2021 News Briefs - International Neuromodulation Society

Earlier News:

Data Reported in Pilot Trial of Peripheral Nerve Stimulation in Postoperative Pain

April 15, 2021 - A pilot study assessed acute postoperative pain and opioid consumption in patients who received percutaneous peripheral nerve stimulation, compared to sham treatment. (Source: EurekAlert)

Pilot Trial Starts of Neuromodulation Device for Heart Failure

April 15, 2021 - Cardionomic, Inc. announced initial enrollment in Panama in a worldwide pilot study of its Cardionomic Pulmonary Neuromodulation System. The endovascular device stimulates the sympathetic nervous system via the pulmonary artery. The approach is based on early studies in which the stimulation increased cardiac contractility in chronic heart failure patients without significantly changing heart rate. (Source: SouthernMinn.com)

U.S. Medicare to Require Prior Authorization for Spinal Cord Stimulation

April 14, 2021 - Beginning July 1, the Centers for Medicare and Medicaid Services will require prior authorization for cervical fusion with disc removal and implanted spinal neurostimulators. (Source: Becker's Spine Review)

Researchers Assess Disparities in Access to Neuromodulation

April 14, 2021 - Researchers presented findings from a review of literature and surveys about disparities in access to neuromodulation therapy for women and underrepresented minorities. (Source: NeuroNews International)

Clinical Trial Starts of Spinal Cord Stimulation in Low Back Pain

April 14, 2021 - An article says a clinical trial, DISTINCT (Dorsal spInal cord STImulatioN vs mediCal management for the Treatment of low back pain), will begin in Nevada that compares spinal cord stimulation for pain to standard medical care. (Source: Las Vegas Review-Journal)

Evolution in Peripheral Nerve Stimulation for Pain

April 14, 2021 - An interview covers developments in peripheral nerve stimulation for pain. (Source: Pain Medicine News)

Patients from United Arab Emirates Start Using Abu Dhabi Facility to Receive Deep Brain Stimulation for Parkinson's Disease

April 13, 2021 - The first Parkinson's disease patients from the United Arab Emirates received deep brain stimulation implants in Abu Dhabi, where the service started last year. (Source: Gulf News)

Case Series Reports Outcomes in Pain Patients Following Peripheral Neurostimulation, With or Without a Preceding Trial

April 12, 2021 - A journal article details a retrospective case series of 72 patients who were treated with peripheral nerve stimulation (PNS) for chronic pain, 59 of whom received a preceding PNS trial. (Source: MD Linx)

Researchers Investigate the Effect of Occipital Neurstimulation on Putative Sensitization Factor in Migraineurs

April 12, 2021 - A small study compared aversive response to peripheral irritation with, and without, active occipital nerve stimulation in patients who have chronic migraine. The researchers suggest decreasing the effect of trigger factors might reduce central nervous system sensitization. (Source: Clinical Pain Advisor)

Corporation Acquires Manufacturer of Neurostimulation Implant for Heart Patients with Sleep Condition

April 12, 2021 - Zoll Medical Corporation has acquired Respicardia, Inc., and its implantable neurostimulators for the treatment of central sleep apnea in adults with reduced cardiac function. (Source: Business Wire)

Study: Neurostimulation in Patients with Refractory Overactive Bladder, from 2006 to 2019

April 11, 2021 - A publication reports findings in a study of sacral neuromodulation in 263 individuals with overactive bladder, including outcomes in patients who had failed botulinum toxin, compared with patients who had not received it. (Source: MD Linx)

Data Published on Noninvasive Neurostimulation in Pediatric Cerebral Palsy Patients

April 11, 2021 - A journal reports on combining transcranial pulsed current stimulation and transcutaneous electrical nerve stimulation to address lower limb spasticity in children with cerebral palsy. (Source: Medical Dialogues)

Technology Company Works on Wireless Brain-Computer Interface

April 9, 2021 - Neuralink posted a video of a macaque monkey using a video game controller through a wireless brain-computer interface under development by the company, which said its work builds on prior research. Coverage of the development referred to earlier work on brain-computer interface development in individuals with paralysis. (Source: Ars Technica)

Study Evaluated Noninvasive Vagus Nerve Stimulation in Hospitalized COVID-19 Patients

April 8, 2021 - Top-line results were released in a study designed to evaluate the safety and feasibility of noninvasive vagus nerve stimulation in addition to the current standard of care in patients hospitalized with active SARS-CoV-2 infection. (Source: Street Insider)

Potential Directions for Dorsal Root Ganglion Stimulation

April 7, 2021 - An interview discusses dorsal root ganglion stimulation for pain. (Source: Pain Medicine News)

Clinicians Report on Deep Brain Stimulation in Obsessive Compulsive Disorder

March 29, 2021 - A paper presents findings from a study of deep brain stimulation that targeted the bed nucleus of the stria terminalis in nine patients with treatment-resistant obsessive compulsive disorder. (Source: Translational Psychiatry)

Noninvasive Brain Stimulation Treatment for Depression in Patients with History of Childhood Trauma

March 29, 2021 - A presentation summarized findings in patients with certain types of childhood trauma and their response to transcranial magnetic stimulation for depression. (Source: Psychiatry & Behavioral Health Learning Network)

Study: Closed-Loop Spinal Cord Stimulation in Pain Patients

March 26, 2021 - Final 24-month results were published in the Avalon study of closed-loop spinal cord stimulation in chronic pain patients. (Source: Pain Practice)

Study Investigates Treatment of Painful Diabetic Neuropathy with Spinal Cord Stimulation

April 5, 2021 - A randomized clinical trial compared 10 kHz spinal cord stimulation with conventional medical management in patients with medically refractory painful diabetic neuropathy. (Source: JAMA Neurology)

Review Considers Use of Functional Electrical Stimulation to Improve Gait After Stroke

April 2021 - A review was published to guide clinical decision-making about the use of ankle-foot orthosis or functional electrical stimulation after stroke . (Source: Journal of Neurologic Physical Therapy)

In Merger, Device Company Becomes a Wholly Owned Subsidiary

March 30, 2021 - Bioventus Inc. has acquired the peripheral nerve stimulation device company Bioness, Inc. for $45 million up front, and $65 million in milestone contingency payments. (Source: Globe Newswire)

Researchers Study Noninvasive Brain Stimulation and Suicide Reduction in Depressed Patients with PTSD

April 1, 2021 - An article summarizes a study published in Neuromodulation that investigated multimodal elements of suicidality reduction after transcranial magnetic stimulation in patients with PTSD and depression. (Source: NeuroNews)

Company Receives Breakthrough Designation for Noninvasive Neurostimulation Device

March 23, 2021 - EncoraTherapeucs announced FDA Breakthrough Device designation for its tremor-reduction wearable device. (Source: Encora)

Company Announces Breakthrough Device Designation

March 31, 2021 - Neuropace, Inc. announced Breakthrough Device designation from the FDA for the potential use of its RNS system to treat idiopathic generalized epilepsy. (Source: Street Insider)

Article Addresses Choices of Neurostimulation Targets for Chronic Pain

March 31, 2021 - An interview covers when to choose neurostimulation other than spinal cord stimulation. (Source: Pain Medicine News)

Company Developing Graphene Brain Interface Announces $17 Million in Funding

March 30, 2021 - Spain-based INBRAIN Neuroelectronics S.L., founded in 2019 and working on medical device therapy for epilepsy and Parkinson's disease, announced $16.8 million in Series A funding. The funding will be used in its clinical research program concerning graphene-based electrodes. (Source: BioSpace)

Company Announces Expanded Service Life of Neurostimulation Component

March 25, 2021 - Nalu Medical's micro-implantable pulse generator has received FDA clearance for an expanded service life of 18 years. (Source: Yahoo Finance)

Neurostimulator Gains FDA De Novo Device Approval

March 30, 2021 - The FDA has given Helius Medical’s Portable Neuromodulation Stimulator approval for short-term treatment of gait deficit due to multiple sclerosis. (Source: FDA News)

U.S. Medical Center Adds Remote Programming for Deep Brain Stimulation Systems

March 29, 2021 - Rush University Medical Center in Chicago began offering a telemedicine video chat to remotely adjust treatment settings on deep brain stimulation systems. (Source: Newswise)

Practitioners Discuss Neurostimulation for Chronic Pelvic Pain

March 24, 2021 - Brief interviews of pain management physicians focus on newer research into neurostimulation for chronic pelvic pain. (Source: Pain Medicine News)

Clinicians Report Experience with Remote Spinal Cord Stimulation Programming

March 22, 2021 - An article in Neuromodulation describes the use of remote programming for spinal cord stimulations in patients with chronic pain during the COVID-19 outbreak in China. (Source: DocWire News)

Company Announces CE Mark Approval for Neurostimulator Component

March 22, 2021 - Medtronic announced CE mark approval for its SenSight directional lead system for deep brain stimulation. (Source: Mass Device)

Company Announces CE Mark Approval for Neurostimulator Component

March 22, 2021 - Medtronic announced CE mark approval for its SenSight directional lead system for deep brain stimulation. (Source: Mass Device)

Interview Discusses Brain Stimulation Technologies' Effect on Memory

March 20, 2021 - A radio interview talks about research into effects of noninvasive brain stimulation on memory, and the potential to help improve conditions like Alzheimer's disease and dementia. (Source: KCRW)

Patient is First in Arkansas to Receive Deep Brain Stimulation for Epilepsy

March 19, 2021 - The first deep brain stimulation surgery for epilepsy was conducted in Arkansas in a patient who had been using vagus nerve stimulation for the condition. (Source: UAMS News)

Lung-Pacing Company Receives Breakthrough Device Designation

March 18, 2021 - The privately held startup Stimdia Medical Inc. announced Breakthrough Device Designation from the U.S. FDA for its neurostimulator to aid in weaning patients from mechanical ventilation. (Source: Odessa American)

Company Announces Updated Spinal Cord Stimulator Labeling

March 17, 2021 - Medtronic announced the FDA approved updated device labeling to include study outcomes from a multicenter randomized control trial. (Source: PR Newswire)

Researchers Investigate Spinal Cord Stimulation in Painful Peripheral Neuropathy

March 17, 2021 - An interview covers research into spinal cord stimulation for painful peripheral neuropathy. (Source: Pain Medicine News)

Study: Data Show Disparities in Treatment with Neurostimulation for Pain

March 16, 2021 - Research published in Neuromodulation is summarized concerning an investigation into racial and socioeconomic disparities in spinal cord stimulation in patients who were covered by Medicare and/or Medicaid insurance.  (Source: Docwire News)

University Receives Grant to Develop Epidural Spinal Cord Stimulation for Spine-Injured Patients

March 15, 2021 - The National Institute of Neurological Disorders and Stroke has given the University of Louisville a $7.8-million grant under the U.S. Brain Initiative to develop and test software for adapting a commercially available spinal cord stimulation system for use in epidural spinal cord stimulation in individuals with spinal cord injury, to regain more motion and bladder control. (Source: News-Medical.net)

Newer Procedure OK'd by FDA in Neurostimulation for Obstructive Sleep Apnea

March 15, 2021 - Inspire Medical Systems, Inc. announced FDA approval of a simpler surgical implant procedure for its neurostimulation device for the treatment of obstructive sleep apnea. (Source: StreetInsider.com)

Study: Factors Influencing Uptake of Deep Brain Stimulation for Obsessive Compulsive Disorder

March 12, 2021 - In a single-institution retrospective chart review, authors sought to identify factors hindering obsessive compulsive patients from receiving deep brain stimulation therapy. (Source: Frontiers in Surgery)

Review: Sacral Neuromodulation in Neurogenic Lower Urinary Tract Dysfunction

March 15, 2021 - A review and meta-analysis covers 20 years of scientific literature concerning safety and effectiveness of sacral nerve stimulation in neurogenic lower urinary tract dysfunctions. (Source: Physicians Weekly)

Review: Peripheral Neurostimulation's Proposed Pain-Relief Mechanisms

March 12, 2021- A review presents a proposed mechanism for pain relief from percutaneous peripheral nerve stimulation. (Source: Journal of Pain Research)

Deep Brain Stimulation Service to Be Established in Dublin, Ireland

March 11, 2021 - A functional neurosurgeon is establishing the first deep brain stimulation service in Dublin, Ireland, where patients previously had to travel to Belfast or the UK for the surgery. Some 40 patients are expected to begin receiving the implantation procedures in the late summer. (Source: Athlone Advertiser)

Trial Investigates Shorter Protocol for Minimally Invasive Neurostimulation Treatment of Overactive Bladder

March 11, 2021 - A prospective, randomized, sham-controlled trial studied comparative efficacy of a shortened treatment period of overactive bladder with percutaneous tibial nerve stimulation. The shortened period was 6 weeks, rather than the usual 12 weeks, and study participants received either active stimulation or sham during that time. (Source: Medical Dialogues)

Researchers Study Recruitment Issues in Clinical Trial of Deep Brain Stimulation for Depression

March 10, 2021 - Clinicians in Canada report on an analysis of challenges in recruiting patients with treatment-resistant depression for deep brain stimulation. (Source: Neuropsychiatric Disease and Treatment)

Interview Focuses on Spinal Cord Stimulation Modes

March 10, 2021 - An interview describes how multiple waveforms are increasing spinal cord stimulation options. (Source: Pain Medicine News)

Clinicians Share Radiation-Safety Practices and Knowledge

March 9, 2021 - A survey investigated radiation-safety practices and knowledge gaps among interventional pain treatment practitioners. (Source: Regional Anesthesia & Pain Medicine)

Researchers Report Data on Potential Biomarker for Personalized Neurostimulation in Parkinson's Disease

March 5, 2021 - As a potential biomarker of motor improvement during adaptive deep brain stimulation, clinicians assessed beta band activity in a Parkinson’s disease patient. (Source: European Journal of Neurology)

Study Compares Two Spinal Cord Stimulation Modes

March 9, 2021 - A study compared spinal cord stimulation in patients with axial back pain delivered at either at high frequency (10,000 Hz) or in 500 Hz burst mode. (Source: Pain Medicine News)

Article Considers Non-Opioid Intrathecal Pain Relief in a European Setting

March 9, 2021 - A review article discusses the Polyanalgesic Consensus Conference and potential for a set of European guidelines regarding use of ziconitide for intrathecal analgesia in Europe. (Source: Brain and Behavior)

Implanted Neurostimulator Launched in Australia for Chronic Low Back Pain

March 9, 2021 - Mainstay Medical launched an implantable neurostimulation system for chronic low back pain in Australia. (Source: Medical Device Network)

Company Announces Clinical Trial Data Concerning Neurostimulation in Alzheimer's Disease

March 9, 2021 - Cognito Therapeutics announced Phase 2 results of gamma frequency neuromodulation in Alzheimer's disease. (Source: Business Wire)

Neuromodulation Device Maker Updates App with Remote Programming

March 8, 2021 - Abbott announced it has updated its patient app, NeuroSphere, which allows remote communication and programming updates for deep brain stimulation or spinal cord stimulation therapy. (Source: MobiHealthNews)

Company Announces FDA Approval of Visual Prosthetic Components

March 5, 2021 - Second Sight Medical Products announced FDA approval of its Argus 2s Retinal Prosthesis System, consisting of ergonomically redesigned glasses and a more powerful video processing unit. The company said the system integrates with its implanted systems in patients with retinitis pigmentosa. (Source: Business Wire)

Research Paper Projects Potential Function of Retinal Implant

March 5,2021 - Scientists in Europe published a virtual reality program to simulate what patients who have retinitis pigmentosa might see with retinal implants they are developing. (Source: Neuroscience News)

Researchers Explore Potential Pain Modulation with Optogenetics

March 5, 2021 - Nanoscope Therapeutics, Inc. announced presentation of a paper about pain modulation using opsin-based neuromodulation therapy. (Source: Odessa American)

Article Describes Minimally Invasive Brain-Computer Interface

Feb. 28, 2021 - An article says a sensor implanted in a vein near the motor cortex "might just be the first intracranial brain-computer interface (BCI) designed for everyday home use, enabling paralysed patients to regain independence by controlling a laptop or mobile phone using their thoughts." (Source: Medium)

Article Highlights Advances in Treating Chronic Pain with Neuromodulation

March 5, 2021 - Neuromodulation therapy is featured in an article about the future of personal health and treatment of chronic pain. (Source: MediaPlanet)

Stroke Patient Works with Neurosurgeons to Control a Robotic Limb Brace

March 3, 2021 - Physicians at Jefferson University Medical Center are working with a stroke patient to try a brain-computer interface linked to a brace on his weakened left arm to restore more motor control over the limb. (Source: The Health Nexus)

Case Report Published of Obstructive Sleep Apnea Treatment

March 3, 2021 - Nyxoah SA announced publication of case from a study of its neurostimulator, descrbing the experience of a patient who had obstructive sleep apnea with complete concentric collapse. (Source: Globe Newswire)

ELITE Study Will Gather Post-Market Outcome Data for Rechargeable Sacral Nerve Stimulation System

March 3, 2021 - A post-market study of up to 200 patients at 40 centers will assess safety, performance, and long-term outcomes of the InterStim Micro system for sacral neuromodulation. (Source: Newswise)

Company Announces Upcoming Presentation Concerning Neurostimulation in Alzheimer's Disease

March 2, 2021 - Cognito Therapeutics announced clinical data will be presented in an online scientific meeting on March 12 about gamma frequency neuromodulation in Alzheimer's disease. (Source: Business Wire)

Noninvasive Stimulation Tested in Post-Infection Joint Pain

March 2, 2021 - In a sham-controlled randomized trial, clinicians analyzed the effect of alternate sessions of transcranial direct current stimulation on persistent joint pain. The study subjects were women who had been infected by the chikungunya virus. (Source: Brain Stimulation)

Sacral Nerve Stimulation Setting is Subject of Study

March 1, 2021 - A study evaluated the effect of sub-sensory amplitude settings in sacral nerve stimulation therapy for overactive bladder. (Source: Neurology Urodynamics)

Article Addresses Access to Spinal Cord Stimulation

March 3, 2021 - An interview covers some obstacles for pain patients to access spinal cord stimulation therapy. (Source Pain Medicine News)

Journal Article Summarizes Studies of a Neurostimulation Modality for Pain Conditions Beyond CRPS

March 2, 2021 - A systemic review in Neuromodulation summarized studies of dorsal root ganglion stimulation treatment for chronic pain beyond complex regional pain syndrome (CRPS). (Source: Clinical Pain Advisor)

Noninvasive Neurostimulator Receives FDA Clearance for Acute Migraine Pain

March 2, 2021 - The FDA issued clearance for a multichannel noninvasive brain stimulation device to treat acute migraine pain, Relivion from Neurolief. (Source: Medscape)

Report: Deep Brain Stimulation Operative Time Based on Imaging Method

March 2, 2021 - Authors present findings from a retrospective chart review about operative time based on stereotactic imaging types. The findings emanated from a quality assurance study performed at an institution that changed from a deep-brain-stimulation-surgery imaging technique of post-implantation MRI to in-room CT. (Source: Surgical Neurology International)

Clinicians Propose Formalizing Recommendations for Physical Activity Following a Device Implant

March 1, 2021 - A letter proposes creation of consensus recommendations for physical activity following implantation of a neuromodulation device. (Source: American Academy of Pain Medicine)

Company Announces Distribution Agreement

March 1, 2021 - The company electroCore announced an exclusive distribution agreement in Australia for its noninvasive vagus nerve stimulator. (Source: StreetInsider.com)

Podcast About Neurosurgery and Cognition Focuses on Chronic Pain

Feb. 28, 2021 - In an interview about pain neurosurgery, Dr. Julie Pilitsis refers to chronic pain as tri-dimensional, involving sensory, cognitive, and emotional elements, saying that patients need holistic treatment from a multidisciplinary approach. (Source: Neurosurgery Podcast)

Review: Image Guidance for Deep Brain Stimulation Surgery

Feb. 26, 2021 - A review provides image guidance on deep brain stimulation surgery to treat Parkinson's disease. (Source: TBME)

Neurostimulation Device Maker Acquires a Therapeutics Company

Feb. 26, 2021 - Sacral nerve stimulator device-maker Axonics Modulation Technologies has acquired the company Contura, which developed a recently FDA-approved urethral bulking agent for overactive bladder. (Source: Medtech Dive)

Researchers Study Noninvasive Brain Stimulation and Opioid Craving

Feb. 26, 2021 - A transcranial magnetic stimulation study examined two brain areas for potentially reducing craving for opioids. The study also explored participants' pain levels. (Source: New-medical.net)

Analysis Explores Deep Brain Stimulation and Mood in Parkinson's Disease Patients

Feb. 25, 2021 - A meta-analysis examines mood changes after bilateral subthalamic deep brain simulation in patients with Parkinson's disease. (Source: Physician Weekly)

Researchers Make Data Available in Study of Stimulation and Emotional Self-Regulation

Feb. 24, 2021 - Scientists released a dataset of fMRI data associated with neurofeedback, to support research into using stimulation to reinforce self-regulation. (Source: Study Finds)

Authors Track Continuance of Percutaneous Tibial Nerve Stimulation for Bladder Condition

Feb. 24, 2021 - A study assessed rates of drop-out from continued percutaneous tibial nerve stimulation treatment for overactive bladder, compared to compliance with medical management.  (Source: Renal and Neurology News)

Article Features Experience with Treatment by Spinal Cord Stimulation for Abdominal Issues

Feb. 23, 2021 - Clinicians published a retrospective chart review of 26 consecutive patients who underwent a spinal cord stimulation trial for a primary diagnosis of nausea, vomiting, and refractory pain. (Source: Digestive Diseases and Sciences)

Noninvasive Neurostimulation Clinical Trial Completes Enrollment in COVID-19 Patients

Feb. 24, 2021 - The company electroCore has completed enrollment in a controlled trial of external vagus nerve stimulation in 110 adults with respiratory failure due to SARS-CoV-2 infection. (Source: MD+DI)

Magazine Article Features the Potential Emergence of Personalized Brain Stimulation Therapies for Mental Health Issues

Feb. 24, 2021 - A magazine article refers to recent research in obsessive compulsive disorder, and discusses possibilities concerning personalized brain stimulation therapy for issues such as depression. (Source: New York Times Magazine)

Physician Discusses Minority Diversity Issues in Access to Pain Therapies

Feb. 22, 2021 - In a video interview, Dr. Stephanie Vanterpool describes "how outreach can be used to address the disparities between white and underrepresented minority patients when it comes to accessing neuromodulation therapies." (Source: NeuroNews)

Video Explains Spinal Cord Stimulation Frequencies and Patterns

Feb. 24, 2021 - Two pain physicians from U.S. academic medical centers are interviewed in a three-minute video where they describe different spinal cord stimulation waveforms and stimulation patterns. (Source: Pain Medicine News)

Study Will Track Patients Who Begin a New Spinal Cord Stimulation Program

Feb. 24, 2021 - Celéri Health announced enrollment of the first patient in a study of long-term outcomes in up to 1,700 participants at 30 U.S. centers who plan to begin spinal cord stimulation treatment with Medtronic's differential target multiplexed programming. (Source: Globe Newswire)

Registry Data Documents Transcranial Magnetic Stimulation Treatment for Depression

Feb. 23, 2021 - Neuronetics announced publication of data from a clinical registry of 5,010 patients who were treated with two different protocols involving transcranial magnetic stimulation for depression. A standard protocol took 38.5 minutes and a shorter one took 18.75 minutes. (Source: Globe Newswire)

Study Assesses Levodopa Challenge in Two Deep Brain Stimulation Targets for Motor Disorder

Feb. 23, 2021 - A retrospective study assessed the value of short-term response to levodopa in predicting motor outcomes of Parkinson's disease patients following deep brain stimulation that either targeted the globus pallidus interna or the subthalamic nucleus. The study looked at factors such as tremor and patient age. (Source: AJMC)

Company Announces Implantation of 4th-Generation Deep Brain Stimulation System

Feb. 23, 2021 - The first U.S. Parkinson's disease patient has been implanted with a fourth-generation deep brain stimulation system from Boston Scientific. (Source: Parkinson's News Today)

Italian Startup Announces CE Mark for Its Deep Brain Stimulation System

Feb. 23, 2021 - The Italian spin-out Newronika announced it has received CE Mark approval for its deep brain stimulation system, AlphaDBS. The rechargeable system has a sensing technology that is under clinical evaluation that records local field potentials during stimulation. (Source: PR Newswire)

Percutaneous Nerve Stimulation Trialled for Low Back Pain

Feb. 22, 2021 - Investigators report a prospective, multicenter clinical trial of percutaneous peripheral nerve stimulation of medial branch nerves for chronic low back pain following lumbar radiofrequency ablation. (Source: Pain Medicine)

Neurostimulation Device Maker Announces Financing Round

Feb. 17, 2021 - Mainstay Medical announced it has closed an equity financing worth gross proceeds of $108 million. (Source: Mass Device)

Expanded MRI-Conditional Labeling Announced for Sacral Neuromodulator

Feb. 18, 2021 - Expanded labeling was approved by the FDA  for Medtronic’s InterStim II and InterStim Micro sacral neuromodulation systems that use SureScan MRI leads. (Source: Healio Neurology)

Clinicians Look at Pre-Seizure Autonomic Nervous System Feature and Neurostimulation Response in Patients with Drug-Resistant Epilepsy

Feb. 18, 2021 - Investigators studied pre-seizure heart rate variability in epilepsy patients to see if that is correlated with response to vagus nerve stimulation therapy. (Source: European Journal of Epilepsy)

Neuroradiologist Considers Emerging Neuromodulation Techniques

Feb. 18, 2021 - An interview with a neuroradiology professor mentions potential future integration of neuromodulation and neurointervention for therapy applications. (Source: NeuroNews)

Sleep Disorder Researchers Report on Monitoring of Apnea Patients Who Have an Implanted Neurostimulator

Feb. 18, 2021 - An article summarizes a published case series about overnight pulse oximetry for titration of hypoglossal nerve simulation in patients with obstructive sleep apnea. (Source: Healio)

Article Sets Forth Patient-Selection Considerations Regarding Deep Brain Stimulation for Tourette Syndrome Patients

Feb. 16, 2021 - Clinicians present current principles of patient selection in deep brain stimulation for Tourette syndrome, and raise future considerations. (Source: Neurology)

Investigational Noninvasive Device for Stroke Recovery Receives Breakthrough Device Status

Feb. 11, 2021 - The Israeli startup BrainQ announced its investigational stroke recovery device, which delivers a frequency-tuned low intensity electromagnetic field, has received Breakthrough Device designation from the U.S. FDA. (Source: PR Newswire)

Meta-Analysis Explores a Cost-Effective Threshold for Emerging Parkinson's Disease Treatment

March 2021 - Based on articles from 1998 - 2018, a team of authors analyzed utility and cost-effectives of treatment procedures, including deep brain stimulation, for Parkinson's disease. (Source: Neurosurgery)

Noninvasive Neurostimulator Receives FDA Approval for Adolescent Migraineurs

Feb. 17, 2021 - The FDA expanded clearance of electroCore's noninvasive vagus nerve stimulator for acute and preventive treatment of migraine to include adolescents aged 12 - 17, in addition to adults. (Source: MPR)

FDA Approves a Third-Generation Sacral Nerve Stimulator

Feb. 17, 2021 - Axonics received supplemental premarket approval from the FDA for its third-generation neurostimulator to treat urinary and bowel dysfunction. (Source: FDA News)

Review Considers Range of Neurostimulation Options for Chronic Disabling Low Back Back

Feb. 17, 2021 - A review centers on management of chronic disabling low back pain and rapidly evolving neurostimulation options. (Source: Journal of Pain Research)

Practitioners Surveyed on Battery Life of Deep Brain Stimulation Devices

Jan. 26, 2021 - An article presents observations concerning trends in battery life of deep brain stimulation devices. (Source: Movement Disorders)

Interview Offers an Overview of the Development of Neuromodulation for Chronic Pain

Feb. 15, 2021 - A Q&A interview covers the evolution of neuromodulation therapy for chronic pain and possible directions in its further development and application, and considers the perspective of patients and providers. (Source: Pain Medicine News)

Company Announces Neuromodulation Research Funding

Feb. 15, 2021 - In a deal that provides researchers with opportunities to study neural biomarker technology, BIOS, a Cambridge, U.K. startup, announced $900,000 funding over 12 months from the U.S. National Institutes of Health's Stimulating Peripheral Activity to Relieve Conditions (SPARC) program; a potential second-year award could bring the total funding from SPARC to about $1.4 million. Source: Business Weekly)

Researchers Try 3D Model to Optimize Neurostimulation for Pain Patients

Feb. 8, 2021 - Researchers investigated creation of a patient-specific predictive model for programming coverage of tonic spinal cord stimulation, using on magnetic resonance imaging from two patients. (Source: Journal of Neural Engineering)

Implant Studied to Address Vestibular Balance Disorder

Feb. 11, 2021 - The New England Journal of Medicine published an early feasibility study of an implanted vestibular protheses in individuals with instability and vision issues based on loss of vestibular hair cell function. (Source: Medical Xpress)

Authors Report on Prevalence of Pelvic Floor Symptoms in Women with Parkinson's Disease

Feb. 11, 2021 - Physicians who surveyed women with Parkinson's disease and age-matched controls investigated the extent of self-reported pelvic floor symptoms, including any beyond what may have previously been reported to a healthcare provider. (Source: Journal of Parkinson's Disease)

Article Presents Data on Painkiller Consumption Following Neuromodulation Therapy

March 2021 - In a retrospective analysis, 67 patients who had a trial or permanent spinal cord stimulator were evaluated for changes in opioid consumption. (Source: Pain Management)

Clinical Trial Assesses Noninvasive Vagus Nerve Stimulation in Stroke

Feb. 2, 2021 - The company electroCore announced completion of a 68-person enrollment in a double-blind, randomized, sham-controlled, Phase 2 trial in Turkey to assess safety and feasibility of noninvasive vagus nerve stimulation as an acute method to decrease ischemic brain injury from stroke. (Source: BioSpace)

Company Announces FDA Conditional MRI Labeling

Feb. 9, 2021 - Nyxoah SA announced FDA approval for MRI conditional labeling of its hypoglossal nerve stimulation device, for obstructive sleep apnea, for full-body 1.5T and 3T diagnostic scans within approved parameters. (Source: Globe Newswire)

FDA Breakthrough Device Designation Announced for Neurostimulator Under Development for Migraine

Feb. 8, 2021 - Minnesota-based ShiraTronics, Inc. announced FDA breakthrough device designation for a neurostimulation device for chronic migraine. (Source: PR Newswire)

Study Investigates Minimally Invasive Neurostimulation for Urinary Symptoms in Parkinson's Disease Patients

Feb. 8, 2021 - An article summarizes a study of percutaneous posterior tibial nerve stimulation in 76 Parkinson's disease patients with detrusor activity, who underwent a tapering protocol over 24 months. (Source: MD Linx)

Noninvasive Brain Stimulation Device Company Announces Acquisition

Feb. 5, 2021 - Flow Neuroscience has acquired the assets of brain stimulation technology developer Halo Neuroscience pertaining to potential treatment of depression and other mental health disorders. (Source: Medical Device Network)

Company Announces Closed-Loop Deep Brain Stimulation Implantation

Feb. 4, 2021 - Newronika, which was spun out from Italian neurological research institutions, announced the first implantation of its adaptive closed-loop deep brain stimulation system, AphaDBS. (Source: PR Newswire)

Researchers Study Noninvasive Brain Stimulation and Memory

Feb. 4, 2021 - A study that used videos to prompt formation of memories about complex and realistic events evaluated the effect of transcranial magnetic stimulation on memory. (Source: Neuroscience News)

Article Presents Update on Access to Deep Brain Stimulation in British Columbia, Canada

Feb. 3, 2021 - An article says the British Columbia Ministry of Health is recruiting a second neurosurgeon to reduce waits for deep brain stimulation (DBS) surgery by Parkinson's disease patients, and that new equipment added in June 2019 has allowed the number of annual DBS surgeries to increase from 38 to 78. The article says improvements in access were advocated for by a patient who was able to receive a DBS system 17 months ago, two years after she was referred for the procedure to manage her Parkinson's disease. (Source: Salmon Arm Observer)

Company Announces Availability of a Neuromodulation Device Master File

Feb. 1, 2021 - Development partners will be able leverage platform technology that Cirtec Medical will make available in a Device Master File from intellectual property it obtained nine months ago from the FDA- and CE mark-approved Nuvectra Algovita Spinal Cord Stimulation System. The step follows a sponsor-initiated withdrawal of a premarket approval for the system. (Source: Cirtec Medical)

Study Reports Data on Noninvasive Brain Stimulation for Tinnitus

Jan. 30, 2021 - Researchers shared outcomes from a prospective longitudinal study of high-definition transcranial direct current stimulation in a large cohort of patients with tinnitus. (Source: Progress in Brain Research)

Paper Describes Noninvasive Neurostimulation Targeting Blood Pressure Regulation in Patients with Spinal Cord Injury

Jan. 28, 2021 - Collaborators in Switzerland and Canada published research in Nature about adapting epidural electrical stimulation of the spinal cord to control blood pressure after spinal injury. (Source: Expatica)

Review: Brain Stimulation Helps Shed Light on Obsessive Compulsive Disorder

Jan. 1, 2021 - A review focuses on research that could potentially shed light on the pathophysiology of obsessive compulsive disorder, the authors say, which they believe could advance its treatment. The research includes both functional imaging studies and treatment with invasive or noninvasive brain stimulation, both of which have bearing on a proposed disease model of increased activity in brain regions that form a cortico-striato-thalamo-cortical loop. (Source: American Journal of Psychiatry)

Company Partners with University to Develop Neurostimulator for Obstructive Sleep Apnea

Feb. 2, 2021 - Nyxoah announced a collaboration and exclusive licensing agreement with Vanderbilt University to develop next-generation neurostimulation technologies to treat obstructive sleep apnea. (Source: Globe Newswire)

Company Begins Enrollment in Its Clinical Trial of Vagus Nerve Stimulation for Arthritis

Feb. 1, 2021 - SetPoint Medical announced it has enrolled the first patient in a clinical trial of vagus nerve stimulation for rheumatoid arthritis. (Source: Globe Newswire)

Authors Report a Proof-of-Concept Study of Neurostimulation in Arthritis Patients

Feb. 1, 2021 - Investigators report on a prospective, multicenter, open-label, single-arm, proof-of-concept study of auricular vagus nerve stimulation during active, treatment-resistant, rheumatoid arthritis. In the study, 27 patients were followed for 12 weeks. (Source: Lancet)

Patient Discusses Symptom Improvement after Spinal Cord Stimulation

Feb. 1, 2021 - A woman with complex regional pain syndrome raised £35,000 for spinal cord stimulation surgery. (Source: LADbible)

Report Highlights Research into Predicting Brain Response to Electrical Stimulation

Feb. 1, 2021 -  Researchers used novel electrical stimulation wave patterns to map brain activity, then employed new machine-learning techniques to analyze the data to predict the outcome of stimulation across multiple brain regions. They hope their work will have therapeutic applications. (Source: Medical Xpress)

Data Presented About Directional Deep Brain Stimulation in Parkinson's Disease

Jan. 29, 2021 - A study in 234 Parkinson's disease patients who were followed for up to 12 months following implantation of directional deep brain stimulation leads targeting the subthalamic nucleus was subject to a presentation during the January meeting of the North American Neuromodulation Society. (Source: NeuroNews)

Column Describes Neurotechnology Investigating Treatment of Neurological COVID-19 Impacts

December 2020 - An industry publication describes how investigations into treatment of respiratory or inflammatory disorders with neurotechnology devices are turning toward neurological impacts of COVID-19. (Source: Neurotech Reports)

New Terminology Proposed for a Persistent Pain Condition

Jan. 27, 2021 - An accepted manuscript, available online, by an international committee offers rationale for Failed Back Surgery Syndrome being renamed Persistent Pain Syndrome, rather than Chronic Pain after Spinal Surgery, as suggested by the new International Classification of Disease, ICD-11, which has been accepted by the World Health Organization. (Source: Pain Medicine)

Noninvasive Vagus Nerve Stimulation Method to Undergo Clinical Trial for Certain Post-COVID Symptoms

Jan. 26, 2021 - Soterix Medical Inc. announced a new clinical trial of home-based auricular vagus nerve stimulation for post-COVID neuropsychiatric symptoms, like fatigue, headache, or anxiety. (Source: PR Newswire)

Obstructive Sleep Apnea Device Receives MRI Labeling

Jan. 26, 2021 - The company Nyxoah announced its neurostimulation implant to treat obstructive sleep apnea, Genio, has received CE mark magnetic resonance imaging conditional labeling, for full-body 1.5T and 3T MRI scans. (Source: Street Insider)

Review Discusses Current Spinal Cord Stimulation Options to Treat Chronic Pain

Jan. 24, 2021 - A review covers neurostimulation for intractable chronic neuropathic pain. (Source: Brain Sciences)

Noninvasive Stimulation Trialed for Analgesia Post-Surgery

February 2021 - Researchers report a pilot randomized controlled trial of auricular neurostimulation during recovery from colorectal surgery, including a subgroup analysis by age. (Source: Diseases of the Colon & Rectum)

Brain Stimulation Device Receives FDA Clearance for Migraineurs Aged 12 and Above

Jan. 25, 2021 - Theranica's remote neurostimulation device has received expanded FDA approval for children aged 12 and up, the company announced, to treat episodic and chronic migraine. (Source: Healio)

Cardiac Care Team Reports on Smartphone - Implant Magnetic Interaction

Jan. 25, 2021 - In a single-person study, Heart Rhythm published correspondence in which authors report being able to suspend activity of an implantable cardioverter defibrillator by holding an iPhone 12 over the implant. The article says the phone has a circular array of magnets around a central charging coil to accommodate the company's "MagSafe" accessories. The iPhone manufacturer Apple addressed the concern with support document guidance to keep the devices at least six inches apart. (Source: The Verge)

Study Investigates Noninvasive Brain Stimulation to Reduce Tremor in Essential Tremor Patients

Jan. 25, 2021 - In a study, researchers used transcranial alternating current stimulation to suppress tremor in patients with essential tremor. (Source: Medical Xpress)

Woman with Parkinson's Disease Recounts Her Experience as a Deep Brain Stimulation Patient

Jan. 24, 2021 - In a column, a Parkinson's disease patient in Vancouver, British Columbia gives a vivid description of her surgery for a deep brain stimulation system, and benefits she noticed. (Source: Globe and Mail)

Company Announces FDA Approval for Deep Brain Stimulation System

Jan. 22, 2021 - Boston Scientific announced FDA approval for its fourth-generation Vercise Genus deep brain stimulation system. (Source: Mass Device)

News Segment Features Man with Dystonia, Treated by Neuromodulation

Jan. 22, 2021 - A television segment follows up on a Pennsylvania man with dystonia who received a deep brain stimulation system 21 years ago - at the time, being the youngest person to do so, a couple of years before DBS received a humanitarian device exemption from the FDA for that condition. (Source: WPXI)

Missouri Man Describes Improvement in Parkinson's Disease Symptoms After Deep Brain Stimulation

Jan. 20, 2021 - An article features a man who was diagnosed with Parkinson's disease while pursuing agriculture during retirement, and received a deep brain stimulation system to help manage his symptoms. (Source: KTVO)

Study Evaluates Obsessive Compulsive Behavior Following Personalized Noninvasive Brain Stimulation

Jan. 19, 2021 - An article in Nature Medicine describes research into the effect of  transcranial alternating current stimulation on obsessive compulsive behavior. The stimulation targeted the orbitofrontal cortex, and was personalized to the intrinsic frequency of the reward network. (Source: HealthDay)

Study Explores "Personalized" Brain Stimulation for Depression

Jan. 18, 2021 - Nature Medicine reports on a proof-of-concept study of intracranial brain stimulation in a patient with depression. (Source: UCSF)

Researchers in Texas are Enrolling Patients with Cervical Spinal Cord Injuries in a Clinical Trial of Vagus Nerve Stimulation

January 2021 - A clinical trial of vagus nerve stimulation will investigate its effect in people with cervical spine injuries on movement and a sense of touch. (Source: UT Dallas)

Clinical Trial Will Examine Post-Surgical Neurostimulation for Pain Control

Jan. 15, 2021 - A randomized sham-controlled clinical trial will evaluate the effect of percutaneous peripheral nerve stimulation on postoperative opioid consumption following orthopedic surgery. (Source: Clinical Pain Advisor)

Overview Discusses Deep Brain Stimulation for Chronic Pain

Jan. 15, 2021 - An article recounts research into deep brain stimulation for chronic pain. (Source: Neurology Advisor)

Company Announces U.S. Launch of Spinal Cord Stimulator

Jan. 14, 2021 - Boston Scientific announced it has launched its WaveWriter Alpha spinal cord stimulator systems in the United States. (Source: Mass Device)

Clinical Trial Begins of Adaptive Deep Brain Stimulation in Parkinson's Disease

Jan. 14, 2021 - Medtronic announced the first enrollment in a clinical trial of adaptive deep brain stimulation (DBS) in Parkinson's disease, Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease (ADAPT-PD). (Source: Seeking Alpha)

Study Investigates Noninvasive Stimulation in Essential Tremor

Jan. 13, 2021 - Researchers report on the effect on essential tremor of transcranial cerebellar stimulation that is phase-locked to the tremor movement. (Source: Imperial College London)

Laboratory Research Demonstrates Injectable Brain Electrode

Jan. 13, 2021 - An international team reports wirelessly stimulating the brains of freely moving mice using injectable magnetoelectric nanoelectrodes activated by an external magnetic field. (Source: Science Advances)

Company Announces Breakthrough Device Designation from the FDA for Noninvasive Device for Alzheimer's Disease

Jan. 12, 2021 - Cognito Therapeutics announced its noninvasive neurostimulation device has received FDA Breakthrough Device designation for the treatment of cognitive and functional symptoms associated with Alzheimer’s disease. (Source: Argus Press)

Clinical Trial Starts of Noninvasive Neurostimulation for Upper-Extermity Rehabilitation after Spine Injury

Jan. 12, 2021 - ONWARD, formerly known as GTX Medical, announced patient enrollment has started in a trial of noninvasive spinal cord stimulation therapy in spine-injured patients who are undergoing rehabilitation for hand and arm function. (Source: Argus Press)

Company Announces Breakthrough Device Designation from the FDA for Noninvasive Device for Alzheimer's Disease

Jan. 12, 2021 - Cognito Therapeutics announced its noninvasive neurostimulation device has received FDA Breakthrough Device designation for the treatment of cognitive and functional symptoms associated with Alzheimer’s disease. (Source: Argus Press)

Clinical Trial Starts of Noninvasive Neurostimulation for Upper-Extermity Rehabilitation after Spine Injury

Jan. 12, 2021 - ONWARD, formerly known as GTX Medical, announced patient enrollment has started in a trial of noninvasive spinal cord stimulation therapy in spine-injured patients who are undergoing rehabilitation for hand and arm function. (Source: Argus Press)

Researchers Study Augmenting Upper-Limb Rehabilitation with Neurostimulation

Jan. 12, 2021 - Researchers combined noninvasive stimulation with physical rehabilitation of the hands and arms in spine-injured patients. (Source: UW Medicine)

Neuromodulation Centre Will Offer Noninvasive Brain Stimulation for Depression

Jan. 11, 2021 - Southern Health NHS Foundation Trust became the first in its region to offer depression treatment using repetitive transcranial magnetic stimulation, and one of the few health service trusts in England to launch a Neuromodulation Centre offering the treatment. An article says the service was "introduced earlier than planned due to the COVID-19 pandemic" to be available to people who struggle with mental health issues during the lockdown. (Source: Southern Daily Echo)

Neurostimulation Device Receives FDA Clearance

Jan. 11, 2021 - Spark Biomedical's wearable neurostimulator for treating opioid withdrawal received FDA clearance. (Source: FDA News)

Company Raises $38.5 Million for Device Trial in Amputation Pain

Jan. 7, 2021 - Neuros Medical, Inc. announced it raised $38.5 million in series BB financing to complete enrollment in a pivotal trial of its nerve-block technology in post-amputation pain. (Source: Neuros Medical)

Deep Brain Stimulation for Mild Alzheimer's Disease Receives Breakthrough Device Designation

Jan. 6, 2021 - Functional Neuromodulation Ltd. announced Breakthrough Device designation from the FDA for stimulation of the fornix using the Boston Scientific Corp. Vercise™ deep brain stimulation systems in patients aged 65 or older who have mild probable Alzheimer's disease that is not adequately controlled with medications. (Source: PR Newswire)

Company Announces Results of Trial of Noninvasive Brain Stimulation for Acute Migraine

Jan. 6, 2021 - Neurolief announced pivotal clinical trial findings from its study of an external brain stimulation system for self-treatment of migraine. The device stimulates occipital and trigeminal nerves. (Source: Business Wire)

Virtual Realty and Spinal Cord Stimulation Combined in Study of Patients with Chronic Leg Pain

Jan. 5, 2021 - A study explored combining spinal cord stimulation treatment for chronic leg pain with a virtual reality simulation that illuminates the patient's virtual leg when it receives treatment. (Source: WV News)

Implantation Starts in Obstructive Sleep Apnea Trial

Jan. 5, 2021 - Nyxoah S.A. announced the first patient was implanted in its pivotal study of a hypoglossal nerve stimulation device for obstructive sleep apnea. (Source: Street Insider)

Device Receives FDA Clearance for Withdrawal Symptoms

Jan. 4, 2021 - Spark Biomedical, Inc. announced FDA clearance of its transcutaneous auricular neurostimulation therapy for relief of opioid withdrawal symptoms. (Source: Globe Newswire)