 - A news article features SPR Therapeutics and its peripheral neurostimulation system, which applies stimulation about 1/2 inch from a peripheral nerve to treat pain in locations like the shoulder, back or knee. The article notes it can be used for phantom limb pain, among other types of pain. (Star Tribune)

Review Covers Noninvasive Stimulation in Substance-Use Disorders

July 2, 2019 – In a review article, an international group of co-authors summarizes the state of noninvasive brain stimulation applied in substance-use disorders. (Neuroscience & Biobehavioral Reviews)

Authors Focus on Transcranial Magnetic Stimulation for Depression and Physical Activity

July 2, 2019 - A paper reports on the link between people who respond to repetitive transcranial magnetic stimulation for depression and engagement in light physical activity. (Clinical Psychiatry News)

Study Explores Theta-Burst Transcranial Magnetic Stimulation in Post-Traumatic Stress Disorder

July 3, 2019 - An article covered new research into intermittent theta-burst transcranial magnetic stimulation in post-traumatic stress disorder. (Medscape)

Clinic to Offer Neurostimulation Therapy in Physicial Rehabilitation Program

July 3, 2019 - A clinic in Canada announced it will be offering a rehabilitation program to improve gait and balance deficits from mild to moderate traumatic brain injury, making use of a noninvasive neurostimulation device in addition to physical therapy. (Cision)

Study of Cardiac Neuromodulation for Hypertension Uses Varied Heart Pacing

June 4, 2019 - Orchestra BioMed Inc. announced presentation of two-year clinical data from its European study of cardiac neuromodulation for hypertension. The approach uses cardiac stimulation with a dual-chamber pacemaker and implantable pulse generator that varies atrioventricular delay in order to modulate baroreceptor activation. The study enrolled patients with medication-resistant hypertension who were also indicated for a pacemaker. The company said that in 2019 it plans to initiate a randomized, double-blind study of this BackBeat device. (Diagnostic and Interventional Cardiology)

Spinal Cord Stimulation Device Maker Raises Funds

June 28, 2019 - Saluda Medical completed a four-year term loan for an unspecified amount from Medtronic, and also raised $75 million in an equity round that was joined by Boston Scientific. The company said the transactions will help fund final development stages of its spinal cord stimulation system through global commercialization. (Mass Device)

Company Acquires Maker of Noninvasive Stimulation Treatment for Migraines

June 27, 2019 - DW Healthcare Partners has acquired Cefaly Technology, maker of noninvasive neurostimulation devices to treat migraine headaches. (Mass Device)

Foundation Funds Clinical Study of Neurostimulation in Rehabilitation from Spinal Cord Injury

June 26, 2019 - Helsinki University Hospital in Finland has received two years of funding from the Wings for Life Foundation to continue research into combining transcranial magnetic stimulation and peripheral nerve stimulation in a clinical study of rehabilitation in patients paralyzed by spinal cord injury. (Yahoo Finance)

Authors Suggest Factors Influencing Response to Neurostimulation Treatment Following Stroke

June 26, 2019 - A paper suggests two criteria that may help predict response after stroke to noninvasive brain stimulation. (EurekAlert)

Article Details Access to Deep Brain Stimulation for Parkinson's Disease Patients in Ireland

June 25, 2019 - A Parkinson's disease patient in Ireland points out that implantable pulse generators for deep brain stimulation are manufactured there, but patients eligible for the surgery must travel outside of Ireland to receive the treatment. (Waterford Live)

Article Documents Delivery of Neuromodulation Services for Epilepsy at a Southern U.S. Academic Center

June 25, 2019 - The University of Alabama at Birmingham has created an epilepsy neuromodulation clinic that provides vagus nerve stimulation or responsive neurostimulation services to patients from distances of up to 250 miles away, including three other states in the region. (Newswise)

Paper Presents Data on Urinary Function in Parkinson's Disease Patients Following Deep Brain Stimulation

June 25, 2019 - Co-authors in China published findings regarding the effects of deep brain stimulation on urinary function in more than 400 patients with Parkinson's disease. (Clinical Interventions in Aging)

Paper Reports on Study of Noninvasive Brain Stimulation for Migraineurs

June 25, 2019 - A study evaluated daily transcutaneous supraorbital nerve stimulation as a prophylaxis for chronic migraine. (Clinical Pain Advisor)

Study Looks at Factors Recorded on a Standard Clinical History and Change in Opioid Use After Neurostimulation for Chronic Pain

June 14, 2019 - In a chart analysis, a team of U.S. co-authors looked for factors that were statistically associated with cessation of chronic opioid use following successful spinal cord stimulation, such as the dosage used preoperatively. (Pain Practice)

PROMISE Trial Results Published

June 2019 - A prospective, open-label, parallel-group trial in Europe and the Americas, PROMISE, compared optimal medical management (OMM) alone vs. OMM plus multicolumn spinal cord stimulation in patients with predominant low back pain from failed back surgery syndrome. (Pain)

Canadian Provincial Advisory Body Seeks Public Input on Proposed Expansion of Frequencies in its Recommendation for Public Funding of Spinal Cord Stimulation for Chronic Pain

June 17, 2019 - The advisory body Health Quality Ontario, under the guidance of the Ontario Health Technology Advisory committee, seeks public input by July 8, 2019 on a proposed update of stimulation frequencies in its recommendation concerning public funding for spinal cord stimulation in adults with chronic non-cancer pain that is refractory to medical management. (Health Quality Ontario)

FDA Approves a Cochlear Implant Designed for MRI Compatibility

June 17, 2019 - The U.S. FDA has approved a new cochlear implant designed for compatibility with 1.5. and 3.0 Tesla MRI scans. The FDA also approved an integrated connectivity feature that allows streaming audio from compatible Android phones. (MD Magazine)

Researchers Study Vagus Nerve Stimulation in Rheumatoid Arthritis

June 14, 2019 - Data from a pilot study of vagus nerve stimulation in rheumatoid arthritis were presented at the annual European Congress of Rheumatology. (EurekAlert)

Company Seeks Full-Body MR-Conditional Approval for Its Neurostimulation System

June 12, 2019 - Nuvectra announced it is seeking full-body MR-conditional approval for its spinal cord stimulation system from the U.S. FDA. (Mass Device)

Researchers Publish Study of Peripheral Nerve Stimulation for Post-Amputation Pain

June 12, 2019 - A published study evaluated percutaneous peripheral nerve stimulation for chronic neuropathic pain after leg amputation. (Pain Medicine News)

FDA Issues De Novo Clearance for Neurostimulation Device for Pain Relief in Irritable Bowel Syndrome in Adolescents and Teens

June 7, 2019 - The FDA has cleared a percutaneous device worn behind the ear, that stimulates cranial nerves to relieve pain from irritable bowel syndrome in patients aged 11 - 18. (FDA)

News Coverage Features INS 14th World Congress and Innovations Day Preconference

June 2019 - An overview of the International Neuromodulation Society 14th World Congress recaps the presentations from the Innovations Day preconference, as well as from the opening plenary sessions and announcements made at the meeting. In addition, the publication publisher, James Cavuoto, spoke with INS 2019 meeting chair Marc Russo, MBBS DA(UK)FANZCA, FFPMFANZCA, about what makes Australia special in this space (video). Cavuoto has posted a recording of his 30-minute Innovations Day talk on "Tips and Tricks in Determining Newsworthiness of Innovations". (Neurotech Reports)

Couple Donate $1 Million to Fund Studies of Neurostimulation in Spinal Cord Injury Patients

June 6, 2019- A former motor-vehicle accident rehabilitation patient and his wife have donated $1 million to launch the Kessler Foundation Center for Spinal Stimulation in New Jersey. The donation will fund three rehabilitation studies of epidural and transcutaneous spinal cord stimulation in people with chronic spinal cord injury. (EurekAlert)

Noninvasive Brain Stimulation Studied in Obsessive Compulsive Disorder

June 6, 2019 - An article summarizes a published study of deep transcranial magnetic stimulation in obsessive compulsive disorder. (Healio)

Company Launches Wearable Brain Stimulation Device in the U.K.

June 4, 2019 - In the U.K., Flow Neuroscience has launched a wearable headset for depressed adults that delivers low levels of brain stimulation to the left frontal lobe, and is accompanied by a behavioral therapy app. (Fierce Biotech)

Paper Evaluates Fully Implanted Wireless Spinal Cord Stimulation Devices During a 30-Day Screening Trial

June 3, 2019 - A journal article presents and discusses effects and complications seen in a 30-day trail of a wireless percutaneous spinal cord stimulation system. (Neuromodulation: Technology at the Neural Interface)

Company Reports an Additional $17.7 Million Raised in Funding Round

June 3, 2019 - CVRx, a neuromodulation device company targeting heart failure, reported raising an additional $17.7 million in a recently completed funding round, in which it raised approximately $75.4 million. (Mass Device)

Closed-Loop Spinal Cord Stimulation Data Presented

June 3, 2019 - Saluda Medical Pty Limited announced presentations of data from two clinical studies of its closed-loop spinal cord stimulation system for pain. (PR Newswire)

Review: The Dorsal Root Ganglion as a Unique Target for Neuromodulation

June 1, 2019 - A review article describes the dorsal root ganglion as a target for neuromodulation for pain. (Pain Medicine)

News Segment Focuses on Participant of Closed-Loop Spinal Cord Stimulation Clinical Trial

May 31, 2019 - A Sydney news channel featured a patient who was involved in the Evoke clinical trial of a closed-loop spinal cord stimulator, and included comments from researchers. (9 News)

FDA Clears Noninvasive Device for Acute Migraine

May 28, 2019 - A noninvasive peripheral nerve stimulator received de novo FDA clearance for acute treatment of migraine headache. The device by Theranica Bioelectronics is a wireless patch worn on the arm. (Medtech Dive)

Results Reported from Clinical Trial of Neurostimulation in Ischemic Stroke

May 28, 2019 - Findings from a clinical trial of sphenopalatine ganglion stimulation in acute ischemic stroke were presented at the European Stoke Organization Conference. The findings were simultaneously published in The Lancet. May 24, 2019 (Healio)

Article Features Use of Deep Transcranial Magnetic Stimulation for Depression

May 27, 2019 - An article profiles a young woman with depression who uses deep transcranial magnetic stimulation for depression. (Inside Edition)

Spinal Cord Stimulation Presentations in Sydney Listed

May 26, 2019 - Nevro Corp. announced a series of data presentations in Sydney concerning its nerve stimulation therapy for chronic pain. (Chestnut Post)

Sydney-Area Pain Patient Discusses Use of Neuromodulation

May 25, 2019 - A news feature profiles an ex-Army infantryman in Australia who for the past three years has used spinal cord stimulation to manage chronic pain symptoms from a back injury in the 1980s. In the coverage, International Neuromodulation Society (INS) 14th World Congress chair Dr. Marc Russo comments about the therapy. In addition, INS 14th World Congress Public Event chair Dr. Nick Christelis was interviewed on an afternoon ABC radio program in Melbourne May 24 about neuromodulation therapy and pain treatment, as well as in an article in the Melbourne-area Herald Sun. (ABC Radio)

Government Agency Announces Funding for Noninvasive Brain-Machine Interface Projects

May 21, 2019 - Six research programs have received funding in the latest round of DARPA grants under its Next-Generation Nonsurgical Neurotechnology (N3) program, which is designed to support research into high-resolution, bidirectional brain-machine interfaces intended to allow service members or mission commanders to function in dynamic machine-influenced operations that unfold at rapid speed. (Phys.org)

Noninvasive Neurostimulation Company Receives $50 Million Funding Round

May 21, 2019 - Cala Health has raised $50 million in private funding before the launch of its weaable neurostimulation device to address hand tremor in essential tremor patients. (MedCity News)

Data from Closed-Loop Spinal Cord Stimulation Studies to be Presented at INS 14th World Congress in Sydney

May 20, 2019 - Saluda Medial announced new data from multiple studies evaluating the company's closed-loop spinal cord stimulation system will be presented in plenary lectures and oral abstracts during the International Neuromodulation Society 14th World Congress. Also, Saluda CEO John Parker will speak at the pre-congress Innovations in Neuromodulation event, "Disruptive Innovation: The Driving Force of Progress in Neuromodulation". (PR Newswire)

Noninvasive Stimulation Under Study for Migraine Treatment

May 20, 2019 - Theranica Bio-Electronics is pursuing development of a stimulator worn on the upper arm to potentially provide acute migraine treatment. (ISRAEL21c)

Startup Pursuing Neurostimulation for Opioid Withdrawal Wins Technology Competition

May 20, 2019 - Spark Biomedical received $50,000 as first-place winner in the Texas A&M New Ventures Competition for its work to develop a noninvasive neurostimulation treatment for opioid withdrawal and addiction. (My San Antonio)

Meeting Presentation Concerns Vagus Nerve Stimulation in Crohn's Disease

May 20, 2019 - SetPoint Medical announced presentation of a European study of its implanted vagus nerve stimulator in patients with Crohn's Disease. (Globe Newswire)

Collaboration Pursues Closed-Loop Brain Stimulation Approach

May 17, 2019 - At a progress report about DARPA-funded neuroscience technologies, researchers discussed their work to analyze and potentially influence mood-related brain activity, with an ultimate goal of developing a closed-loop neurostimulation system. (IEEE Spectrum)

Study Investigates Deep Brain Stimulation to the Ventral Tegmental Area in Chronic Cluster Headache

May 16, 2019 - An article reports on a study of deep brain stimulation to the ventral tegmental area in patients with refractory chronic cluster headache. (Clinical Pain Advisor)

Visual Prosthesis Company Announces Plans

May 16, 2019 - Second Sight Medical plans to accelerate development of its Orion visual cortical prosthesis system to address various types of vision loss. (Mass Device)

Release Describes Chronic Pain Patient's Journey and the Role of Neuromodulation Therapy

May 15, 2019 - A preconference of the International Neuromodulation Society 14th World Congress will include presentations from experts and patients on neuromodulation for chronic pain, bladder conditions, and movement disorder. A news release previews the story of a chronic pain patient who will speak, and provides background information about neuromodulation therapy and neurostimulation for chronic pain in Australia. (Scimex)

Review: Current Perspectives on Deep Brain Stimulation in Obsessive Compulsive Disorder

May 15, 2019 - A review considers current perspectives on deep brain stimulation in the treatment of obsessive compulsive disorder. (Neuropsychiatric Disease and Treatment)

Company Partners with U.S. National Institutes of Health Neuroscience Initiative

May 14, 2019 - Abbott announced it is partnering with the U.S. BRAIN Initiative by providing its neuromodulation technologies for research related to chronic pain and movement disorder. (Medtech Dive)

Study Examines Influence of Weight on Pain Relief from Spinal Cord Stimulation

May 14, 2019 - A study reports spinal cord stimulation outcomes in the context of patients' body-mass index. (Pain Medicine News)

New TMS Approach Offered in North Carolina for Obsessive Compulsive Disorder

May 14, 2019 - A North Carolina private medical practice will offer deep transcranial magnetic stimulation (TMS) for obsessive compulsive disorder. (WRAL TechWire)

Company's Peripheral Nerve Stimulator Implanted in Australia

May 13, 2019 - Bioness, Inc. announced its first successful implantation of its peripheral nerve stimulator in a pain patient in Australia. (P&T Community)

Data Presented from Heart Failure Clinical Trial

May 10, 2019 - Results of the final design of the BeAT-HF trial, a device-based neuromodulation trial in heart failure patients with reduced ejection fraction, were presented at the Heart Rhythm Society Annual Scientific Sessions. The device in the pivotal trial uses carotid baroreceptor stimulation. (Healio)

Researchers Investigate Noninvasive Neurostimulation for Bladder Function After Spinal Injury

May 9, 2019 - A study was presented that looked at change in measured lower urinary tract function in spinal injury patients who tried transcutaneous spinal cord stimulation. (Uro Today)

Article Recounts Companies' Exploration of Devices to Address Hypertension

May 4, 2019 - A business-news feature about Minnesota companies that are are looking into a potential market for devices to address hypertension mentions neuromodulation device maker CVRx, which sells a device for hypertension in Europe and is testing a device for heart failure treatment in the U.S. (Star Tribune)

Clinical Study of Noninvasive Neurostimulation Reported in Acute Migraine

May 9, 2019 - A journal article reports results of a noninvasive neurostimulation method in acute migraine. In the randomized, double-blind, placebo-controlled clinical trial, remote electrical neuromodulation was intended to "induce conditioned pain modulation – an endogenous analgesic mechanism in which conditioning stimulation inhibits pain in remote body regions". (Headache: The Journal of Head and Face Pain)

Auricular Nerve Stimulation Studied in Atrial Fibrillation

May 9, 2019 - Researchers from the TREAT-AF study reported on vagus nerve stimulation and atrial fibrillation at the Heart Rhythm Society Scientific Sessions. The study concerned daily noninvasive stimulation at home, after training, using low-level transcutaneous electrical stimulation of the vagus nerve auricular branch, by clip at the opening of the ear, attached to the tragus. (Healio)

Profile Describes Patient's Progress After Stroke with Paired Vagus Nerve Stimulation

May 8, 2019 - A stroke patient is profiled whose hand function improved after participation in a clinical trial that pairs vagus nerve stimulation with physical rehabilitation. (BBC News)

Neural Interface Electrode Clinical Trial Enrollment Begins

May 7, 2019 - WISE Srl  announces enrollment of the first patient in the WIN study (WISE Cortical Strip for Intraoperative Neurophysiological Monitoring). The study is enrolling patients at four centers in Germany and Switzerland who are undergoing intraoperative monitoring for brain tumor or epilepsy surgeries. (BC3 Newswire)

Feature Article Describes Study of Neurostimulation for Addiction

May 8, 2019 - An article features a participant in a research study in China of deep brain stimulation for addiction. (Associated Press)

Newspaper in the United Kingdom Covers U.S. Teen's Neurostimulation Treatment for Tourette Syndrome

May 7, 2019 - A young man in Iowa received deep brain stimulation for his severe case of Tourette Syndrome. (Daily Mail)

Results Released from Clinical Trial of Sacral Neuromodulation

May 6, 2019 - Axonics Modulation Technologies released results of its clinical trial of sacral neuromodulation for urinary dysfunction. (Mass Device)

Sydney Area Patient Plans to Present His Experience of Deep Brain Stimulation for Parkinson's Disease

May 3, 2019 - A Parkinson's disease patient in the suburbs of Sydney told his local newspaper why he will be presenting about his deep brain stimulation treatment at a public event by the International Neuromodulation Society and the Neuromodulation Society of Australia and New Zealand on May 26 prior to the INS 14th World Congress in Sydney. He described his journey as going from one small shuffle to many great leaps. (St. George Leader)

Pain Patients Studied With More Than One Mode of Spinal Cord Stimulation

May 2, 2019 - An article discusses pain patients who were switched from one mode of spinal cord stimulation to another. (NeuroNews)

Review: Novel Spinal Cord Stimulation Modes Compared to Traditional

May 2, 2019 - An article summarizes a review from Current Pain and Headache Reports that compared traditional and novel forms of spinal cord stimulation. (Clinical Pain Advisor)

Authors Publish Meta-Analysis of Medication Reduction in Spinal Cord Stimulation Patients

April 30, 2019 - A review of comparative studies of spinal cord stimulation in chronic back and/or limb pain synthesized evidence regarding opioid and pain medication reduction. (Journal of Pain Research)

TV Station Features Amputee Treated with Neurostimulation

April 29, 2019 - In a local news segment, an amputee describes his experience using dorsal root ganglion stimulation for phantom limb pain. (9and10news.com)

Pain Medicine Talk Presents the Art of Neuromodulation

April 29, 2019 - A talk at the Faculty of Pain Medicine of the Australian and New Zealand College of Anaesthetists (ANZCA) Annual Pain Medicine Symposium presented a view about the "art" of delivering neuromodulation therapy. The topic was covered in a related article by a New Zealand news site, Stuff. (Scoop)

Article Features Parkinson's Disease Patient Enrolled in Clinical Trial of Spinal Cord Stimulation to Improve Gait

April 26, 2019 - A news feature centers on a woman who participated in a clinical trial of spinal cord stimulation, an investigational approach intended to improve freezing of gait in Parkinson's disease. (National Post)

Military Publication Describes Interest in Wearable Devices to Enhance Mental Acuity

April 25, 2019 - A news feature describes the U.S. military's interest in wearable neurostimulation devices that might enhance soldiers' mental alertness. (Military.com)

Television Segment Features Man After His Deep Brain Stimulation for Dystonia from Tourette Syndrome

April 26, 2019 - A man with Tourette syndrome received deep brain stimulation to lessen his disabling dystonia. (WTIC)

International Neuromodulation Society Issues News Release About Its 14th World Congress

April 23, 2019 - The International Neuromodulation Society will present plenary lectures, and nearly 400 abstracts, by researchers from 22 countries during the INS 14th World Congress in Sydney May 25 - 30, 2019, “Neuromodulation: Leading a Global Medical Revolution.” (NeuroNews)

National Health Service Will Provide Auditory Brainstem Implants to Pediatric Patients at Two Centers

April 23, 2019 - The National Health Service in England will make auditory brainstem implants available to profoundly deaf children aged 5 and under who are unable to use hearing aids or cochler implants due to missing or damaged cochlea or auditory nerves. (PharmaTimes)

Data Presented from Trial of Closed-Loop Spinal Cord Stimulation

April 24, 2019 - Phase 2 results of the EVOKE study were presented at the annual scientific meeting of the American Association of Neurological Surgeons. The randomized, double-blinded study compared spinal cord stimulation for pain delivered with, and without, adjustment of simulation depending on electrophysiologic response of multiple nerve fibers -- evoked compound action potentials. (Medscape)

Proof-of-Principle Study Concerns Research Into Prosthetic Voice Development

April 24, 2019 - In epilepsy patients undergoing brain monitoring, researchers studied turning brain signals generated when they silently imagined articulating something into an artificial voice. (New York Times)

FDA Approves a Noninvasive Neurostimulation Device for Attention-Deficit Hyperactivity Disorder

April 20, 2019 - The U.S. FDA has approved a external trigeminal nerve stimulation system to treat ADHD i children aged 7 - 12 who are not taking medication for the disorder. (USA Today)

Analysis Suggests Plasticity May Play a Role in Effect of Responsive Neurostimulation in Epilepsy

April 19, 2019 - An analysis of seizure patterns in patients implanted with a responsive neurostimulation system for epilepsy suggests the therapy exerts its effects by remodulating neural networks. (Medscape)

Company Starts Clinical Trial of a Wearable Device for Overactive Bladder in Women

April 19, 2019 - FemPulse has launched a clinical trial to enroll 21 women at three U.S. cites in a trial of the company's intravaginal neuromodulation device intended to address overactive bladder. (MD+DI)

Paper Presents Two Decades of Device and Therapy Survival Data

April 2019 - Researchers analyzed device and therapy survival data at one institution from 1994 - 2015 for three neuromodulation therapies" deep brain stimulation, vagus nerve stimulation, and spinal cord stimulation. (Journal of Neurosurgery)

Australia Team Studies Noninvasive Brain Stimulation in Depression

April 18, 2019 - A team in Australia has published an early investigation into home-administered transcranial direct current stimulation for depression. (ABC News)

Collaborators Research Noninvasive Nerve Stimulation in Rheumatoid Arthritis

April 17, 2019 - Collaborators published some early findings about noninvasive nerve stimulation of patients with rheumatoid arthritis. The research team measured production of circulating inflammatory agents. (Medical Express)

Parkinson's Disease Patients in Ireland Seek Increased Services

April 17, 2019 - A patient in Ireland with Parkinson's disease demonstrated on live television turning off, temporarily, his deep brain stimulation device, in order to draw attention to requests for more nearby services for patients with Parkinson's disease. (Irishcentral.com)

Targeted Drug Delivery and Healthcare Utilization Studied in Cancer-Related Pain

April 9, 2019 - A study has explored the association between targeted drug delivery and health-care utilization costs in cancer-related pain. (Oncozine)

Company Raises $28 Million as It Plans an Initial Public Offering

April 16, 2019 - Brainsway, a transcranial magnetic stimulation device company,  raised $28 million in an offering and plans to list on the Nasdaq at $11 a share. (Renaissance Capital)

Patient with Functional Deficits after Traumatic Brain Injury is Participating in a Study of Deep Brain Stimulation

April 13, 2019 - During an informal public brain-science convention, a case was mentioned in which a woman with a past traumatic brain injury has received deep brain stimulation to an area of the thalamus involved in activation of the frontal cortex and the basal ganglia. (New York Times)

The International Neuromodulation Society and the Neuromodulation Society of Australia and New Zealand will Present a Free Public Event in Sydney on Neurostimulation Therapies

April 11, 2019 - The International Neuromodulation Society and Neuromodulation Society of Australia and New Zealand are presenting a free public event , open to the public, about neurostimulation for chronic conditions such as chronic pain, overactive bladder, and Parkinson's disease. INS and chapter leaders will join national experts from Australia in presenting the therapies and the context of the opioid crisis. Three Australian patients will also describe their experiences with the therapies. (News-Medical.net)

News Profile Features the First Patient in Alabama to Receive Deep Brain Stimulation for Epilepsy

April 11, 2019 - In a profile, a young man who became the first person in his state to receive deep brain stimulation for epilepsy is interviewed, and his treatment team describes the procedure and the therapy. (UAB News)

Sacral Neuromodulation for Fecal Incontinence Covered in TV Segment

April 11, 2019 - A television piece covered the emergence of sacral nerve stimulation for fecal incontinence. (CBS 6 TV)

Company Announces FDA Response to De Novo Device Application

April 10, 2019 - Helius Medical Technologies announced the FDA declined its request for de novo classification and 510(k) clearance of its portable neuromodulation stimulator (PoNS) device that is intended to augment physical rehabilitation; the company said the FDA indicated it could generate more data and resubmit the application. (First Word Medtech)

Radio Interview: Woman Describes Participation in a Brain Stimulation Trial

March 29, 2019 - In an hour-long radio program, a woman who participated in a clinical trial of deep brain stimulation for obsessive compulsive disorder described her reliance on, and appreciation for, the intervention over the last six years, although she has needed increased levels of stimulation over time. (Invisibilia/NPR)

Authors: Bi-directional Brain Stimulation Electrodes May Expand Therapeutic Options

April 8, 2019 - A paper in Nature Reviews Neurology suggests that bi-directional electrodes that can stimulate brain targets and record activity could be applied to conditions beyond Parkinson's disease, such as depression, Tourette syndrome, and obsessive compulsive disorder. (Science Daily)

Research Explores Noninvasive Brain Stimulation for Improving Working Memory

April 8, 2019 - A study in Nature Neuroscience explored using high-density transcranial alternating current stimulation in older adults to influence brain rhythms and working memory. The double-blind study looked at different stimulation schemes and sham stimulation in older adults and younger adults who were given working-memory tasks while their brainwave rhythms were tracked. (NPR)

Publication Reports on Peripheral Nerve Stimulation in Post-Amputation Pain

April 8, 2019 - SPR Therapeutics announced publication of a study in the journal Regional Anesthesia and Pain Medicine about use of peripheral nerve stimulation for residual limb pain and phantom limb pain. (Globe Newswire)

Clinical Trial to Start on Brain-Computer Interface for Communication by Paralyzed People

April 7, 2019 - An article describes a research project to implant a brain electrode without open surgery to potentially enable the paralyzed clinical trial participants to generate text using their thoughts in order to communicate. (Futurism)

Journal Article Looks at Comparative Costs of Targeted Drug Delivery for Pain in Cancer Patients

April 5, 2019 - A group of co-authors conducted a retrospective economic evaluation comparing conventional medical management alone vs. targeted drug delivery and conventional medical management for pain relief in patients with cancer. (JAMA Network Open)

Portuguese News Article Describes Deep Brain Stimulation

April 4, 2019 - An article describes the extent of deep brain stimulation for Parkinson's disease in Portugal. (The Portugal News)

Research Team Investigates Potential to Restore the Sense of Smell through a Stimulation Implant

April 2019 - A research team is investigating creation of an implant to restore a sense of smell to people who have lost it due to irrecoverable neural damage. The envisioned implant would stimulate the brain's olfactory bulb. (Scientific American)

News Feature Profiles Famed Race Car Driver Who Is Receiving Deep Brain Stimulation for Parkinson's Disease

April 4, 2019 - A Daytona 500-winning race-car driver is undergoing deep brain stimulation for Parkinson's disease. (The Tennessean)

Research Explores Brain Rhythms and Cognition in Some Types of Deep Brain Stimulation

April 4, 2019 - Researchers are studying patients who have deep brain stimulation targeting the ventral internal capsule and ventral striatum to learn if the stimulation aids cognitive control of atypical emotions. They examined the power of a specific low-frequency brain rhythm in the prefrontal cortex. (Technology Networks)

Analysis Explores Control of Essential Tremor with Deep Brain Stimulation Over Time

April 4, 2019 - A follow-up analysis of 20 patients who underwent deep brain stimulation for essential tremor more than 10 years ago looked at durability of the therapy. Experts commented about age at implant, disease progression, and the possibility of habituation. (Neurology Today)

Initial Data from Post-Market Study of Directional Deep Brain Stimulation Presented at Meeting

March 29, 2019 - Initial data were released in a post-market study of directional deep brain stimulation in Parkinson's disease. The data were reported at the third international Brain Stimulation Conference in Vancouver, B.C., Canada. (NeuroNews International)

Paper Reports Seven-Month Results from Study of Wireless Neurostimulator for Pain at Two Frequencies

March 25, 2019 - A randomized controlled study evaluated a wireless spinal cord stimulator at two different simulation frequencies for the treatment of chronic pain from failed back surgery syndrome. (Pain Medicine)

Review Assesses Published Clinical Trials of Noninvasive Brain Stimulation in Acute Depressive Episodes

March 28, 2019 - The BMJ has published a systematic review and meta-analysis of clinical trials of several types of noninvasive brain stimulation from 2009 - 2018 for acute treatment of major depressive episodes in adults. The lead author provided comment about treatment effectiveness compared to sham. (UPI / HealthDay News)

European Patent Allowance Covers Prediction of Responders to Transcranial Magnetic Stimulation for Depression

March 28, 2019 - Mynd Analytics, Inc. announced a European patent allowance on its process and outcome data for predicting non-response of patients to transcranial magnetic stimulation for depression. The approach involves use of individualized Quantitative EEG (QEEG) features. (Globe Newswire)

Japanese Company Pursues Several Applications of Wearable Neurostimulation Devices

March 27, 2019 - The Japanese company WAT Medical is pursuing wearable stimulators to address issues such as nausea, headache, and potentially what they term as "vision weakness" as well as night-time alertness. (Cision)

Company Announces FDA Approval of a Noninvasive Brain Stimulation Device

March 27, 2019 - The company Innovative Neurological Devices announced FDA approval of its wearable cranial electrotherapy stimulator for treatment of anxiety, depression and insomnia. (Medscape)

Clinical Trial of Vagus Nerve Stimulation in Treatment-Resistant Depression Will Include a Sham Arm

March 27, 2019 - A clinical trial of vagus nerve stimulation in treatment-resistant depression will now include a sham arm, according to a description on Clinicaltrials.gov. (Mass Device)

Pilot Study Assessed Trigeminal Nerve Stimulation in Children with ADHD

March 26, 2019 - A blinded sham-controlled pilot study investigated trigeminal nerve stimulation in children with ADHD. The study also evaluated corresponding brain activation as seen in resting-state quantitative EEG. (Healio)

Partnership Created to Develop Potential Noninvasive Neurostimulation Treatment for Spasticity

March 26, 2019 - WeHealth and PathMaker Neurosystems have formed a partnership to develop a noninvasive stimulation system to treat spasticity by simultaneously targeting associated spinal and peripheral sites for the targeted muscle. (MDDI)

Engineers Receive a $1.8 Million Grant to Research Brain Implant Biocompatibility

March 27, 2019 - Researchers have received a $1.8 million grant to study ways to minimize tissue reaction to brain implants that may degrade their long-term effectiveness. (MSU Today)

FDA Clearance Announced for Theta Burst Transcranial Magnetic Stimulation Protocol for Patients with Depression

March 25, 2019 - Nexstim Plc announced it has received FDA clearance for a protocol that calls for sessions of theta burst transcranial magnetic stimulation to last three minutes in patients with major depressive disorder. (Nasdaq)

Multi-Institution, $9.7 Million, BRAIN Initiative Grant Will Support Research into Auditory Nerve Stimulation

March 22, 2019 - The National Institutes of Health has given a five-year, $9.7 million grant through its BRAIN Initiative to a global team of collaborators, led by the University of Minnesota, to investigate addressing hearing loss by directly stimulating the auditory nerve. (Idaho State Journal)

Presentations Cover Differential Stimulation of Glial Cells

March 22, 2019 - Abstracts presented at the 2019 meeting of the North American Neuromodulation Society covered an investigation into the pain relief provided by continuous differential-target multiplexed spinal cord stimulation (SCS). A basic science abstract reported effects of this approach on mechanical and thermal pain in mice. A second abstract reported on the impact of differentially targeting glia (astrocytes, microglia, oligodendrocytes) and neurones in a SCS crossover study in low-back pain. (NeuroNews)

In Roundtable, Pain-Management Experts Share Best Practices and Current Questions in Neuromodulation

March 2019 - An article summarizes observations and experiences shared in a roundtable discussion on current best practices and key questions in neuromodulation. The discussion took place during the 2019 meeting of the American Academy of Pain Medicine. (Practical Pain Management)

Unanticipated Response Noted in Cingulum Stimulation During Pre-Surgical Epilepsy Brain Mapping

March 21, 2019 - A clinician reports affective response in three epilepsy patients from brain stimulation to the dorsal anterior segment of the cingulum bundle, which was carried out during pre-surgical mapping. He purports the finding may have potential implications for surgery. (Neurology Today)

Chronic Pain Neurostimulator Available in Canada

March 21, 2019 - An article announces the availability of a wireless spinal cord stimulator in Canada for chronic pain. (Daily American)

Article Covers Several Bioelectronic Therapy Developments

March 20, 2019 - An article about electroceuticals summarizes developments at six neuromodulation companies that have developed devices for a range of conditions. (Nanalyze)

Article Summarizes Deep Brain Stimulation Findings in Several Conditions Other Than Movement Disorders

March 12, 2019 - Recent findings are summarized in brain-stimulation implants in epilepsy, treatment-resistant depression, and Alzheimer's disease. Deep brain stimulation history and neuronal and vascular effects are also discussed. (PNAS)

Device Maker Partners with a U.S. Insurance-Claims-Processing Medical Equipment Distributor

March 20, 2019 - Endonovo Therapeutics, Inc., which markets a noninvasive stimulator for treatment of soft tissue injury and chronic wounds, announced a partnership with a provider of Medicare and Medicaid claims service and equipment, SunMED Medical Solutions. (Nasdaq)

Review Summarizes Approaches to Transcranial Magnetic Stimulation Treatment in Trauma-Related Conditions

March 19, 2019 - A review looks at repetitive transcranial magentic stimulation in trauma-related conditions, and treatment frequencies and stimulation targets used in the presence of post-traumatic stress disorder. (Neuropsychiatric Disease and Treatment)

Company Seeks FDA Approval for Use of Its Noninvasive Brain Stimulation in Alzheimer's Disease

March 19, 2019 - An FDA advisory panel will be discussing an application for Neuronix's NeuroAD machine, which provides transcranial magnetic stimulation, to be approved for use in slowing development of Alzheimer's symptoms when used in conjunction with cognitive training. (IEEE Spectrum)

Researchers Examine Changes in Quality of Life for Parkinson's Disease Patients After Deep Brain Stimulation

March 19, 2019 - A study in Neurology examined the changes in quality of life of Parkinson's disease patients who participated in a deep brain stimulation study for patients younger than 61, finding a difference in improvement depending on the baseline level. (Parkinson's News Today)

Researchers In Germany Report on Deep Brain Stimulation in Major Depression

March 19, 2019 - An article in Neuropsychopharmacology reports on deep brain stimulation to part of the brain's reward system, the superoloateral medial forebrain bundle, in major depression. (EurekAlert)

CE Mark Announced for Neurostimulator to Treat Obstructive Sleep Apnea

March 18, 2019 - The company Nyxoah announced its neurostimulator for obstructive sleep apnea was approved for marketing in Europe. (Medgadget)

Deep Brain Stimulation Implantation Performed Remotely Over 5G Mobile Network in China

March 18, 2019 - A surgeon in China used a 5G mobile network to guide remote-control robots for implantation of deep brain stimulation leads in a Parkinson's disease patient 1,800 miles away in Beijing. (Daily Mail)

Maker of Stimulation Device for Acute Migraine Raises $35 Million in Series B Funding

March 18, 2019 - The Israeli company Theranica announced it has raised $35 million in a Series B round of funding. The company is making a wearable stimulation device for acute migraine. (PE Hub Network)

Data Presented in Small Case Series about Effect of Intranasal Stimulator on Ocular Pain

March 18, 2019 - An abstract presented at the 2018 World Congress on Pain concerned a small case series in which patients with persistent post-herpetic eye pain received a dose of intranasal stimulation during an office visit, to investigate observations made in patients who used the device for dry eye and noticed an impact on their corneal pain. (Pain Medicine News)

Noninvasive or Minimally Invasive Technology is Intended to Target Chronic Pain

March 16, 2019 - An article describes a mask that delivers sound and light stimuli based on heart rate to potentially address some chronic pain; the article mentions other noninvasive or subcutaneous devices that provide stimulation to treat different types of pain. (CNBC)

Presentations Concern Vagus Nerve Stimulation in Heart Failure

March 15, 2019 - LivNova PLC announced that three abstracts about the use of implantable neuromodulation technology for chronic heart failure would be presented at the 68th Annual Scientific Session of the American College of Cardiology in New Orleans, March 16-18, 2019. The company's vagus nerve stimulation system to deliver autonomic regulation therapy, Vitaria, is undergoing a prospective, international, randomized, controlled clinical trial (ANTHEM-HFrEF Pivotal Study). (Finger Lakes Times)

Clinical Trial Will Evaluate Deep Brain Stimulation in Early Parkinson's Disease

March 15, 2019 - A phase three clinical trial of deep brain stimulation in early Parkinson's disease is being led by Vanderbilt University. (KSAT)

Company Licenses Noninvasive Vagus Nerve Stimulation Technology

March 12, 2019 - Cala Health, Inc. has licensed noninvasive technology developed from research on transcutaneous vagus nerve stimulation and respiratory-gated vagal afferent nerve stimulation, for its portfolio of wearable therapies for chronic disease. The Massachusetts General Hospital developers of the technology will serve as scientific advisors to the company. (AP News)

Clinical Trial Evaluated Noninvasive Nerve Stimulation in Children with ADHD

March 12, 2019 - A randomized, double-blind trial evaluated trigeminal nerve stimulation in children with attention deficit hyperactivity disorder (ADHD). (Medical Xpress)

Review Covers Therapeutic Developments in Transcranial Magnetic Stimulation

March 12, 2019 - A review article covers recent evidence of advancements in transcranial magnetic stimulation in a range of clinical applications. (MDedge)

Study Tests Noninvasive Brain Stimulation in Worriers

March 7, 2019 - Researchers tested transcutaneous vagus nerve stimulation in chronic worriers, measuring intrusions of negative thought, and worry induction. (University of Leiden)

Journal Reports Data from Comparative Study of Deep Brain Stimulation Targets in Obsessive Compulsive Disorder

March 7, 2019 - A new study in Biological Psychiatry compared which distinct symptoms were improved in obsessive compulsive disorder through deep brain stimulation of two different brain targets. (Science Daily)

Neurosurgeon Discusses Neuromodulation for Epilepsy

March 7, 2019 - An interview presents neuromodulation treatments for epilepsy, including deep brain stimulation. (Neurology Times)

Review Looks at Emergence of Epidural Spinal Cord Stimulation after Spinal Cord Injury

March 6, 2019 - A review article summarizes epidural spinal cord stimulation to facilitate the function of the sensorimotor network after spinal cord injury. (Neuromodulation: Technology at the Neural Interface)

Researchers in Spain Investigate Noninvasive Brain Stimulation and Self-Reported Aggressiveness

March 6, 2019 - Researchers in Spain are testing the effect of transcranial direct current stimulation on aggressive urges, following publication of data in Neuroscience in January. (Futurism)

Neuromodulation Company Announces First Commercial Use of Its Noninvasive Device

March 5, 2019 - Helius Medical Technologies, Inc. announced the first commercial use of its portable neuromodulation stimulator in patients in Canada with balance issues due to mild to moderate traumatic brain injury. (Nasdaq)

Study Follows Pain Patients for 18 Months After Neurostimulator Implant

March 2, 2019 - An article describes a study in which pain patients were followed for 18 months after receiving dorsal root ganglion stimulation. (Health24)

Comparative Study Looks at Impulsiveness in Parkinson's Disease Patients

March 1, 2019 - A journal article summarizes an investigation that compared impulsiveness in Parkinson's disease patients, who were treated with deep brain stimulation of the subthalamic nucleus, with two other groups - healthy control subjects, and Parkinson's patients who only received medication. (Parkinson's News Today)

Researcher Discusses Neurostimulation for Pain

Feb. 26, 2019 - A journal editor speaks about research into high frequency stimulation for pain. (Pain Medicine News)

Presentation Covers Three-Year Follow-Up Results of Neurostimulator in Overactive Bladder

March 2, 2019 - At the Winter 2019 meeting of the Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction, an author presented three-year follow-up results of a prospective multi-center study of a wireless implantable tibial nerve stimulator in patients with overactive bladder. (UroToday)

Psychiatry Journal Publishes Recent Developments in Transcranial Magnetic Stimulation

March 2019 - An overview of transcranial magnetic stimulation in Current Psychiatry summarizes recent developments in the therapy. (MDedge)

Pain Fellows Invited to Enroll in a Neuromodulation Video Curriculum to Begin in July

March 1, 2019 -  "Pain Rounds with Dr. D" features interviews and demonstrations with established experts from academia and private practices around the country. Topics will include challenging lead placement, surgical skills, management of complications, patient selection, the evidence behind spinal cord stimulation, case-based scenarios, professional development, and more.

“Pain Rounds with Dr. D” is a video curriculum and research project on the fundamentals of neuromodulation from The Johns Hopkins Department of Anesthesiology, the Division of Pain Medicine and Dr. Shravani Durbhakula. It is a free series (password protected and by subscription only). Fellows who enroll will be expected to view the complete video series and fill out pre/post surveys for research purposes. (Johns Hopkins)

Study Evaluates Longterm Outcomes of Spinal Cord Stimulation in Patients with Critical Limb Ischemia

Feb. 22, 2019 - Co-authors in Russia evaluated one-year outcomes of spinal cord stimulation in patients with critical limb ischemia to see the influence of clinical determinants and factors related to systemic atherosclerosis. (Annals of Vascular Surgery)

Company Submits Sacral Neuromodulation Data for Its Premarket Approval Application

Feb. 26, 2019 - Axonics Modulation Technologies announced that, as an amendment to its premarket approval application, it has submitted clinical data to the FDA about its sacral neuromodulation system for the treatment of urinary and bowel dysfunction. (Business Wire)

Company Announces Insurance Coverage Decision for Vagus Nerve Stimulator to Treat Episodic Headache

Feb. 26, 2019 - The device company electroCore, Inc. announced an insurance coverage decision from Highmark for the company's noninvasive vagus nerve stimulator for abortive treatment of episodic migraine and episodic cluster headaches. The insurer serves more than 5 million patients in Pennsylvania, Delaware, and West Virginia. (Globe Newswire)

Draft Guidance Issued on Development of Brain-Computer Interfaces

Feb. 25, 2019 - The U.S. FDA has issued draft guidance that outlines recommendations for non-clinical testing and clinical study design related to development of brain-computer-interface (BCI) devices for paralyzed patients or amputees. These brain implants are intended to help provide some mobility or sense of touch. The draft guidance will be open for public comment. (Verdict Medical Devices)

Grant Supports Research Into Wireless Nerve Stimulation for Stroke Recovery

Feb. 20, 2019 - The Texas Biomedical Device Center announced a research grant from  of up to $3.5 million from the U.S. National Institutes of Health to support development of wireless nerve stimulation as an enhancement to stroke recovery. (Texas Biomedical Device Center)

Clinical Trial to Begin for Noninvasive Device to Potentially Treat Overactive Bladder

Feb. 25, 2019 - FemPulse Corporation announced plans for a safety-and-performance clinical trial of its non-implanted vaginal ring intended to deliver neurostimulation to help relieve symptoms of overactive bladder. (AP)

Article Compares Amount of Paresthesia in Pain Patients from Different Modes of Neurostimulation

Feb. 25, 2019 - A sub-analysis compared paresthesia coverage of patients' pain in dorsal root ganglion stimulation versus spinal cord stimulation. (Clinical Pain Advisor)

Data Presented at Meeting Concerning Noninvasive Device Investigated for Epileptic Seizures

Feb. 25, 2019 - Neuroelectrics Corporation presented results of its clinical trial of a noninvasive brain stimulation device intended to reduce the frequency of seizures in epilepsy. (Business Wire)

Device Company Founder Describes Path of Technology and Commercial Development

Fall 2018 - In an alumni magazine profile, a device-company founder describes her interest in closed-loop control systems -- initially from a motivation to help regulate insulin levels. The decision was made to start with pain control as the fastest and easiest "roadmap" to get the device on the market. Later, she envisions research into "modalities like thyroid control". (Lift)

Company Says CMS Has Modified a Coverage Decision about Vagus Nerve Stimulation

Feb. 21, 2019 - LivaNova announced the U.S. Centers for Medicare & Medicaid Services (CMS) issued a modified national coverage decision, through a CMS Coverage with Evidence Development framework, which will enable Medicare coverage for its vagus nerve stimulation for treatment-resistant depression when offered through a CMS-approved, double-blind, randomized, placebo-controlled trial with a follow-up of at least one year. (Mass Device)

Journal Article Details a Project to Develop a Closed-Loop, Peripheral, Neural Interface for an Amputee to Operate an Artificial Hand

Feb. 20, 2019 - A report in Science Robotics details a functional electrical stimulation project. In it, a 40-year-old woman in Rome, whose left forearm had been amputated more than two decades ago, was implanted with a peripheral neural interface designed to offer closed-loop control of bionic hands. The investigators included control algorithms intended to provide force and slippage sensations. (Science Robotics)

Company Announces U.S. Launch of Deep Brain Stimulation in Medically Refractory Epilepsy

Feb. 20, 2019 - Medtronic announced the U.S. launch of deep brain stimulation therapy for medically refractory epilepsy. (Globe Newswire)

Presentation Concerns Point-of-Care Ultrasound in Certain Pain Patients

Feb. 19, 2019 - Researchers presented early clinical data about applying ultrasound at point-of-care to potentially address pain in two conditions. (Pain Medicine News)

Article Summarizes Device Options for Headache Disorders

Feb. 18, 2019 - An overview of neuromodulation and stimulation devices for headache disorders says that an increase in device development brought forward additional treatment options. (Neurology Live)

Company Focused on Technology for Powering Neuromodulation Implants Completes $26 Million Series B Financing

Feb. 20, 2019 - Start-up Neuspera, which is pursuing development of power technology for neuromodulation implants, has closed a $12 million final round of its $26 million Series B equity financing. (Cision)

Company Files Pivotal Study Data with FDA

Feb. 20, 2019 - Axonics has filed interim clinical data with the FDA from its pivotal study of its sacral neuromodulation system for the treatment of urinary and bowel dysfunction. (NeuroNews)

First Patient Implanted in a Pilot Trial of Deep Brain Stimulation in Treatment-Resistant Post-Traumatic Stress Disorder

Feb. 18, 2019 - A woman with treatment-resistant post-traumatic stress disorder in Canada has become the first person in a pilot trial in Toronto to be implanted with a deep brain stimulation system targeting the subgenual cingulate system. The trial will enroll up to five people. (The Globe and Mail)

Neurostimulator Receives CE Mark to Treat Overactive Bladder

Feb. 18, 2019 - Bioness, Inc. announced its tibial nerve stimulator was approved to treat overactive bladder in Europe. (Cision)

Researchers Observe Vagus Nerve Stimulation Effect on Pain Processing

Feb. 13, 2019 - Healthy volunteers were exposed to a painful heat stimulus while undergoing scans of brain activity in a study of vagus nerve stimulation (VNS) effects, prior to an investigation of VNS in military veterans who have post-traumatic stress disorder. (Pain News Network)

Grant Will Fund Feasibility Study of Noninvasive Brain Stimulation in Addiction

Feb. 13, 2019 - Soterix Medical Inc. announced it has been awarded a Small Business Research Innovation Research grant of $475,000 from the National Institute of Drug Abuse of the National Institutes of Health, for a feasibility study of its self-administered system for transcranial direct current stimulation to potentially reduce craving for cocaine. (Cision)

Researchers Investigate Noninvasive Brain Stimulation for Epilepsy

Feb. 11, 2019 - A research project in the Netherlands is investigating noninvasive brain stimulation as a potential therapy for epilepsy. (Medical Xpress)

Company Announces a New Category / CPT Code for Its Responsive Neurostimulation System

Feb. 13, 2019 - NeuroPace announced that the American Medical Association has issued a new reimbursement code for review and interpretation of brain-activity data from its neurostimulation system that monitors and responds to focal epileptic seizures. The code went into effect Jan. 1, 2019. (NeuroNews)

Company Seeks Full-Body Conditional FDA Labeling for Its Sacral Neuromodulation System

Feb. 12, 2019 - Axonics has submitted data to the FDA to seek full-body conditional MRI labeling for its sacral neuromodulation system. (Seeking Alpha)

Publication Profiles North American Chapter President

Feb. 8, 2019 - The North American Neuromodulation Society president, Todd Sitzman, MD, is featured in a profile by the publication NeuroNews. (NeuroNews)

FDA Clearance Announced for Noninvasive Stimulation for Migraine Pain

Feb. 6, 2019 - The company electroCore LLC announced it has received an expanded FDA clearance for use of its noninvasive vagus nerve stimulator as an acute treatment for migraine pain in adults. (Pain Medicine News)

Article Features Patient who Received a Neurostimulation Implant for His Digestive Condition

Feb. 7, 2019 - An article profiles a man with gastroparesis in the U.K. who was implanted with a gastric electrical stimulator two months ago. (Daily Mail)

Observational Study Follows Recipients of Spinal Cord Stimulators

Feb. 7, 2019 - A prospective observational study that followed 402 patients for two years who had received a spinal cord stimulator was published in the European Journal of Pain. (Clinical Pain Advisor)

Company Announces Software Approval for Drug Delivery Device

Feb. 6, 2019 - Flowonix Medical announced FDA approval of clinician programmer software for its Prometra intrathecal infusion system. (Drug Delivery Business News)

Visual Prosthesis Undergoes Clinical Trial

Feb. 6, 2019 - An article describes a visual prosthesis undergoing clinical study in Australia in seven patients who have retinitis pigmentosum. (ZD Net)

Neurofeedback Studied in Parkinson's Disease Patients

Feb. 6, 2019 - Osaka University researchers published clinical research in eNeuro concerning neurofeedback for Parkinson's disease patients. (News-Medical Life Sciences)

Implant Unveiled in Patient with Amputated Hand

Feb. 5, 2019 - A patient with an amputated hand in Sweden has received an implant designed to operate a prosthesis. (Industry Europe)

Canadian Province to Provide More Deep Brain Stimulation Access for Parkinson's Disease Patients

Feb. 5, 2019 - The province of British Columbia, Canada, announced plans to increase access to deep brain stimulation for patients with Parkinson's disease with recruitment of an additional neurosurgeon. The province will provide for 72 surgeries in the coming fiscal year. There are 70 patients on a wait list for the surgery. (CBC)

Agency Reconsiders Coverage of Vagus Nerve Stimulation for Depression

Feb. 5, 2019 - An article anticipates an agency decision about Medicare and Medicaid coverage of implanted vagus nerve stimulators for patients with treatment-resistant depression. (MedTech Dive)

Neurostimulation Study Concentrates on Predominant Lower Back Pain

Feb. 1, 2019 - A study compared medical management alone and medical management with spinal cord stimulation for predominant lower back pain in failed back surgery syndrome patients. (Pain)

Article Surveys Current and Potential Opportunities for Canadian Patients with Depression to Use Repetitive Transcranial Magnetic Stimulation

Feb. 3, 2019 - An article examines the potential to expand access to repetitive transcranial magnetic stimulation for depression in Canada. (Globe and Mail)

Study Tracks Cognitive Function of Parkinson's Disease Patients after Deep Brain Stimulation

Feb. 1, 2019 - An observational study in Germany looked at Parkinson's disease patients who received deep brain stimulation, some of whom also had mild cognitive impairment, and tracked the progression to dementia in some of the patients. (Parkinsons News Today)

Researchers Investigate the Effects of Non-Invasive Nerve Stimulation on Tremor

Feb. 1, 2019 - Researchers published findings about transcutaneous alternating current stimulation of peripheral nerves and tremor. They also investigated placing the electrodes on the scalp above the motor cortex, and the effect of a topical anesthetic during that stimulation. (IEEE Spectrum)

Company Raises $8 Million in Series C Funding

Jan. 31, 2019 - According to an SEC filing, SPR Therapeutics has raised $8 million of a $20 million Series C round of funding that began in January. (Mass Device)

Device Company Launches Spinal Cord Stimulation System in Europe

Jan. 31, 2019 - Boston Scientific Corporation has launched the Spectra WaveWriter spinal cord stimulation system in Europe. (NeuroNews)

Paper: Epidural Spinal Cord Stimulation Helped Restore Movement for Two Paralyzed Patients in Their 50s - 60s

Jan. 31, 2019 - Researchers published about using epidural spinal cord stimulation to restore movement in two women who had paralysis-inducing spinal cord injury five and 10 years ago, respectively. (EurekAlert)

Study Investigates Non-Invasive Brain Stimulation to Address Negative Schizophrenia Symptoms

Jan. 30, 2019 - Researchers investigated transcranial magnetic stimulation to reduce negative symptoms in schizophrenia. (Science Daily)

FDA Requires Additional Time to Review a Pre-Market Approval Application

Jan. 30, 2019 - Nuvectra announced the FDA will extend its review period for the pre-market approval of the company's sacral neuromodulation system, past the 180-day deadline. (BioPortfolio)

Column Details Recovery and Early Stages of Deep Brain Stimulation Therapy

Jan. 29, 2019 - A woman describes her early months following deep brain stimulation surgery for Parkinson's disease. (Pendleton Times Post)

Company Receives CE Mark for MRI-Conditional Labeling of Neurostimulation System

Jan. 29, 2019 - Abbott has received CE mark approval for MRI-conditional labeling of its Infinity deep brain stimulation system. (NeuroNews International)

Study Evaluates Overactive Bladder Patients' Medication Use after Sacral Neuromodulation

Jan. 25, 2019 - A study found that more than 80% of overactive bladder patients who progressed to sacral neuromodulation discontinued their medications for the condition. (Journal of Urology)

Non-invasive Brain Stimulation Being Studied to Augment Therapy for Stuttering

Jan. 26, 2019 - A clinical trial at the University of Oxford in the U.K. will explore transcranial direct current stimulation and training in verbal fluency as a possible therapy for stuttering. (The Guardian)

Column Considers the Future of Neuromodulation

Jan. 25, 2019 - In a column, Prof. Dirk De Ridder, MD, PhD, discusses how the future of neuromodulation should include three things: better understanding of the brain; better technology; and artificial intelligence to develop "smart" neuromodulation therapy. (NeuroNews)

Paper Analyzes Published Studies of Interventional Treatment for Obsessive Compulsive Disorder

Jan. 24, 2019 - A meta-analysis of published studies compared the effectiveness of neuroabaltion and deep brain stimulation for treatment-resistant obsessive compulsive disorder. (British Medical Journal)

New Guidance Issued by NICE Concerning a Form of Spinal Cord Stimulation

Jan. 23, 2019 - The U.K. National Institute for Health and Care Excellence, NICE, has introduced new guidance on a form of spinal cord stimulation as a treatment option for chronic neuropathic back or leg pain after failed back surgery. (NICE)

U.S. Spinal Cord Stimulation Training Survey Results Published

Jan. 22, 2019 - A survey of current and past fellows in pain management programs focused on the extent or nature of training in spinal cord stimulation implantation. (Regional Anesthesia and Pain Medicine)

Rechargeable, Directional Deep Brain Stimulation System Launched

Jan. 25, 2019 - Boston Scientific announced launch of the rechargeable Vercise Gevia deep brain stimulation system and Vercise primary cell for the treatment of symptoms of Parkinson's disease. (NeuroNews)

Data Reported on High-Frequency Peripheral or Spinal Cord Stimulation in Pain Patients

Jan. 24, 2019 - Clinicians at an Australian facility gathered data on pain scores for 12 months in patients implanted with high-frequency spinal cord stimulators or peripheral nerve stimulators. (NeuroNews)

Review Offers Updated Overview of Neurostimulation for Chronic Pain

Jan. 24, 2019 - An article on "Neurostimulation for Intractable Chronic Pain" reviews interventions, mechanisms of action, clinical indications, and suggests areas of future advancements. (Brain Sciences)

Neuromodulation Presented as a Health Technology that May Aid the Opioid Crisis

Jan. 23, 2019 - A healthcare technology business story presents neuromodulation as being considered a partial solution for the opioid crisis. The article says specialists believe it should be offered earlier in the treatment process. It adds that research is taking place to determine which patients benefit most from newer neurostimulation modes and devices. (STAT)

Studies Examine Burst Stimulation Mode in Pain Patients

Jan. 22, 2019 - Abbott released results from the BOLD study of intermittent burst stimulation, and discussed a second study of spinal cord stimulation patients. (Mass Device)

Foundation Issues Grant for Pre-surgical Customization of Neurostimulation for Epilepsy

Jan. 22, 2019 - The Epilepsy Foundation awarded a $150,000 grant to Greg Worrell, MD, PhD, professor of neurology and chair of clinical neurophysiology at Mayo Clinic, for development of a protocol during surgical evaluation to test electrical stimulation parameters to optimize and personalize therapy to enhance seizure control. (Cision)

Deep Brain Stimulation Recipient in India Plans a Regional Tour to Teach About Managing Parkinson's Disease

Jan. 19, 2019 - A Parkinson's disease patient in India who has taken two road trips since 2016, after receiving a deep brain stimulation system, is planning a 40-day road trip with his wife that will cover 2,600 km from Bengaluru to Kathmandu. Along the way, he will educate people on managing the disease for a better life. (Deccan Herald)

Researchers: Non-invasive Brain Stimulation Motor Effects Can Be Caused by Non-invasive Peripheral Nerve Stimulation

Jan. 17, 2019 - Researchers say they have isolated mechanisms showing the reported effects of transcranial alternating current stimulation on the motor system can be caused by transcutaneous stimulation of peripheral nerves. (Nature Communications)

Neurostimulation Company Releases Six-Month Study Data

Jan. 17, 2019 - Stimwave released six-month data from a trial of its spinal cord stimulation system in patients with back and leg pain, in which high or low frequency stimulation was used. (Mass Device)

First Patient Enrolled in Study of Intrathecal Drug Delivery in Pain Patients Who Were Weaned Off of Oral Opioids

Jan. 17, 2019 - Medtronic announced enrollment of the first patient in a study of the use of its intrathecal drug delivery device in people with chronic intractable non-malignant primary back pain who have been weaned off of oral opioids. (Drug Delivery Business News)

Annual Research Prize for Junior Investigators Announced

Jan. 16, 2019 - There is a March 15, 2019 deadline for junior investigators aged 45 or younger, who have received an advanced degree in the past 10 years, to submit an entry for the Science and PINS Prize in Neuromodulation. The $25,000 prize is based on an essay about research performed in the past three years. The award was started in 2016 by Science magazine and PINS Medical of China. In addition to the cash award, winners have their essay published in Science magazine. (Science 2.0)

Israeli Company Prepares for US. Stock Exchange Offering

Jan. 15, 2019 - Brainsway Ltd. has filed a prospectus for a public offering on Nasdaq to raise at least $30 million. Timing of the offering depends upon when approval of the prospectus is received from the U.S. Securities and Exchange Commission, which was affected by the U.S. government shutdown. (Globes)

Industry Observers Discuss the Role of Neuromodulation in Pain Treatment

Jan. 15, 2019 - A news feature about neuromodulation and pain presents viewpoints about a larger context for the treatment, with one physician saying neuromodulation can be part of the answer to part of the opioid problem, and that with individual patients, expectation management is important. (Mass Device)

Company Plans Patient Registry

Jan. 14, 2019 - Bioness, Inc. announced that for its peripheral nerve stimulator, it has launched a patient registry, to which patients will be able to opt-in to join. (Cision)

Industry Association Unveils an Updated Code of Ethics

Jan. 9, 2019 - AdvaMed, the Advanced Medical Technology Association, has published an updated Code of Ethics on Interactions with U.S. Health Care Professionals that will take effect January 1, 2020. It updates guidance about a number of aspects, such as consulting arrangements, and adds guidance about factors such as conduct of company representatives and information about on- and off-label use of medical devices. (Lexology)

Column Presents Top Takeaways from an Expert Consensus Published in 2018

Jan. 11, 2019 - A column summarizes the top 10 takeaways from the 2018 publication, "The Neuromodulation Appropriateness Consensus Committee on Best Practices for Dorsal Root Ganglion Stimulation." (NeuroNews International)

Review Summarizes Reports on Advanced Methods of Spinal Cord Stimulation

Jan. 9, 2019 - Updating a review from 2014, a newly published review summarizes reports from 2010 - 2018 on "Advanced methods of spinal stimulation in the treatment of chronic pain: pulse trains, waveforms, frequencies, targets and feedback loops." (Expert Review of Medical Devices)

Headache Symposium Includes Preliminary Results from a Clinical Trial of a Wearable Device to Treat Migraine

Jan. 9, 2019 - Remarks at the 4th Annual International Headache Symposium in Israel included preliminary results of a randomized, double-blind, parallel group, sham-controlled clinical trial of a migraine treatment device that stimulates the occipital and trigeminal nerves. (Business Wire)

Thought Leader Calls for Ottawa to Fund Better Mental Health Treatments

Jan. 9, 2019 - A medical columnist points out that more than 16 years after Health Canada approved repetitive transcranial magnetic stimulation for depression, the only provincial health authorities to cover the treatment are in Quebec and Saskatchewan. (Ottawa Citizen)

A Personal Account of Choosing Neurostimulation to Treat Peripheral Neuropathy Pain

Jan. 9, 2019 - A news feature tells the story of a man who developed peripheral neuropathy and chose neurostimulation rather than surgery to treat the chronic pain. (University of Kentucky)

Current Neuromodulation Treatments for Migraine Considered

Jan. 8, 2019 - An article summarizes the state of neuromodulation devices approved for migraine treatment. (Medscape)

Company Reports New Clinical Trials in Noninvasive Vagus Nerve Stimulation for Migraine

Jan. 8, 2019 - ElectroCore, Inc. announced two clinical studies focused on expanding the use of non-invasive vagus nerve stimulation for acute and preventive treatment of migraine. The company also noted publication of a retrospective analysis of the treatment in a clinical trial in cluster headache patients. (Globe Newswire)

Visual Prosthetic Meets Six-Month Endpoints in Feasibility Study

Jan. 8, 2019 - Pixium Vision reported interim six-month follow-up results of a feasibility study of its visual prosthetic implant, a wireless sub-retinal photovoltaic microchip, in patients with advanced dry age-related macular degeneration. (Pharmalive)

Researchers Study Effect of Transcranial Stimulation on Motor Behavior

Jan. 4, 2019 - Researchers at the University of Tokyo studied the effect of transcranial static magnetic field stimulation (tSMS) on motor behavior in healthy subjects. The stimulation modulates cortical excitability. The researchers compared ballistic pinch force control before, during and after tSMS and sham interventions. (Neuromodulation: Technology at the Neural Interface)

Multicenter Study Reports Five-Year Experience of Sacral Neuromodulation Therapy for Urinary Voiding Dysfunction

Jan. 4, 2019 - A group of co-authors report on a five‐year, retrospective, multicenter study in China that evaluated the long‐term safety and efficiency of sacral neuromodulation in patients with urinary voiding dysfunction. (Neuromodulation: Technology at the Neural Interface)

FDA Clears Sinus Pain Device

Jan. 3, 2019 - TIVIC Health systems Inc. announced 510(k) clearance from the FDA for its transcutaneous, hand-held neurostimulation device to treat sinus pain due to allergic rhinitis. (PR Newswire)

New Device Company Launches

Jan. 3, 2019 - Dr. V. Reggie Edgerton announced formation of SpineX, a Los Angeles-based medical device company developing non-invasive devices to stimulate the spinal cord. (Globe Newswire)

Journal Article Categorizes Intervention Complications

Jan. 3, 2019 - Co-authors categorized complications for dorsal root ganglion stimulation for pain relief, which were reported in the MAUDE (Manufacturer and User Facility Device Experience) database. (Regional Anesthesia & Pain Medicine)

Neurostimulation Company Divests Subsidiary Focused on Neuroscience Clinical Animal Research Technology

Jan. 2, 2019 - Nuvectra Corporation announced it has agreed to sell its subsidiary NeuroNexus Technologies, Inc. to NEL Group, Inc., for $5 million in cash. (Globe Newswire)

Last Updated on Thursday, December 05, 2019 05:56 PM