2022 News Briefs - International Neuromodulation Society

Earlier News:

Billionaires Invest in Neuromodulation Company

Dec. 16, 2022 - Synchron, founded by Australian professors Tom Oxley and Nick Opie, has closed $110 million in Series C funding involving Bezos Expeditions, Gates Frontier, and ARCH Venture Partners. (Source: ZeroHedge)

Company's Noninvasive Brain Stimulation System Receives FDA Clearance for Depression

Sept. 6, 2022 - Magnus Medical, Inc. received clearance from the FDA for its SAINT™ transcranial magnetic stimulation system for adults with medication-resistant depression. (Source: Business Wire)

Study Estimates Costs to NHS in England of Spinal Cord Stimulation Screening Trials

Sept. 6, 2022 - A team of authors published a study estimating the budget impact for the National Health Service in England of screening trials for spinal cord stimulation for neuropathic pain. (Source: Frontiers in Pain Research)

Brain-Computer Interfaces Featured in News Column

Sept. 2, 2022 - A column about the "Future of Everything" describes current and potential future therapeutic applications of brain-computer interfaces, such as fighting depression or restoring speech in people with paralysis. (Source: Wall Street Journal)

Company Announces Insurance Coverage Updates for Spinal Cord Stimulation for Painful Diabetic Neuropathy

Sept. 1, 2022 - The device company Nevro announced positive coverage updates from U.S. healthcare insurance providers concerning the treatment of painful diabetic neuropathy with spinal cord stimulation. (Source: BioSpace)

Researchers in Sweden Use National Registry Data to Analyze Post-Neurostimulation Work Absences in Chronic Pain Patients

Aug. 31, 2022 - Researchers in Sweden used a large population sample from a national registry to analyze changes in sick leave and disability pension in patients from 2006-2017, before and after they were implanted with spinal cord stimulation for chronic pain, compared to a reference group. (Source: Medical Xpress)

Health Publication Provides an Overview of Spinal Cord Stimulation

Aug. 30, 2022 - A column gives an overview of spinal cord stimulation. (Source: Healthline)

Company Receives FDA Clearance for Its Noninvasive Brain Stimulation Treatment for Depression

Aug. 30, 2022 - BrainsWay received an expanded 510(k) clearance from the U.S. FDA for its H7 coil to deliver deep transcranial magnetic stimulation for the treatment of adults with major depressive disorder and anxious depression. (Source: Fierce Biotech)

Presentation Describes First U.S. Implantation of an Endovascular Brain-Computer Interface in a Clinical Trial Participant with Paralysis

Aug. 26, 2022 - A recent scientific presentation described the first implantation of Synchron's endovascular brain-computer interface as part of its U.S. COMMAND feasibility study in patients with severe paralysis. (Source: NeuroNews)

Eating Disorder Study Targets Brain's "Reward Center"

Aug. 29, 2022 - A 6-month pilot trial published in Nature Medicine https://www.nature.com/articles/s41591-022-01941-w followed two patients with binge-eating disorder who were implanted with a responsive neurostimulation system that monitored activity in the nucleus accumbens, detecting and interrupting signals that had been associated in prior studies with food cravings. (Source: Penn Medicine News)

Post-Stroke Study Uses Brain-Machine Interface

Aug. 27, 2022 - A research center in Tübingen, Germany is looking for patients with post-stroke hand paralysis to further study a rehabilitation training approach they recently published involving a brain-computer interface. In their approach, the participants mentally rehearse an impaired movement in conjunction with sensory feedback, using a brain-computer interface that controls a robotic orthosis. (Source: BioPrepWatch)

Paper Analyzes Data Concerning Transcranial Photobiomodulation

Aug. 25, 2022 - Researchers published an analysis of pooled data concerning safety and tolerability of transcranial photobiomodulation for mood and anxiety disorders. (Source: Brain & Behavior Research Foundation)

Directional Deep Brain Stimulation Leads Launched in India

Aug. 25, 2022 - The Medtronic plc subsidiary Medtronic Private Limited launched the SenSight™ directional lead system for deep brain stimulation for treatment of movement disorders and epilepsy in India. (Source: The Print)

Publication Profiles Man Undergoing Investigative Neurostimulation Treatment for Opioid Addiction

September 2022 - A magazine article profiles a participant in a four-person study at West Virginia University of deep brain stimulation for treatment-resistant addiction. (Source: Harpers's)

Researchers Analyze Deep Brain Stimulation Connectivity Patterns

Aug. 24, 2022 - A team of co-authors questioned if there may be multiple targets for a common network in publishing an analysis of brain connectivity patterns and outcomes in 10 patients who had received stimulation to different brain targets in order to treat therapy-resistant self-injurious behavior. (Source: Frontiers in Human Neuroscience)

Brain-Computer Interface Consortium Receives Research Grant

Aug. 25, 2022 - The European Innovation Council has provided a grant of nearly 6 million euros to a research consortium that is working on a brain-computer interface they hope will help study participants with locked-in syndrome to achieve quicker and more convenient communication, such as at home and in real time. (Source: Mirage.News)

Researchers Compare Three Different Deep Brain Stimulation Modes in Patients with Parkinson's Disease

Aug. 24, 2022 - In a study in patients with Parkinson's disease, researchers compared motor effects and estimated energy use of standard deep brain stimulation and two different forms of what they called ""temporally optimized patterned stimulation", one having low average frequency. (Source: Frontiers in Neuroscience)

Data Published from Pilot Study of Transcranial Magnetic Stimulation in Patients with Drug-Resistant Epilepsy

Aug. 17, 2022 - Clinicians report an open-label pilot study of continuous theta burst repetitive transcranial magnetic stimulation in seven study participants who have neocortical drug-resistant epilepsy. (Source: Frontiers in Neuroscience)

Article Presents a Bevy of Brain Computer Interface Companies

Aug. 24, 2022 - An article presents summaries of seven companies that are working to develop brain computer interfaces, which encompass either invasive or noninvasive systems. (Source: Mass Device)

Device Company Announces FDA Approval of Its Latest Spinal Cord Stimulation System

Aug. 23, 2022 - Abbott announced FDA approval of its next-generation burst-mode spinal cord stimulation system for the treatment of chronic pain. (Source: PR Newswire)

Peripheral Nerve Stimulation Guidelines for Chronic Pain Published

Aug. 23, 2022 - A review offers evidence-based clinical guidelines for the use of implantable peripheral nerve stimulation in the treatment of chronic pain. (Source: Journal of Pain Research)

Study: Noninvasive Brain Stimulation Enhanced Memory in Older Adults

Aug. 22, 2022 - Scientists used transcranial alternating current stimulation to two different targets in older adults, aged 65 - 88, and studied effects on working memory and later recall. The study in 150 subjects involved daily stimulation sessions over four days, with re-testing of a memory task after one month. (Source: Nature)

Committee Leadership Notes Progress and Remaining Challenges for Women in Neuromodulation

Aug. 19, 2022 - An article by members of the North American Neuromodulation Society's Women in Neuromodulation committee describes progress, and remaining challenges, in alleviating gender disparities in the field of neuromodulation from the standpoint of career progression and advancement for women practitioners and researchers. (Source: NeuroNews)

Center in India Offers Deep Brain Stimulation Program for Patients with Parkinson's Disease

Aug. 17, 2022 - Aster Medcity, a medical center in the southwest India city of Kochi, has become an active deep brain stimulation center in the region for patients with Parkinson's disease, reporting that it treated 50 patients in the last 15 months through a partnership with the medical device company Medtronic. (Source: BioSpectrum India)

News Outlets Purport Recent Discussions about a Potential Investment in a Brain-Computer Interface Company

Aug. 19, 2022 - According to news sources, the founder of Neuralink reportedly approached rival company Synchron over potentially making an investment in the brain-computer interface company. (Source: Mass Device)

Researchers Study Changes in Brain Metabolism in Patients with Depression Who Received Brain Stimulation Treatment

Aug. 19, 2022 - A study tracked brain metabolic changes in 10 patients with depression who were treated with deep brain stimulation over 12 months. (Source: Molecular Psychiatry)

Neurology Guideline Authors Comment on Recently FDA-Approved Neurostimulation Treatment for Painful Diabetic Neuropathy

Aug. 18, 2022 - Commenting on a clinical study analysis at 12 months, neurology guideline authors expressed a desire for independent, sham-controlled study of 10 kHz spinal cord stimulation in painful diabetic neuropathy, and were curious about reported neurologic function outcomes. (Source: Neurology Today)

Home Treatment with Noninvasive Brain Stimulation Studied in Stroke Survivors

Aug. 18, 2022 - A pilot study evaluated the feasibility and effectiveness of adding remotely supervised transcranial direct current stimulation to enhance home-based cognitive rehabilitation in stroke survivors. (Source: MedPage Today)

Device Company Reports U.S. Patent Office Activity

Aug. 17, 2022 - Axoinics, Inc. announced that the U.S. Patent Office has granted eight patents and allowed 12 patent applications in the last 12 months. The topics concern components of the company's sacral neuromodulation system for bladder and bowel dysfunction. (Source: Business Wire)

Noninvasive Brain Stimulation Studied in Parkinson's Patients with Postural Syndrome

Aug. 17, 2022 - Researchers in Italy published data about the use of noninvasive brain stimulation during rehabilitation therapy in Parkinson's disease patients who have Pisa syndrome, a pathological lateral flexion of the trunk. (Source: NeuroNews)

Investigators Publish Data about Opioid Usage Changes in a Case Series of Spinal Cord Stimulation Patients

Aug. 17, 2022 - A retrospective case series in Canada tracked opioid usage in patients with chronic back and neck pain who received spinal cord stimulation between 2017 and 2021. (Source: Practical Pain Management)

Man Reaches a Milestone in his Lengthy Time with an Implanted Brain-Computer Interface

Aug. 17, 2022 - A news feature focuses on a man with paraplegia who has had a brain-computer interface for more than seven years and three months, the longest of anyone. The electrode array in his motor cortex allows him to use his thoughts to control external devices such as a computer, video games, and a robotic arm. (Source: Wired)

Funding Opportunity Focuses on Behavior and Brain Activity

Aug. 17, 2022 - The National Institutes of Health BRAIN Initiative has issued a funding opportunity and announced an informational session in September. The Brain Behavior Quantification and Synchronization (BBQS) opportunity is described as supporting "the development of cutting-edge tools for simultaneous, multimodal measurement of behavior within complex environments and integration of these tools with simultaneously recorded brain activity in humans." (Source: NIH BRAIN Initiative)

Report Compares Response Time Between Older and Younger Adults Given Neurostimulation Treatment for Depression

Aug. 16, 2022 - A report in Frontiers in Aging Neuroscience based on data from more than 500 patients compared the speed of response in older versus younger adults who received repetitive transcranial magnetic stimulation for major depressive disorder. (Source: EurekAlert)

Ohio Company Conducted Proof-of-Concept Studies for Its Spinal Cord Stimulator Treatment

Aug. 11, 2022 - An article says Soin Neuroscience plans further clinical study after completing proof-of-concept studies for its spinal cord stimulator treatment in 20 chronic pain patients. (Source: London Post)

Study Investigates Presence of Skin Bacteria in Patients Seeking Spinal Cord Stimulation Treatment

Aug. 11, 2022 - At the 2022 North American Neuromodulation Society meeting, investigators presented a study of the prevalence of methicillin-susceptible and methicillin-resistant Staphylococcus aureus in spinal cord stimulation (SCS) patients. (Source: Pain Medicine News)

Minimally Invasive Neurostimulation Method Studied in Multiple Sclerosis Patients with Bladder Symptoms

Aug. 10, 2022 - Transcutaneous tibial nerve stimulation was tested in a proof-of-concept study in people who have overactive bladder due to multiple sclerosis. (Source: Multiple Sclerosis News Today)

Analysis: Parkinson's Disease Patients' Deep Brain Stimulation Outcomes Associated with Microelectrode Recordings

Aug. 10, 2022 - A pooled analysis assessed comparative outcomes in motor symptoms and medication usage in Parkinson's disease patients after they were implanted with deep brain stimulation systems with, or without, the use of microelectrode recordings during the procedure. (Source: Parkinson's News Today)

Authors Issue Guidance About Peripheral Nerve Stimulation Clinical Care

Aug. 7, 2022 - A team of authors reviewed pain management studies to prepare a guide for advanced practice providers on peripheral nerve stimulation. (Source: Journal of Pain Research)

Study Evaluates Noninvasive Brain Stimulation in Patients with Loss of Smell after COVID-19 Infection

Aug. 5, 2022 - A double-blind, sham-controlled study evaluated anodal transcranial direct current stimulation combined with olfactory training in seven patients who experienced loss of smell following COVID-19 infection. (Source: Neurology Advisor)

Small Study Investigated Auricular Vagus Nerve Stimulation in ICU Patients with COVID-19

Aug. 3, 2022 - In Austria, researchers conducted a prospective randomized study of the effect on inflammatory markers of percutaneous auricular vagus nerve stimulation in critical-care patients with severe COVID-19 infections who were about to receive artificial respiration. In the 10-patient study, half the patients were randomized to receive the stimulation treatment, while the others received standard-of-care treatment alone. (Source: EurekAlert)

Patent Issued for a Patterned Neuromodulation System

July 26, 2022 - A newly issued U.S. patent for work funded by the U.S. Defense Advanced Research Projects Agency covers an intraoral device to noninvasively stimulate facial and/or trigeminal nerves with temporally patterned electrical stimulation to improve waste clearance across the blood-brain barrier. (Source: Research Gate)

Science Competition Recognizes Noninvasive Brain Stimulation Research

Aug. 4, 2022 - The 2022 Science & PINS Prize for Neuromodulation went to a researcher at Boston University who submitted an essay about using transcranial alternating current stimulation to improve age-related memory decline through a personalized protocol in study participants aged 60 - 76 years old. (Source: AAAS)

A Guide to Electrical Stimulation for Overactive Bladder

July 28, 2022 - An article gives an overview of electrical stimulation for overactive bladder, describing percutaneous tibial nerve stimulation and sacral neuromodulation, and providing links to resources for patients. (Source: Healthline)

Company Announces Proof-of-Concept Study Has Become Eligible for Data Safety Monitoring

July 26, 2022 - SynerFuse announced is proof-of-concept study reached a milestone in which a data safety monitoring board will be able to review the concept. In the study, spinal fusion is combined with dorsal root ganglion stimulation. The company said the milestone is the fifth such implant having been completed. (Source: Becker's Spine Review)

Health Canada Approval Announced for Remote Programming App

July 26, 2022 - Abbott announced Health Canada approval for its NeuroSphere Virtual Clinic app that provides video chat with clinicians and remote programming for its neuromodulation technologies. (Source: Medical Design & Outsourcing)

Brain-Computer Interface Developer Reflects on Development of the Field

May 21, 2022 - The co-founder and chairman of Blackrock Neurotech, Florian Solzbacher, PhD, gave an interview about the field of brain-computer interfaces BCI) shortly after the company announced a research collaboration to develop portable BCI systems. (Source: Mass Device)

SPARC Program Announces Eight Phase I Winners of Neuromod Prize, Including for Spinal Cord Injury Research

July 25, 2022 - The National Institutes of Health's Stimulating Peripheral Activity to Relieve Conditions (SPARC) program announced eight Phase I winners of its Neuromod Prize, which focused on restoration of organ function and divided $800,000 among the eight winners, who can compete in proof-of-concept studies in a second phase of the competition. The winning projects focused on such issues as autonomic function after spinal cord injury; pain; urinary or GI tract function; cardiac function; and respiratory infections. (Source: PR Newswire)

Article: Lead Migration in Spinal Cord Stimulation

July 25, 2022 - In an interview, the author of a single-center study discussed findings of lead migration in spinal cord stimulation and possible applications of the findings to clinical practice. (Source: Pain Medicine News)

News Feature Highlights Brain-Interface Companies

July 25, 2022 - An article focuses on four companies that are developing brain-computer interfaces. (Source: STAT)

Company Announces FDA Clearance for Pain-Relief Device

July 21, 2022 - NeuraLace announced FDA clearance of its external peripheral nerve stimulation system for relief of neuropathic pain. (Source Fierce Biotech)

Data Reported on Deep Brain Stimulation in Tourette Syndrome

July 21, 2022 - A team of co-authors reported on deep brain stimulation to the subthalamic nucleus in 10 patients with refractory Tourette syndrome. (Source: Journal of Neurology)

Researchers Study Neurostimulation Method with an Application in Spinal Cord Injury

July 21, 2022 - Researchers carried out two studies involving 10 healthy participants to investigate peripheral nerve stimulation (PNS) in paired associative stimulation, which combines the electrical nerve stimulation with transcranial magnetic stimulation. PAS can help improve muscle activity and independence in incomplete spinal cord injury patients, and they sought to determine optimal PNS intensities. (Source: Scientific Reports)

Journal Article Presents Pilot Study of Deep Brain Stimulation for Alcohol Use Disorder

July 20, 2022 - Researchers published  a pilot study of deep brain stimulation of the nucleus accumbens in six participants who had severe chronic alcohol use disorder. (Source: Sunnybrook Research Institute)

Research Published About Peripheral Nerve Stimulation for Migraine

July 20, 2022 - A study evaluated the safety and effectiveness of combined occipital and trigeminal nerve stimulation in the acute treatment of migraine. (Source: Medical Dialogues)

Medical Center Announces NIH Grant for Neurostimulation Resarch in Chronic Pain

July 20, 2022 - UVA Health announced a grant of more than $5 million from the National Institutes of Health HEAL Initiative to fund a clinical trial of deep brain stimulation of sections of the insula to potentially treat refractory neuropathic pain in 12 patients. (Source: UVA Health)

Company Receives Additional Clearance for Noninvasive Brain Stimulation System

July 19, 2022 - Neuronetics announced the FDA has cleared its transcranial magnetic stimulation system to treat anxiety symptoms in adults who have major depressive disorder ("anxious depression"). (Source: Mass Device)

24-Month Data Presented for Closed-Loop Spinal Cord Stimulator

July 19, 2022 - Saluda Medical announced presentation of 24-month data from its EVOKE study, in which outcome measures for its closed-loop spinal cord stimulation device included pain relief as well as quality of life, functional status, sleep, and mood improvements. (Source: PR Newswire)

Neurostimulator Company Announces CE Mark Approval for Components of a Sleep Apnea Therapy Device

July 19, 2022 - Nyxoah SA received CE Mark approval for external components of its Genio 2.1 hypoglossal nerve stimulation system for obstructive sleep apnea. (Source: Yahoo)

Study Looks at Effects of Noninvasive Brain Stimulation Treatment for Depression in Older Patients Compared to Other Adults

July 19, 2022 - To investigate whether benefit varies by age, a multi-center study of more than 500 patients with depression compared the effects of repetitive transcranial magnetic stimulation in patients who were either under 65, or aged 65 and above. (Source: Medical Xpress)

Researchers Gather Data for a Difficult Condition as a Possible Precursor to Brain Stimulation Therapy

July 19, 2022 - An article describes preliminary research into overnight EEG monitoring of girls with Rett syndrome which the researchers believe may one day help guide possible brain stimulation therapy which might improve the typically variable developmental trajectory in these children. (Source: Boston Children's Hospital)

First U.S. Patient in Clinical Trial Receives Endovascular Brain Computer Interface

July 19, 2022 - Synchron announced it implanted the first patient in the U.S. with its Stentrode device, in a clinical trial that seeks to accomplish hands-free control of digital devices in people with severe paralysis. (Source: Mass Device)

Visual Prosthetics Company Announces Receipt of $1.1 Million Grant Funding

July 18, 2022 - Second Sight Medical Products, Inc. announced its fourth year of funding in a five-year grant from the National Institutes of Health. The company said the $1.1 million that was released by the agency will go toward costs of its Orion visual prostheses clinical trial. (Source: Business Wire)

Article Discusses Potential Brain Stimulation Mode

July 18, 2022 - An article says that low intensity focused ultrasound may eventually become a noninvasive brain stimulation method to help control symptoms of psychiatric disorders. (Source: MDLinx)

Specialists Call for Improved Access to Brain Stimulation Modality for Patients with Intractable OCD

July 15, 2022 - In an opinion article, 42 specialists call upon insurers and mental health providers to address what they call a "crisis of access" to deep brain stimulation therapy for people who have intractable cases of obsessive compulsive disorder. (Source: Nature Medicine)

Company Seeks to Expand Access to Neurostimulation Therapy for Multiple Sclerosis

July 15, 2022 - The medical device company Helius is offering online training for its noninvasive PoNS neurostimulator to multiple sclerosis therapists. The company plans to partner with neurologists and neurorehabilitation specialists at 10–12 U.S. institutions that have expressed an interest. In addition, the company launched a therapy access program for U.S. patients to run through Dec. 31. (Source: Multiple Sclerosis News Today)

Company Raises $16 Million for Pivotal Study of Neurostimulation for Weaning from Mechanical Ventilation

July 14, 2022 - Stimdia Medical Inc. announced it raised $16 million in the first tranche of a series B financing round. The company said the financing would support initiating a pivotal study for its neuromodulation technology intended to strengthen and condition the diaphragm in patients on mechanical ventilation. The Series B is designed to offer a total of $30 million in financing altogether. (Source: Business Wire)

Company Announces FDA Clearance of Neurostimulator for Diabetic Peripheral Neuropathy Pain

July 14, 2022 - Dyansys Inc. announced FDA clearance of its percutaneous electrical neurostimulation device for symptomatic relief of chronic, intractable pain from diabetic peripheral neuropathy. Worn behind the ear, the device delivers treatments for multiple days. (Source: PR Newswire)

Article Summarizes Trigeminal Nerve Stimulation Options in Migraine

July 14, 2022 - An article provides an overview of trigeminal nerve stimulation for migraine. (Source: Verywell Health)

Review: Consortium Members Advocate Study of Neuromodulation for COVID-19 Respiratory Concerns

July 14, 2022 - A team of authors published an overview to support scientific study of neuromodulation technologies' potential to treat inflammatory effects on respiration and lung function in COVID-19 infection. The authors co-founded the International Consortium on Neuromodulation for COVID-19 in April 2020. (Source: Frontiers in Neurology)

Researchers Study Noninvasive Vagus Nerve Stimulation in Post-Surgical Rebound Pain

July 14, 2022 – Researchers in China published a randomized, controlled study investigating transcutaneous auricular vagus nerve stimulation's effect on rebound pain in patients undergoing anterior cruciate ligament reconstruction under general anesthesia combined with preoperative femoral nerve block. (Source: Journal of Pain Research)

Company Receives a Patent for an Implanted Neurostimulator Intended to Treat Migraine

July 13, 2022 – A list of patent announcements includes an illustration of a newly patented implantable neurostimulation system intended for migraine. The patent is assigned to the private early stage company ShiraTronics, which was spun out of the technology accelerator NuXcel. (Source: Dallas Innovates)

Investigators Report Findings in Study of Sacral Neuromodulation in Patients with Neurogenic Bladder

July 7, 2022 - Investigators report a sham-controlled, double-blind, multicenter trial of sacral neuromodulation in neurogenic lower urinary tract dysfunction. (Source: NEJM Evidence)

Podcast Discussion Focuses on Evolution of Spinal Cord Stimulation Therapy and and Potential in Ischemic Disease

June 21, 2022 - A 30-minute interview in a series on "Neuromodulation Today and Tomorrow" covers the evolution and application of neuromodulation therapies, including conceptual possibilities for newer neurostimulation waveforms or combinations to potentially aid in the treatment of peripheral vascular disease. (Source: Machine Medicine)

Company Announces Its Neurostimulation System Received FDA Breakthrough Device Designation

July 12, 2022 - Abbott announced it received FDA breakthrough device designation for investigation of its deep brain stimulation system in the treatment of treatment-resistant depression. (Source: Mass Device)

Spinal Cord Stimulator Maps Motor Response

July 11, 2022 - An article with potential significance for focal lower extremity pain presents a study in 12 chronic pain patients in whom a high-resolution spinal cord stimulation paddle was used to map the location of responses in different dermatomes and sides, corresponding to placement of the paddle at 8 locations across the side or middle of the spinal cord. (Source: Neurosurgery)

The FDA Permits Device Company to Start a Clinical Trial in Obstructive Sleep Apnea

July 11, 2022 - Nyxoah SA has received FDA approval for a clinical trial to evaluate their hypoglossal neurostimulator in adults with obstructive sleep apnea and complete concentric collapse of the soft palate. (Source: Street Insider)

Companies' Collaboration Aims to Add Artificial Intelligence Analysis to Chronic Pain Therapy Data

July 8, 2022 - Boston Scientific and IBM Research are collating data from spinal cord stimulation studies in a bid to objectively analyze or monitor patients' chronic pain experiences. (Source: Yahoo! Entertainment)

Article Describes the Evolving Science of Brain Stimulation Therapies

July 8, 2022 - Neuroscience researchers point to preclinical and clinical studies while presenting views about the utility of personalized brain stimulation for emerging therapies. (Source: Nextgov.com)

Company Raises $110 Million in Series D Financing, Plans to Trade Publicly, and Enters a Collaboration Regarding Potential Neuromodulation Treatment in Heart Patients

July 5, 2022 - Orchestra Biomed announced a strategic collaboration with Medtronic and a plan to become a publicly traded company, in addition to finalizing a Series D round of financing for $110 million. In the strategic collaboration, the company will further develop its BackBeat Cardiac Neuromodulation Therapy as a potential treatment for hypertension in patients indicated for a cardiac pacemaker. In the plans to trade publicly on Nasdaq, the company said it will enter a definitive business combination agreement with the special purpose acquisition company HSAC2. The deal would provide a minimum of $70 million at closing, and potentially up to $160 million if no HSAC shareholders redeem shares. (Source: Mass Device)

Authors Summarize Studies about Electrical Stimulation in Cerebral Vasospasm

July 4, 2022 - A review summarized studies of electrical stimulation as a potential therapy or preventive option for cerebral vasospasm, a complication of subarachnoid hemorrhage. (Source: NeuroNews)

Studies Report Outcomes of Spinal Cord Stimulation for Chronic Back Pain without Prior Surgery

July 1, 2022 - A systemic review gathered evidence regarding outcomes for spinal cord stimulation in chronic back pain patients who had no prior back surgery. (Source: Neuromodulation: Technology at the Neural Interface)

Study Investigates Observations about Bimodal Stimulation in Tinnitus

June 30, 2022 - A randomized trial followed 191 tinnitus patients for 12 months to investigate effects of different bimodal neuromodulation settings that combine sound and electrical stimulation of somatosensory pathways. (Source: Scientific Reports)

Authors Summarize Network Mechanisms Underlying Neurostimulation for Epilepsy

June 30, 2022 - An open-access review discusses treatment of epilepsy with deep brain stimulation or responsive neurostimulation based on current and emerging targets within the brain's epileptogenic network, with the the potential to guide that selection through network analyses. (Source: Brain)

NHS Clinic Team Receives Recognition for Working to Establish a Brain-Stimulation Treatment Service for Patients with Depression

June 30, 2022 - A clinic team worked for two years to establish a permanent service for repetitive transcranial magnetic stimulation for people with treatment-resistant depression in Whiteleaf, U.K. and has now received an NHS service team award for their efforts. (Source: Oxford Health NHS Foundation Trust)

Authors Review Deep Brain Stimulation Studies in Huntington's Disease

June 29, 2022 - Clinicians published an update that summarized published reports about two investigational therapies for patients with treatment-resistant Huntington's disease; deep brain stimulation to the globus pallidus internus/externus, or intracranial brain-graft injection. (Source: Expert Review of Neurotherapeutics)

Company Points to Preclinical Evidence for Investigational Functional Electrical Stimulation Technique

June 30, 2022 - Onward Medical N.V. announced that publication of a study in non-human primates shows potential for the company's implantable investigational neurostimulation system to help restore hand and arm motion in people with spinal cord injury. (Source: Business Wire)

New Reimbursement Codes Anticipated in U.S. for Noninvasive Neurostimulation Method for Chronic Pain

June 29, 2022 - NeuraLace Medical announced new reimbursement codes will come into effect in January 2023 in the U.S. for its noninvasive neurostimulation device for chronic neuropathic pain. (Source: PR Newswire)

Journal Article Presents Results Concerning Neurostimulation Therapy for Acute Migraine

June 24, 2022 - Results were published in a randomized controlled trial of combined occipital and trigeminal neurostimulation in acute treatment of migraine. (Source: Headache Journal)

Article Reviews the State of Directional Deep Brain Stimulation to Treat Parkinson's Disease

June 8, 2022 - Two co-authors present an overview of directional deep brain stimulation (DBS) in Parkinson's disease, summarizing current status and published evidence concerning the various directional DBS leads that are commercially available. The predict that eventually, adaptive systems will be developed to provide a more predictive way to apply the therapy. (Source: touchNeurology)

Enrollment Begins in Clinical Trial of Neurostimulation System for Neurogenic Bladder

June 28, 2022 - SpineX announced enrollment of the first patient in its pivotal trial of a noninvasive neuromodulation device for the treatment of neurogenic bladder. (Source: Mass Device)

Retrospective Study Assesses Salvaging Relief in Chronic Pain Patients Who Tried Spinal Cord Stimulation

June 24, 2022 - Results appear in an open-access article in press concerning a multicenter retrospective review of 60 chronic pain patients who were trialed for dorsal root ganglion stimulation, from 2016 to 2020, to salvage pain relief after failed trials of traditional spinal cord stimulation, or loss of efficacy. (Source: Neuromodulation: Technology at the Neural Interface)

Researchers Investigate Neural Devices to Provide Sensory Input for Paralyzed Patients

June 24, 2022 - A video news magazine segment presents research into providing a sense of touch to paralyzed people who use brain-machine interfaces to regain some hand and arm function. (Source: Wall Street Journal)

Researchers Study a Neural Interface for Control of Robotic Arms

June 28, 2022 - An article describes research in which a man with partial arm paralysis was fitted with a brain-machine interface meant to permit control of robotic arms. (Source: Tech Times)

Brain-Computer Interface Company Announces a Cumulative Milestone in Days of Implantable Device Research

June 28, 2022 - The company Blackrock Neurotech announced its implantable brain-computer interface technology has undergone a total of 30,000 days of in-patient research. (Source: PR Newswire)

Case Presented of Spinal Cord Stimulation in Cancer-Related Pain

June 27, 2022 - A clinical vignette poster presented the case of a patient who was treated for cancer-related pain with spinal cord stimulation, after other methods were not sufficient. (Source: Pain Medicine News)

Noninvasive Neurostimulation Studied in Patients with Prolonged COVID-Related Smell Loss

June 24, 2022 - Results of a small, double-blind, sham-controlled study were published about seven patients with loss of smell for at least six months following COVID-19 infection, received anodal transcranial direct current stimulation combined with olafactory training. (Source: Medscape)

Company Announces Cortical Stimulation Patent Granted in Japan

June 23, 2022 - The company neurocare group AG announced it has obtained a patent in Japan for a method to guide cortical stimulation to a focal site, such as transcranial magnetic stimulation for depression, according to the company's announcement. (Source: Globe Newswire)

Study Investigates Side Effect in Parkinson's Disease Patients Treated with Deep Brain Stimulation

June 23, 2022 - An article summarizes a prospective study of 111 patients with Parkinson's disease who received deep brain stimulation to the subthalamic nucleus and were followed for a year. In the 18 who developed mania, factors associated with its development and management were analyzed. (Source: Parkinson's News Today)

Presentation Addresses Research into Neuromodulation Approaches to Long COVID

June 22, 2022 - An article summarizes research into potential neuromodulation treatments for "long COVID", which were subject to a presentation at the International Neuromodulation Society 15th World Congress. (Source: NeuroNews)

Presentation Addresses Research into Neuromodulation Approaches to Long COVID

June 22, 2022 - An article summarizes research into potential neuromodulation treatments for "long COVID", which were subject to a presentation at the International Neuromodulation Society 15th World Congress. (Source: NeuroNews)

Company Receives Permission for a U.S. Feasibility Trial of a Fully Implanted Cochlear Implant

June 22, 2022 - The company Envoy Medical announced it received investigational device exemption from the FDA for an early feasibility study of its fully implanted cochlear implant, which processes sound vibrations entering the ear and has no microphone. (Source: Medical Device Network)

Review Considers the Role of a Spinal Cord Stimulator Trial Phase

2022 - A review examines the question of the trial phase traditionally used before permanent implantation of a spinal cord stimulator. (Source: The Internet Journal of Neurosurgery)

Research Groups to Collaborate on Home-Based Research into Brain-Computer Interfaces

June 21, 2022 - Blackrock Neurotech and the University of Pittsburgh's Rehab Neural Engineering Labs announced a partnership which they say could enable more people with brain computer interfaces to participate in at-home studies using portable systems. (Source: PR Newswire)

Protocol Published for a Pilot Controlled Trial of Pink Noise Cortical Stimulation in Patients with Chronic Low Back Pain

June 15, 2022 - Researchers in New Zealand and Ireland published a protocol for a pilot, safety and feasibility randomised placebo-controlled trial of a novel neuromodulation method in chronic low back pain, high-definition transcranial infraslow pink noise stimulation (HD-tIPNS). The pilot study of 40 participants would be triple-blinded with the active arm of HD-tIPNS targeting the somatosensory cortex and dorsal and pregenual anterior cingulate cortex. (Source: BMJ Open)

Vagus Nerve Stimulation Device Company Raises $53 Million

June 20, 2022 - MicroTransponder, Inc. closed a series E round of funding for $53 million. The company plans to use the funds to commercialize its vagal nerve stimulation system for rehabilitation of hand and arm motion in stroke survivors. (Source: WBRC)

Guide: Neurostimulation for Refractory Chronic Mechanical Low Back Pain

June 20, 2022 - A team of co-authors has published a clinical guide for therapy adoption of restorative neurostimulation in refractory chronic mechanical low back pain. (Source: Journal of Pain Research)

Review: Recent Advances in Focused Ultrasound for Epilepsy

June 20, 2022 - An article discusses focused ultrasound as an investigative treatment alternative for drug-resistant epilepsy, which at low intensity can modulate neuronal activity. (Source: Frontiers in Neuroscience)

News Segment Features an Essential Tremor Patient Whose Neurostimulator is Remotely Adjusted Through Telemedicine

June 20, 2022 - A woman with essential tremor in rural Nebraska is using telemedicine to adjust settings on her deep brain stimulator, rather than driving eight or nine hours to Colorado, where her surgery was done. (Source: KETV)

Study is Investigating Deep Brain Stimulation in Pediatric Patients with Treatment-Refractory, Self-Injurious Behavior

June 19, 2022 - A girl with a rare neurological disorder, Pitt-Hopkins syndrome, entered a clinical study https://clinicaltrials.gov/ct2/show/NCT03982888 of deep brain stimulation to the nucleus accumbens  in children with autism spectrum disorder and treatment-refractory, repetitive self-injurious behavior. (Source: CTV)

Late-Breaking Research Presented from Clinical Trial of Deep Brain Stimulation in Huntington's Disease

June 17, 2022 - A late-breaking research presentation at the International Neuromodulation Society 15th World Congress summarized results of a randomized controlled clinical trial of pallidal deep brain stimulation in chorea-dominant Huntington's disease. (Source: NeuroNews)

Company Agrees to Sell Assets for $40 Million

June 15, 2022 - Stimwave Technologies Incorporated and its subsidiary Stimwave LLC announced filing for Chapter 11 bankruptcy in the United States. The company said it has agreed to sell substantially all its assets to Kennedy Lewis Management LP or its affiliate $40 million. Other qualified prospective bidders may participate in an auction process as part of the court-supervised bankruptcy proceeding. (Source: WDRB.com)

Presentation Covers Occipital Nerve Stimulation in Chronic Cluster Headache

June 15, 2022 - At the International Neuromodulation Society 15th World Congress, data were presented from a mulitcenter randomized controlled trial of occipital nerve stimulation in medically intractable chronic cluster headache. (Source: NeuroNews)

Article Recounts Highlights of the INS 15th World Congress

June 7, 2022 - In an interview, International Neuromodulation Society President Marc Russo, MBBS DA (UK) FANZCA FFPMANZCA, summarized highlights of the INS 15th World Congress, which featured research presentations, technical advances, mentorship receptions, and interest from the global neuromodulation community. He also mentioned upcoming INS regional meetings in the Southern and Northern hemispheres, respectively, in November 2022 and in 2023. (Source: touchNeurology)

Pilot Study Will Evaluate Deep Brain Stimulation in Refractory Opioid Use Disorder

June 14, 2022 - Clinicians in Pennsylvania announced the start of a pilot study of deep brain stimulation to treat up to three patients who have refractory opioid use disorder. (Source: PR Web)

Study Elucidated Potential Brain Circuit Targets Involved in Addiction

June 13, 2022 - Researchers reported in Nature Medicine that potential brain targets for neuromodulation to treat addiction have been identified through lesion mapping. (Source: Revyuh)

Presentation Focuses on Noninvasive Vagus Nerve Stimulation in Postpartum Depression

June 13, 2022 - A pilot study of auricular vagus nerve stimulation in women with postpartum depression was presented  at the American Society of Clinical Psychopharmacology annual meeting .(Source: Legal Reader)

Company Initiates Patient Access Program

June 1, 2022 - Helius Medical Technologies, Inc. announced it has launched a patient therapy access program in the United States for to assist multiple sclerosis patients with access to its noninvasive neurostimulator. (Source: KULR8)

Company Announces FDA Clearance for Parkinson's Disease Symptom Tracker Associated with Neuromodulation Therapy

June 13, 2022 - Rune Labs announced FDA clearance for software that provides monitoring of Parkinson's disease symptoms through a wearable device, an Apple watch. Their product is subject to a collaboration with Medtronic to integrate deep brain stimulation data. (Source: PR Newswire)

Report: Pain Patients Maintained Spinal Cord Stimulation Treatment During Pregnancy

June 10, 2022 - A small study reports on several women who had had active burst-mode spinal cord stimulation during pregnancy. (Source: Neuromodulation: Technology at the Neural Interface)

Segment Features Early Participant in Clinical Trial of Brain Stimulation Implant in Alzheimer's Disease

June 10, 2022 - A news report describes a patient's results from 24 months of deep brain stimulation targeting the fornix in a clinical trial in patients with Alzheimer's disease. (Source: Channel 5 NBCDFW)

Data Presented Concerning Neurostimulation in Painful Diabetic Neuropathy

June 10, 2022 - Data from 24 months of 10kHz spinal cord stimulation in painful diabetic neuropathy were reported at scientific sessions of the American Diabetes Association. (Source: NeuroNews)

Company Announces Completion of Primary Endpoints in Ongoing Neurostimulation Study

June 6, 2022 - Neuros Medical announced completion of 90-day primary endpoints in its QUEST pivotal trial of peripheral nerve stimulation in post-amputation pain. (Source: PR Newswire)

Clinical Trial Design Reported for Sham-Controlled Study of Peripheral Nerve Stimulation for Chronic Pain Condition

June 3, 2022 - A journal article reports a clinical trial design that includes an active sham control in a study of peripheral nerve stimulation for post-amputation pain. (Source: Journal of Pain Research)

Study Focuses on Noninvasive Brain Neurostimulation in Migraine

May 3, 2022 - Data were reported from a prospective, randomized, controlled clinical trial of combined external occipital and trigeminal neurostimulation for migraine headache. (Source: Pain and Therapy)

Neurostimulator Company Announces Startup Award

June 8, 2022 - PathMaker Neurosystems Inc. announced it has received a $100,000 MassVentures START award which it plans to use in preparing to commercialize a noninvasive neuromodulation device to treat spasticity. (Source: Globe Newswire)

Article Recaps INS Preconference on Neuromodulation Innovation

June 7, 2022 - An article recaps the International Neuromodulation Society 15th World Congress "Innovations Day" preconference, which featured presentations by startups and panel discussions on commercialization topics. (Source: Neurotech Reports)

Editorial Considers Emerging Neuromodulation Technologies

June 7, 2022 - An editorial discusses emerging neuromodulation tecniques and outlooks, including a recently announced approach of using "subwave" stimulation of dorsal horn dendrites in chronic pain. (Source: Neurotech Reports)

Company Names Chief Medical Officer for Neuromodulation Unit

June 7, 2022 - Medtronic announced its new neuromodulation operation unit chief medical officer will be Dr. Ashwini Sharan. (Source: Mass Device)

Company Announces First Commercial Implantation of Its Neurostimulator for Overactive Bladder

June 6, 2022 - Valencia Technologies Corporation announced the first commercial implantation of its tibial nerve stimulator for the treatment of urinary urge incontinence. (Source: PR Newswire)

Company Seeks FDA Approval for a Sacral Neuromodulation System

June 4, 2022 - Axonics filed a premarket approval supplement with the FDA for its fourth-generation implantable sacral nerve stimulator for the treatment of bladder and bowel dysfunction. (Source: NeuroNews)

Company Enters Collaboration on Neurostimulation for Reduction of Bleeding

June 2, 2022 - Spark Biomedical announced a collaboration with The Feinstein Institutes for Medical Research at Northwell Health to commercialize the company's wearable transcutaneous auricular neurostimulation device to slow blood loss in surgery, during response to traumatic accidents, or prophylatically for combat. (Source: Yahoo! Finance)

"Subwave" Stimulation Approach to Spinal Cord Stimulation Presented

May 31, 2022 - A plenary lecture at the International Neuromodulation Society's 15th World Congress detailed six-month results in 26 chronic pain patients of a novel spinal cord stimulation approach that targets dorsal horn dendrites. (Source: NeuroNews)

Company Announces Clearance for Neurostimulator for Dry Eye Disease

May 31, 2022 - Olympic Ophthalmics announced FDA clearance of its second-generation neuromodulation device that is intended to increase tear production in dry eye disease. (Source: Healio)

Researchers Study Pain Patients' Function and Quality of Life after Neurostimulation Treatment

May 26, 2022 - A study investigates the association between functional disability and health-related quality of life, estimating utility values after treatment with evoked compound action potential spinal cord stimulation for chronic pain. (Source: Neuromodulation: Technology at the Neural Interface)

Presentation Summarizes Recent Studies and Reviews about Spinal Cord Stimulation

May 23, 2022 - An article, in Spanish, describes presentation of recent studies and systematic reviews about spinal cord stimulation for chronic pain, which took place during a public educational event in Barcelona prior to the International Neuromodulation Society 15th World Congress. (Source: La Vanguardia)

External Neurostimulator Cleared in U.S. for Fibromyalgia Patients with High Pain Sensitivity

May 22, 2022 - The U.S. FDA has cleared the Quell external neuromodulation device for reducing the symptoms of fibromyalgia in adults with high pain sensitivity. (Source: Medical Dialogues)

Article Featuring Cluster Headache Includes Neuromodulation Options

May 22, 2022 - An article about cluster headaches includes both occipital nerve and deep brain stimulation when describing treatment options. (Source: El Pais)

Company Plans U.S. Study of Spinal Cord Stimulator

May 21, 2022 - Micro-Leads Inc. has received approval from the FDA to begin a study of its spinal cord stimulation system for chronic pain. (Source: Globe Newswire)

Six-Month Results Presented in Study of Spinal Cord Stimulation Targeting Non-Dorsal Column, Non-Axonal Structures

May 23, 2022 - Six-month results were presented at the International Neuromodulation Society 15th World Congress from a study into spinal cord stimulation in chronic pain patients that targets non-dorsal column, non-axonal structures. (Source: touchNeurology)

Company Highlights Closed-Loop Technology Presentations

May 18, 2022 - Saluda Medical announced scientific presentations at the International Neuromodulation Society 15th World Congress concerning its closed-loop spinal cord stimulation system. (Source: PR Newswire)

Noninvasive Brain Stimulation Pivotal Trial Planned

May 18, 2022 - Flow Neuroscience announced it will launch a U.S. pivotal trial of its transcranial direct current stimulation headset in the treatment of major depressive disorder. (Source: NeuroNews)

Results Reported in tDCS Trial in COVID Patients with Respiratory Distress

May 1, 2022 - A sham-controlled trial evaluated effects of active high-definition transcranial direct current stimulation plus respiratory rehabilitation on moderate-to-severe acute respiratory distress syndrome in patients with COVID-19, who received the treatment for up to 10 days in the intensive care unit. (Source: Brain Stimulation Journal)

18-Month Data Presented from Patients Who Received Neurostimulation Treatment for Painful Diabetic Neuropathy

May 14, 2022 - Data from 18 months of treatment were presented at the AACE Annual Scientific and Clinical Conference regarding patients who received spinal cord stimulation for painful diabetic neuropathy. (Source: Healio)

Survey: Providers' Goals for Neuromodulation Therapy for Chronic Pain

May 10, 2022 - A three-part survey of 88 healthcare providers at the 2nd Joint Congress of the International Neuromodulation Society European Chapters in 2021 asked clinicians: their goals for treating pain pains with neuromodulation, factors expected to change, and definition of success; for instance, increased mobility or quality of life. (Source: Neuromodulation: Technology at the Neural Interface)

Noninvasive Brain Stimulation System Receives FDA Clearance for OCD

May 10, 2022 - Neuronetics, Inc. announced its transcranial magnetic stimulation system received FDA approval as an adjunct treatment for adults with obsessive compulsive disorder. (Source: Globe Newswire)

Heart-Failure Neurostimulation Device Receives MRI-Conditional Labeling from the FDA

May 9, 2022 - CVRx, Inc. announced it received FDA approval for magnetic resonance-conditional labeling of its Barostim system for treatment of heart failure (in Europe, the system is also CE marked for resistant hypertension). (Source: Globe Newswire)

Company Raises $64 Million in Financing

May 9, 2022 - BlueWind Medical, Ltd., announced it has closed a series B funding round of $64 million and plans to file later this year for FDA marketing clearance of its implantable tibial neuromodulation device for overactive bladder. (Source: PR Newswire)

Video Podcast Previews INS 15th World Congress

May 9, 2022 - In a 4-minute overview video, International Neuromodulation Society President A/Prof. Marc Russo previews the upcoming INS 15th World Congress, which will have simultaneous streams on pain, brain, and organ stimulation. He said the meeting will offer research, reviews, techniques, and information about startups and medical-device ventures, as well as opportunities for mentoring and interaction with international colleagues. (Source: touchNeurology)

Article: Novel Deep Brain Stimulation Targets for Movement Disorder

May 5, 2022 - A summary presents novel deep brain stimulation targets for movement disorder, as described in a recent journal article. (Source: DocWire News)

Article Covers Vagus Nerve Stimulation for Depression

May 5, 2022 - An article summarizes a recent overview of vagus nerve stimulation as a treatment for therapy-resistant depression. (Source: Medscape)

Outcome-Survey Results Published Regarding Temporary Neurostimulation for Pain

May 4, 2022 - Results were published from patients surveyed between 3 and 30 months after they had received 60 days of peripheral nerve stimulation for pain. (Source: Future Medicine)

Clinical Trial of Neurostimulation for Adolescents with Epilepsy Enrolls First Patient

May 4, 2022 - NeuroPace, Inc. announced the first patient was enrolled in a clinical trial of its responsive neurostimulation system in adolescents with drug-resistant focal epilepsy. (Source: BioSpace)

Company's Brain-Cumputer Interface Clinical Trial Enrolls First U.S. Patient

May 4, 2022 - Synchron Inc. has enrolled its first U.S. patient in a clinical trial of its Stentrode, an endovascular brain-computer interface. (Source: Bloomberg News)

Innovators Describe Neurostimulation Approach to Treat Foot Drop

April 30, 2022 - An article describes a lower-extremity functional electrical stimulation system that uses dual stimulation to address foot drop. (Source: Neurotech Reports)

Article Describes Neurostimulator Lead Placement Technique

April 15, 2022 - A team of physicians has published a technique for S1 dorsal root ganglion stimulation lead placement. (Source: Pain Medicine)

Retrospective Study Examines Perceived Pain Reduction from Different Frequencies of Spinal Cord Stimulation

April 28, 2022 - A retrospective study of 237 pain patients treated from 2004 to 2020 assessed perceived pain reduction, comparing results between males and females who received spinal cord stimulation at either high or low frequency. (Source: Science Daily)

Machine-Learning Models in Development for Selection of Candidates for Spinal Cord Stimulation

April 28, 2022 - Using a prospectively collected database, researchers are developing predictive models regarding which patients might be anticipated to benefit from spinal cord stimulation for chronic pain. (Source: Florida Atlantic University)

Analysis: Noninvasive Brain Stimulation and Smoking Cessation

April 28, 2022 - Researchers published a systemic review and meta-analysis of noninvasive brain stimulation in smoking cessation programs. (Source: News.am)

Patients in the U.K. Undergo Clinical Trial with a Skull-Implanted Neurostimulator for Parkinson's Disease

April 27, 2022 - An article describes some of the first clinical experience with an investigational neurostimulation device implanted into the skull as a potential treatment for the motor effects of Parkinson's disease. (Source: Mirror)

Company Launches Neurostimulation Trial Digital Health App Upgrade

April 28, 2022 -- Abbott announced release of an upgraded digital health app for tracking patients undergoing a neurostimulation trial for chronic pain. (Source: PR Newswire)

Company Announces Peripheral Nerve Stimulation Trial for Chronic Knee Pain

April 22, 2022 - Stimwave Technologies announced the launch of a series of clinical trials, starting with a trial that monitors its peripheral nerve stimulation system in patients with chronic knee pain. (Source: NeuroNews)

Company Announces Noninvasive Vagus Nerve Stimulation Study in Heart Patients

April 21, 2022 - Parasym Ltd. issued a press release about a study published in January of its noninvasive vagus nerve stimulation system in patients with heart failure with preserved ejection fraction. (Source: Yahoo! Finance)

Paper Summarizes Survey Results of Primary-Care Residents' Knowledge of Neuromodulation for Back Pain in Rural Clinics

April 21, 2022 - Researchers at the University of Arkansas surveyed rural family medicine residents for familiarity with neuromodulation as a treatment for post-laminectomy syndrome. (Source: Journal of Pain Research)

Review Analyzes Findings in Noninvasive Brain Stimulation in Patients with OCD

April 21, 2022 - A news article recounts publication in Psychiatry Research of a systemic review and meta-analysis about repetitive transcranial magnetic stimulation in the treatment of obsessive compulsive disorder. (Source: Dermatology Advisor)

Narrative Review Focuses on Patient Selection for Spinal Cord Stimulation

April 20, 2022 - A group of international authors prepared a narrative review that presents a sequential decision-making model for patient selection for spinal cord stimulation in the treatment of chronic pain. (Source: Journal of Pain Research)

Company Announces Further Study of Its Neurostimulator

April 19, 2022 - According to a company announcement, a U.S. Air Force program plans to further research the electroCore, Inc.'s noninvasive vagus nerve stimulation device to potentially enhance training performance in the environment of intelligence, surveillance and reconnaissance. (Source: Street Insider)

Device Company Launches Its Sacral Neuromodulation System in the United States

April 19, 2022 - Axonics announced a comprehensive U.S. launch of its sacral neuromodulation system that received FDA approval in March. (Source: NeuroNews)

Device Company Announces Issuance of New Patents

April 19, 2022 - NeuraLace Medical, Inc. announced issuance of two U.S. patents related to its technology for the treatment of peripheral nerve pain. (Source: PR Newswire)

INS 15th World Congress Innovations Day Preconference Program Announced

April 15, 2022 - The International Neuromodulation Society is holding its sixth World Congress preconference for the global neuromodulation innovation and investment community, "Neuromodulation without Borders," on May 22, 2022 in Barcelona. The event features presentations by emerging companies, entrepreneurs, medical device industry representatives and members of the investment community. (Source: INS)

Company Receives FDA Approval for Deep Brain Stimulation Software

April 12, 2022 - Boston Scientific Corporation has received FDA approval for guided programming software, STIMVIEW XT, used in conjunction with its Vercise Genus deep brain stimulation system. (Source: Neurology Live)

Column Describes Emerging Directions of Neural Interface Therapies

April 12, 2022 - A column surveys investment and development of brain-stimulation or bioelectronic medicine therapies, citing examples of investigational approaches and emerging companies. (Source: Octopus Ventures)

Study Protocol Published for Brain Stimulation-Assisted Cognitive Training Post-COVID

April 11, 2022 - Investigators published a phase IIb trial study protocol for studying brain stimulation-assisted cognitive training in patients with post-COVID-19 cognitive impairment. (Source: BMJ Open)

Case Published of Spinal Cord Stimulation in a Patient with Orthostatic Hypotension

April 6, 2022 - Clinicians reported a case of a woman with orthostatic hypotension who frequently fainted, describing use of a spinal cord stimulator that targets nerves that constrict arteries in the legs and trunk when activated. (Source: Live Science)

Company Announces a Reimbursement Decision in Germany

April 5, 2022 - Stimwave Technologies announced the German Institute for Hospital Remuneration granted two of the company's neurostimulator products a stauts that provides a pathway for potential additional hospital reimbursement. (Source: Business Wire)

Clinicians Report Results of Study of Vagus Nerve Stimulation in Hospitalized COVID Patients

April 8, 2022 - Results were published from the SAVIOR I randomized controlled trial of noninvasive vagus nerve stimulation to treat respiratory symptoms and inflammation biomarkers  in patients hospitalized with COVID-19. (Source: Frontiers in Neurology)

Research Into Transcranial Magnetic Stimulation Explores Targeting with Brain Imaging for Depression Treatment

April 7, 2022 - An article describes theta burst transcranial magnetic stimulation in depression and individual tailoring of the location using functional magnetic resonance imaging (fMRI). Another article describes using fMRI and diffusion tensor imaging to target deeper areas of the brain. (Source: Discover Magazine

Company Announces Results of Neurostimulation Study in Acute Migraine

April 6, 2022 - Cefaly Technology announced results of a Phase 3 clinical trial of external trigeminal nerve stimulation for acute treatment of migraine attacks. (Source: Medical Dialogues)

Presentation Covers Findings in Noninvasive Nerve Stimulation After Stroke

April 6, 2022 - Data about safety and feasability were presented in a sham-controlled study of noninvasive vagus nerve stimulation administered up to six hours after stroke. (Source: Neurology Live)

Company Announces a Certification for Its Latest Spinal Cord Stimulation Platform

April 5, 2022 - Stem-Tronics.com announced certification for a next-generation implanted neurostimulator for pain management. (Source: EINPresswire)

Collaboration Centers on Potential Intervention for Withdrawal Symptoms in Opioid Use Disorder

April 5, 2022 - Battelle and Spark Biomedical, Inc. announced they will collaborate on a pilot study to remotely detect biomarkers of withdrawal from opioid use disorder, as a preliminary step toward developing a closed-loop neurostimulation approach to opioid withdrawal. (Source: Business Wire)

Analysis Assesses Uptake of Spinal Cord Stimulation in England

April 5, 2022 - A statistical analysis from 2010 - 2020 assessed the uptake of spinal cord stimulation across the National Health Service in England. The therapy has been recommended there as a management option for chronic neuropathic pain since 2008. (Source: Neuromodulation: Technology at the Neural Interface)

Pre-Commercial Brain-Stimulation Spinout Announces Funding

April 5, 2022  - A Swiss spinout that is developing an implantable brain-stimulation device, Neurosoft Bioelectronics Ltd., announced it has received funding of nearly $3 million, from the SERI-Funded European Innovation Council Accelerator Grant and a share of the $165,000 USD through the European Research Council Proof-of-Concept Grant, as well as a $100,000 convertible note. The company is pursuing an initial application in epilepsy. (Source: Send2Press)

Brain-Computer-Interface Startup Raises $10 Million in Seed Funding

March 30, 2022 - Inner Cosmos Inc. announced it raised $10.25 million in seed funding as it plans to pursue a brain-computer interface to potentially treat depression. (Source: Bloomberg)

Company Receives FDA Clearance for Tear-Production Device

March 31, 2022 - Olympic Ophthalmics announced it has received clearance from the FDA for a tear-production neuromodulation device, and has three ongoing clinical trials. (Source Medical Device Network)

In Preclinical Work, Collaborators Demonstrate a Proof-of-Concept Peripheral Nerve Stimulator

March 31, 2022 - A team of co-authors in Texas published a proof-of-concept demonstration of an endovascular peripheral nerve stimulator. (Source: EurekAlert)

Analysis of Cortical Signals Shows Areas of Grasp and Speech Encoding

March 31, 2022 - In a person with tetraplegia, researchers decoded signals for grasping and speech from a cortical circuit they say might be considered for a target for a brain-computer interface. (Source: Neuron)

Researchers Use Neuromodulation Data from Dystonia Patients to Model Electrode Placement and Investigate Stimulation Effects

March 31, 2022 - A paper presents deep brain stimulation effects in 80 patients with either cervical or generalized dystonia, retrospectively investigates tracts associated with improvements, and maps optimal stimulation sites. (Source: PNAS)

Retrospective Analysis Reports Procedure-Related Outcomes for Spinal Cord Stimulation

April 2022 - In a retrospective analysis of procedure-related outcomes, physicians evaluated a readmission database for 3,737 patients who received spinal cord implantation between 2013 and 2017. (Source: Anesthesia & Analgesia)

Brain-Computer Interface Study Results to Be Presented, Further Clinical Study Planned

March 30, 2022 - Results will be presented at an upcoming meeting of an Australian study in which four people with quadriplegia had a brain-computer interface threaded into a vein near the motor cortex. An ensuing clinical study in Pittsburgh, PA will map sensorimotor activity. (Source: Pittsburgh Post-Gazette)

Patients Implanted in a Tibial Nerve Stimulation Pivotal Trial for Overactive Bladder

March 25, 2022 - Medtronic announced it completed the first implants in a pivotal trial of its investigational tibial nerve stimulation device in patients with overactive bladder. (Source: Mass Device)

Researchers Study Noninvasive Brain Stimulation in Stroke Recovery

March 25, 2022 - A study by researchers in Germany assessed transcranial direct current stimulation in augmenting motor recovery following stroke, whose physical rehabilitation involved using virtual tasks performed via a personalized robotic system. (Source: Medical Xpress)

Study Analyzes Comparative Treatment Costs, With or Without Vagus Nerve Stimulation, in Children with Drug-Resistant Epilepsy

March 25, 2022 - In a study that drew on data from 44 children's hospitals in the U.S., researchers analyzed comparative treatment costs for children with drug-resistant epilepsy who were treated either with anti-seizure medication alone (n=3471), or with anti-seizure medication and vagus nerve stimulation (n=1113). (Source: Science Daily)

Results Presented in Randomized Trial of Spinal Cord Stimulation

March 24, 2022 - Data from a clinical trial of high-frequency spinal cord stimulation were presented at the 2022 annual meeting of the North American Neuromodulation Society. (Source: NeuroNews)

Researchers Start Study of Noninvasive Brain Stimulation in Alzheimer's Disease

March 23, 2022 - Researchers at the Medical University of South Carolina are beginning a study of the effects of transcranial magnetic stimulation in the progression of Alzheimer's disease. (Source: WCSC)

Observations Published of Vagus Nerve Stimulation Effects on Autistic Behaviors

March 21, 2022 - An observational study in pediatric patients who were being treated with vagus nerve stimulation for drug-resistant epilepsy reported the treatment effects on autistic behaviors. (Source: DocWire News)

Data Presented from Randomized Trial of Dorsal Root Ganglion Stimulation at Frequencies as Low as 20Hz

March 15, 2022 - A presentation at the 2022 annual meeting of the North American Neuromodulation Society covered a randomized study of dorsal root ganglion stimulation in chronic pain patients at frequencies from 20Hz to 80Hz. (Source: NeuroNews)

Physicians Study Spinal Cord Stimulation and Respiratory Function in Spine-Injury Patients

June 2022 - A research team assessed if high epidural spinal cord stimulation at a location related to intercostal muscles could facilitate respiratory function in two patients who were on mechanical stimulation due to spinal cord injury. (Source: Respiratory Physiology & Neurobiology)

Authors Report Response in Pain Patients During 60 Days of Percutaneous Peripheral Nerve Stimulation

March 14, 2022 - Based on data from several hundred patients who had up to two months of percutaneous peripheral nerve stimulation to various targets, an article postulates that length may help anticipate prospective longer-term responders. (Source: Journal of Pain Research)

Authors Report Response in Pain Patients During 60 Days of Percutaneous Peripheral Nerve Stimulation

March 14, 2022 - Based on data from several hundred patients who had up to two months of percutaneous peripheral nerve stimulation to various targets, an article postulates that length may help anticipate prospective longer-term responders. (Source: Journal of Pain Research)

Authors Report Response in Pain Patients During 60 Days of Percutaneous Peripheral Nerve Stimulation

March 14, 2022 - Based on data from several hundred patients who had up to two months of percutaneous peripheral nerve stimulation to various targets, an article postulates that length may help anticipate prospective longer-term responders. (Source: Journal of Pain Research)

Column Looks Ahead in the Field of Neuromodulation

March 9, 2022 - A column provides perspectives on the future of neuromodulation. (Source: NeuroNews)

Experts Discuss Tibial Nerve Stimulation Devices for Overactive Bladder

March 9, 2022 - Two clinicians discussed their experience and perspectives on tibial nerve stimulation devices for overactive bladder. (Source: Urology Times)

Study Looks at Minimally Invasive Nerve Stimulation in Sexual Dysfunction

March 8, 2022 - An interview discusses findings presented at a recent scientific meeting of a randomized controlled study of percutaneous tibial nerve stimulation in female sexual dysfunction. (Source: Urology Times)

Company Announces Its Stimulation Device Received FDA Clearance

March 8, 2022 - MyndTec announced FDA clearance for its electrical stimulation system for motor recovery following stroke or spinal cord injury. (Source: Yahoo! Life)

Company Receives FDA Clearance for Device to Address Foot Drop

March 8, 2022 - Cionic announced FDA Clearance for its Neural Sleeve, which delivers electrical stimulation to the legs of people with foot drop and muscle weakness. (Source: MobiHealthNews)

FDA Approval Announced for Spinal Cord Stimulation System

March 8, 2022 - Saluda Medical announced FDA approval for its closed-loop spinal cord stimulation system for the treatment of chronic intractable pain of the trunk and/or limbs. (Source: PR Newswire)

Company Announces FDA Approval of Sacral Neuromodulation System

March 7, 2022 - Axonics Modulation Technologies announced it received FDA approval for its new sacral neuromodulation system. (Source: Mass Device)

TV Segment Features Research Into an Injectable Electrode

March 7, 2022 - A television segment featured an injectable neurostimulation electrode, which the researchers reportedly hope to submit for FDA clearance over the next two years. (Source: 9and10news.com)

Company Begins Grant-Funded Clinical Trial in Post-Stroke Spasticity

March 7, 2022 - PathMaker Neurosystems, Inc. announced it has begun a U.S. multi-center clinical trial to evaluate its neurostimulation device in post-stroke upper-limb spasticity. The trial is funded by a $4.9M NINDS Cooperative Research to Enable and Advance Translational Enterprises for Devices (CREATE Devices) grant from the National Institute of Neurological Disorders and Stroke. (Source: Globe Newswire)

International Neuromodulation Society Announces Its 15th World Congress

March 7, 2022 - The International Neuromodulation Society issued a news release on the INS 15th World Congress to raise awareness of neuromodulation and to encourage attendance. (Source: EurekAlert)

Company Plans Phase II Trial of Noninvasive Neurostimulation for Neonatal Opioid Withdrawal Syndrome

March 3, 2022 - Spark Biomedical, Inc. has a $2.49 million grant from the National Institute of Health HEAL Initiative and plans a Phase II trial to evaluate its transcutaneous auricular nerve stimulation system as adjunctive therapy for neonatal opioid withdrawal syndrome. (Source: Yahoo! Finance)

Company Presents Wearable Brain Stimulation Device at Mobile Technology Meeting

March 3, 2022 - Neuroelectrics presented its noninvasive brain stimulation system at a mobile technology meeting last week in Barcelona. The company, which is based in Barcelona and Boston, is developing its wearable device to potentially help people living with seizures, sleep disorders, and autism. (Source: Interesting Engineering)

Noninvasive Brain Stimulation Studied in Cannabis Use Disorder

March 3, 2022 - Results were published of a study of transcranial magnetic stimulation in persons with schizophrenia who have cannabis use disorder. (Source: Science Daily)

Device Company Raises $125 Million in Equity Financing

March 2, 2022 - Saluda Medical announced completion of a $125 million round of equity financing, to support commercialization, research, and clinical development of the medical device company's neuromodulation portfolio. (Source: The Street)

FDA Approves Neurostimulator for Urinary Indication

March 2, 2022 - The FDA issued premarket approval for Valencia Technologies' eCoin leadless tibial neurostimulator to treat urinary urge incontinence. (Source: Urology Times)

Recruitment Underway in Study of Brain Stimulation for Obesity

March 2, 2022 - Pittsburgh-based Allegheny Health Network in Pennsylvania is recruiting six participants for a second phase of the clinical trial investigating deep brain stimulation of the hypothalamus in patients who have a body mass index above 50 with associated health risks, and who have not had sustainable results from gastrointestinal bypass surgery. (Source: Boston 25 News)

Review: Neuromodulation for Painful Diabetic Neuropathy

Feb. 28, 2022 - A review presents evidence on neuromodulation interventions for painful diabetic neuropathy. (Source: Current Pain and Headache Reports)

Parkinson's Patient Receives Deep Brain Stimulation Treatment for the First Time in Ireland

Feb. 27, 2022 - A newspaper article features the first Parkinson's disease patient to undergo deep brain stimulation in Ireland, rather than having to travel for the treatment. (Source: Independent.ie)

Company Announces First Investigational Implantation of Its Neurostimulation for Obstructive Sleep Apnea

Feb. 25, 2022 - LivaNova announced the first patient has been implanted in a clinical trial of its neurostimulator for obstructive sleep apnea. (Source Mass Device)

Company Plans to Market Brain-Computer Array in 2022

Feb. 23, 2022 - A news feature about research into converting thought into text via a brain-computer interface includes comments from an interview with the co-founder of Blackrock Neurotech, whose electrode array is expected to undergo commercialization this year. (Source: Forbes)

Researchers Present Retrospective Study Concerning Spinal Cord Stimulation

Feb. 25, 2022 - A meeting abstract in late 2021 presented single-institution data from 2004 - 2018 concerning length of benefit of spinal cord stimulation and impacts on opioid pain medication use. (Source: Pain Medicine News)

Study Planned of Vagus Nerve Stimulation for Prevention of Depression Relapse

Feb. 23, 2022 - A protocol was published for a longitudinal study of the effect and neural mechanisms of transcutaneous vagus nerve stimulation for relapse prevention in major depressive disorder. (Source: DocWire News)

Pilot Study Features Noninvasive Neurostimulation to Address Abnormal Heart Rhythm

Feb. 21, 2022 - A double-blind randomized pilot study published in JAMA Cardiology evaluated a single session of transcutaneous magnetic stimulation of the left stellate ganglion vs. sham in patients experiencing ventricular tachycardia. (Source: Medical Dialogues in Cardiology)

Review Focuses on Autonomic Neuromodulation and Atrial Fibrillation After Heart Surgery

Feb. 14, 2022 - A review article summarized findings of clinical studies of autonomic neuromodulation therapies and the risk that cardiac surgery patients may develop postoperative atrial fibrillation. (Source: BioSpace)

Neurostimulator Receives Breakthrough Designation

Feb. 22, 2022 - The Precisis AG's subcutaneous neurostimulator, Easee, has received breakthrough device designation from the FDA as a potential approach to prevent or mitigate seizures. (Source: BioSpace)

Findings Published from Bimodal Neuromodulation Study in Tinnitus

Feb. 21, 2022 - The company Neuromod Devices welcomed findings of an independent study in Germany of its bimodal neuromodulation device in participants with tinnitus. (Source: NeuroNews)

Brain-Stimulation Device Startup Joins Technology Incubator

Feb. 21, 2022 - Actipulse Neuroscience is joining the technology incubator Y Combinator. The startup is working on home-use noninvasive brain stimulation for depression or neurodegenerative conditions. (Source: Healthcare Tech Outlook)

Authors Publish Findings of Preliminary Brain Stimulation Study in Alzheimer's Disease

Feb. 9, 2022 - An international team of authors published a preliminary study of transcranial focused ultrasound to the hippocampus in Alzheimer's disease. (Source: Journal of Personalized Medicine)

Study Examines Spinal Cord Stimulation Disparities

April 2022 - Researchers published an analysis of a 2016-2018 U.S. inpatient sample that examined racial disparities in cost and utilization for patients receiving inpatient spinal cord stimulation for chronic pain. (Source: Journal of Clinical Neuroscience)

Australian Charity Advocates for Research into Neurostimulation for Spinal Cord Injuries

Feb. 22, 2022 - An actress from Australian television went on the air to discuss her husband's paralysis in support of a request by SpinalCure Australia to establish a national program for treatment and research into neurostimulation for spinal cord injuries. (Source: 7news.com.au)

Company's Sacral Neuromodulation Device Receives Approval in the U.S.

Feb. 22, 2022 - The FDA has approved a sacral neuromodulation device from Medtronic, the InterStim X. (Source: Mass Device)

Neurostimulator Company Raises $104 Million in Equity Financing

Feb. 18, 2022 - Device company Nalu Medical, Inc. closed a $104 million equity round of financing.(Source: FinSMEs)

Study Documents Effects of Neurostimulation in Patients Being Weaned from Mechanical Ventilation

Feb. 15, 2022 - In a randomized, controlled, open-label trial researchers reported on transient transvenous phrenic nerve stimulation in patients who were reliant on artificial ventilation and had diaphragm dysfunction; the authors documented the effect of the neurostimulation on both weaning from the ventilator and on maximal inspiratory pressure. (Source: Physician's Weekly)

Company Announces New Patent for Spinal Neuromodulation Device

Feb. 15, 2022 - Privately held SynerFuse, Inc. announced issuance of a U.S. patent concerning direct surgically open placement of a neuromodulation device over the dorsal root ganglion. Earlier, the company announced a patent that covers combined spinal fixation and neuromodulation to treat a spinal injury and chronic lower back pain. (Source: PR Newswire)

Study to Explore Noninvasive Brain Surgery Following Mild Traumatic Brain Injury in Veterans

Feb. 13, 2022 - A three-year, $4 million study funded by the U.S. Department of Defense will investigate transcranial direct current stimulation and transcranial magnetic stimulation in veterans who have had cognitive issues due to mild traumatic brain injury incurred within the last 20 years. (Source: Rio Rancho Observer)

Meta-Analysis Summarizes Studies of TENS for Pain

Feb. 10, 2022 - A team of authors published a systemic review and meta-analysis of studies concerning the efficacy and safety of transcutaneous electrical nerve stimulation for acute and chronic pain. (Source: BMJ Open)

Peer-Review Article Presents 12-Month Results in Spinal Cord Stimulation Clinical Trial

Feb. 11, 2022 - Clinicians published 12-month results of a randomized controlled trial of treatment of nonsurgical refractory back pain with 10 kHz spinal cord stimulation. (Source: Journal of Neurosurgery)

Authors Describe Development of Remote Device Programming Platform

Feb. 10, 2022 - A team of co-authors describe development of a remote-care platform for patients with an implanted neuromodulation device. (Source: Scientific Reports)

Segment Highlights Spinal Cord Stimulation Research for Post-Paralysis Rehabilitation

Feb. 10, 2022 - A television segment features a man with paraplegia who participated in a research study into spinal cord stimulation for recovery of some mobility, and his wedding to a caregiver on the 10-year anniversary of the accident that paralyzed him. (Source: WNDU)

FDA Schedules Medical Device Q&A Webinars for March

Jan. 25, 2022 - The U.S. FDA announced a March 1 webinar for members of industry and other stakeholders to address its final guidance, Principles for Selecting, Developing, Modifying and Adapting Patient-Reported Outcome Instruments for Use in Medical Device Evaluation. Also, the FDA will hold a March 22 webinar on its guidance, Patient Engagement in the Design and Conduct of Medical Device Clinical Studies. (Source: FDA Center for Devices and Radiological Health)

Feasibility Trial Involves Novel Brain Stimulation Device

Feb. 8, 2022 - A news feature describes a feasibility trial in the U.K. of a novel closed-loop implanted neurostimulator to target the pedunculopontine nucleus in patients with Parkinson's-like multiple systems atrophy. The research is aimed at identifying biomarkers of the disease state throughout the day and night and ultimately to develop stimulation patterns to manage symptoms and improve sleep. (Source: Medical Xpress)

Journal Article Summarizes Neuromodulation Treatments for Chronic Daily Headache

Feb. 7, 2022 - A team of co-authors in Italy reviewed the literature on the use of central and peripheral neuromodulation techniques for chronic daily headache. (Source: Current Pain and Headache Reports)

Article Reports Neurostimulation Treatment in Two Cases of Long COVID

Feb. 7, 2022 - In published findings concerning two patients who had symptoms of long COVID, authors report changes after administering alternating current stimulation of the eyes and brain each day for 10 - 13 days. (Source: Neuroscience News)

Clinicians Report on Spinal Cord Stimulation in a Case of Low Back Pain

Feb. 7, 2022 - A case report describes neurostimulation treatment in a patient who had chronic axial low back pain. (Source: Cureus)

Company Developing Noninvasive Brain Stimulation Files for an Initial Public Offering

Feb. 4, 2022 - Nexalin Technology has filed for an initial public offering, seeking to raise $10 million for development of its transcranial electrical stimulation technology, which the company is developing for treatment of mental health conditions like anxiety, insomnia and depression. (Source: New Business Herald)

Article Presents Clinical Results of Neurostimulation for Leg Movement Following Spinal Cord Injury

Feb. 7, 2022 - Researchers in Switzerland published results of a three-person study in Nature Medicine in which participants who had lost the ability to walk due to spinal cord injury received neurostimulation and training to recover voluntary movement in their legs. (Source: CNN Health)

ALS-Focused Philanthropy Provides $250,000 Prize for Neurostimulation Research

Feb. 7, 2022 - PathMaker Neurosystems, Inc. announced receipt of a $250,000 CERF Medical Electronics Prize from the Cullen Education and Research Fund, a London-based philanthropy focused on amyotrophic lateral sclerosis. The announcement said the funding may facilitate initiation of clinical studies. The award is being shared with the academic research laboratory of the company founder, where preclinical studies took place. (Source: Globe Newswire)

Visual Prosthesis Device Receives Breakthrough Device Designation

Feb. 1, 2022 - The FDA gave Breakthrough Device designation to a visual prosthesis by Bionic Vision Technologies, which is being developed for restoring partial vision. (Source: news.com.au)

Participants Sought for Clinical Trial of Deep Brain Stimulation in Alzheimer's Disease

Feb. 3, 2022 - A study site in Texas is recruiting patients with mild Alzheimer's disease for a clinical trial taking place at centers in the U.S., Canada, and Germany evaluating the potential of deep brain stimulation to slow or halt the condition. (Source: Yahoo! Finance)

Investigators Recruit Participants for Trial of Brain Stimulation in Alcohol Use Disorder

Feb. 3, 2022 - Researchers are seeking participants for a clinical trial in Albuquerque, N.M. of transcranial alternating current stimulation in alcohol use disorder. (Source: UNM)

Review Discusses Ultrasound Neuromodulation

Jan. 25, 2022 - A review, "Ultrasound as a Neurotherapeutic: A Circuit- and System-Based Interrogation," includes discussion of low-intensity focused ultrasound for brain mapping and neuromodulation. (Source: Focus)

Company Announces Insurer's Expanded Treatment Coverage

Feb. 3, 2022 - Abbott announced that the health insurer UnitedHealthcare has updated a medical policy that increases access to the device maker's dorsal root ganglion stimulation device for the treatment of chronic pain. (Source: Mass Device)

Investigators Report Data on Peripheral Nerve Stimulation Following Lower-Limb Amputation

Jan. 27, 2022 - Data from a pilot study were reported at a recent meeting concerning peripheral nerve stimulation for pain in the three months following lower-limb amputation. (Source: Pain Medicine News)

Enrollment Complete in Clinical Trial of Noninvasive Vagus Nerve Stimulation

Feb. 1, 2022 - The company electroCore announced enrollment was complete in its randomized, sham-controlled study of noninvasive vagus nerve stimulation to reduce the development of ileus following colorectal surgery. The 97-patient study is taking place at two centers in England and is sponsored by the UK National Institute for Health Research. (Source: Yahoo! Finance

Meta-Analysis Looks at Clinical Trials of Neurostimulation for Swallowing Disorder

Jan. 31, 2022 - Neurostimulation was included in a special journal issue on "Advances in Management of Voice and Swallowing Disorders," in which a review and meta-analysis summarized randomized controlled trials of pharygeal and neuromuscular electrical stimulation in people with swallowing issues due to oropharyngeal dysphagia. (Source: Journal of Clinical Medicine)

Article Presents Findings About Remote Followup in Sacral Neuromodulation Patients

Jan. 28, 2022 - A survey published in Neuromodulation: Technology at the Neural Interface examined patients' attitudes toward remote programming and virtual care in followup appointments after implantation of a sacral neuromodulation system. (Source: DocWire News)

Authors Present Contributions to Neurosurgery by Women in Neuromodulation

Jan. 20, 2022 - An article recounts innovative contributions by women in neuromodulation to the field of stereotactic and functional neurosurgery. (Source: Frontiers in Human Neuroscience)

Company Announces Implantation of Its Device in a Rheumatoid Arthritis Patient

Jan. 26, 2022 - Galvani Bioelectronics announced the first implantation of a patient with rheumatoid arthritis in a UK-based feasibility study of the company's technology for splenic nerve stimulation. In parallel, patient enrollment is open at several centers in a larger U.S.-based feasibility study of the same technology in the same condition.  (Source: Business Wire)

Article Profiles the New President of NANS

Jan. 25, 2022 - Incoming North American Neuromodulation Society (NANS) President Salim Hayek, MD, PhD, is profiled in the current issue of NeuroNews. (Source: NeuroNews)

Investigators Use Brain-Imaging Studies in Overactive Bladder Patients Receiving Sacral Neuromodulation

Jan. 24, 2022 - In a prospective study that compared healthy controls to patients who received sacral nerve stimulation for overactive bladder (including groups who either had success or failure), researchers in China observed changes in activation of the left dorsolateral prefrontal cortex through neuroimaging in the course of investigating a possible central mechanism for the disorder. (Source: The Journal of Urology)

Authors Publish Evidence of Long-Term Effects of Transcranial Pulse Stimulation

Jan. 15, 2022 - A research team in Austria has published a study in healthy volunteers comparing sham and verum sessions of transcranial pulse stimulation (TPS) that was focused on the coritcal somatosensory representation of the right hand. One week before and after the session, they tested tactile spatial discrimination and dexterity. (Source: Journal of Translational Medicine)

FDA Approval for Spinal Cord Stimulation Systems Includes an Indication of Painful Diabetic Neuropathy

Jan. 24, 2022 - Medtronic announced FDA approval of two neurostimulators for treating chronic pain, including that associated with diabetic peripheral neuropathy. (Source: Mass Device)

Company Highlights Clinical Results in Migraine Prevention Research

Jan. 24, 2022 - The company electroCore Inc. announced results of a randomized clinical trial published in Cephalalgia investigating its noninvasive vagus nerve stimulation device in migraine. (Source: Healio)

Foundation Announces Clinical Trials on Noninvasive Neurostimulation in Parkinson's Disease

Jan. 4, 2022 - The Michael J. Fox Foundation announced two ongoing clinical trials of neurostimulation devices in Parkinson's disease; "Use of a Non-Invasive Brainstem Neuromodulation Device to Improve Neurovascular Status in Parkinson's Disease" and "Vibrotactile Coordinated Reset: A Non-invasive Treatment for Parkinson's Disease". (Source: Michael J. Fox Foundation)

Event in Iran Features R&D Involving Brain Stimulation and Other Technologies

Jan. 23, 2022 - A ceremony about science and technology developments in Iran highlighted brain stimulation and cognitive technologies. (Source: IFP)

Studies Investigate Vagus Nerve Stimulation in Posttraumatic Stress Disorder

Jan. 22, 2022 - A news feature describes emerging evidence for use of noninvasive vagus nerve stimulation in treating posttraumatic stress disorder. (Source: Psychology Today)

Center Joins Study of Brain Stimulation in Alzheimer's Disease

Jan. 21, 2022 - The Allegheny Health Network is joining the ADvance II phase 3 clinical study that explores the safety and efficacy of deep brain stimulation of the fornix to treat mild Alzheimer's disease. (Source: PR Newswire)

Presentation Focuses on Telehealth in Neuromodulation Services

Jan. 20, 2022 - A presentation concerned the role telehealth would play in access to neuromodulation services. (Source: NeuroNews)

News Report Features Emerging Neuromodulation Treatments

Jan. 19, 2022 - A news report presents emerging noninvasive neurostimulation methods for chronic conditions such as rheumatoid arthritis or tremor. (ABC News)

Researchers Study Vagus Nerve Stimulation in Pilot Trial in Heart Failure Patients

Jan. 13, 2022 - A team of authors has published results of a pilot randomized clinical trial of the effect of transcutaneous vagus nerve stimulation on inflammation, heart function, and exercise capacity in patients with heart failure with preserved ejection fraction. (Source: Journal of the American Heart Association)

Startup Raises €6 Million for Development of Functional Electrical Stimulation in Quadriplegia

Jan. 5. 2022 - The University of Montpellier's spinout Neurinnov has raised €6 million in a combination of seed-round investment and non-dilutive financing. The company is working on a neural implant to help restore grip for individuals with quadriplegia. (Source: JIBEOP.com)

Company Announces Expanded Labeling for Spinal Cord Stimulation System

Jan. 19, 2022 - Nevro Corp. announced FDA approval for expanded labeling for its 10 kHz spinal cord stimulation system for treatment of non-surgical refractory back pain. Separately, Nevro also announced data presented in 17 clinical abstracts at the North American Neuromodulation Society annual meeting, including clinical trial data at 12 and 18 months, concerning use of 10 kHz spinal cord stimulation in patients with chronic pain.(Source: PR Newswire)

Company Announces Breakthrough Device Designation Pertaining to Treatment of Peripheral Neuropathy

Jan. 18, 2022 - NeuroMetrix, Inc. announced its Quell noninvasive neurostimulator has received U.S. FDA Breakthrough Device designation for the treatment of chemotherapy-induced peripheral neuropathy. (Source: Globe Newswire)

Army, Air Force Evince Interest in Noninvasive Neurostimulation

Jan. 17, 2022 - A video report of nearly 5 minutes details how the U.S. Army and Air Force are trying noninvasive vagus nerve stimulation or noninvasive brain stimulation as a potential way to improve alertness and focus during training, as well as for its potential to treat post-traumatic stress disorder. (Source: Army Times)

$9.8 Million Competition Announced for Nerve Stimulation for Autonomic Function

Jan. 18, 2022 - The U.S. National Institutes of Health (NIH) announced it has launched the first phase of its $9.8 million Neuromod Prize that seeks to accelerate peripheral nerve stimulation to "independently regulate two or more desired autonomic functions without unintended effects on non-target organs". The prize was initiated under the NIS Common Fund's Stimulating Peripheral Activity to Relieve Conditions (SPARC)  (Source: National Institutes of Health)

Study Will Evaluate Simultaneous Implant of Spinal Fusion and Neuromodulation Devices in Chronic Low Back Pain Patients

Jan. 13, 2022 - Syner Fuse, Inc. announced the first implantation in a proof-of-concept study of spinal fusion hardware and a dorsal root ganglion neurostimulator simultaneously in an individual suffering from chronic low back pain. (Source: PR Newswire)

Three-Month Data Presented Concerning Low-Energy Spinal Cord Stimulation

Jan. 13, 2022 - Three-month data were presented from a clinical trial of differential target multiplexed spinal cord stimulation endurance therapy. (Source: Spinal News International)

Adaptive Spinal Cord Stimulation System Receives Breakthrough Device Designation

Jan. 13, 2022 - Wavegate Corporation announced the FDA has granted Breakthrough Device designation for its optical reflectometry system for closed-loop adaptive modulation of spinal cord stimulation. (Source: KPVI)

Startup Closes $10 Million Funding Round

Jan. 11, 2022 - GrayMatters Health announced closure of a $10 million Series A funding round, and plans to apply the funds towards further commercial development of its device for digital self-neuromodulation therapy to support emotional regulation. (Source: Cision)

Noninvasive Neurostimulation Methods Investigated for Long COVID

Jan. 5, 2022 - A news feature discusses recent lines of research into noninvasive neurostimulation as a potential treatment for long COVID. (Source: IEEE Spectrum)

PTSD Treatment Receives Breakthrough Device Designation

Jan. 12, 2022 - The company electroCore, Inc. announced its noninvasive vagus nerve stimulation system received Breakthrough Device designation from the FDA for treatment of post-traumatic stress disorder. (Source: Globe Newswire)

Article Surveys the State of Therapeutic Brain Stimulation Development

Jan. 12, 2022 - A news feature describes research into deep brain stimulation or transcranial magnetic stimulation to potentially treat psychiatric or other conditions. (Source: STAT)

Closed-Loop Spinal Cord Stimulation Two-Year Outcomes Reported

Jan. 8, 2022 - In a secondary analysis, a team of co-authors published two-year outcomes in a randomized controlled trial of closed-loop spinal cord stimulation for chronic back and leg pain. (Source: JAMA Neurology)

Team Unveils a Wearable Noninvasive Brain Stimulation Device

Jan. 7, 2022 - A wearable device its inventors say delivers pulsed magnetic stimulation made a debut at the Consumer Electronics Show, and is being presented as being designed for creation of a meditative state. (Source: Medscape)

Transcranial Direct Current Stimulation Studied in Long COVID

Jan. 7, 2022 - A news feature that references past or future studies discusses neurostimulation as a potential therapy for long COVID. (Source: IFL Science!)

Two-Year Results Published in Clinical Trial of Neurostimulation for Chronic Pain

Jan. 3, 2022 - An article in press presents two-year results in a randomized controlled trial of restorative neurostimulation in patients with chronic disabling back pain secondary to multifidus muscle dysfunction. (Source: Neuromodulation: Technology at the Neural Interface)

Guidelines Published on Spinal Cord Stimulation Surgical Technique

Jan. 1, 2022 - The International Neuromodulation Society’s Neurostimulation Appropriateness Consensus Committee has published recommendations for surgical technique -- including preoperative assessment and postoperative management -- for spinal cord stimulation for the treatment of chronic pain. (Source: Neuromodulation: Technology at the Neural Interface)

International Guidance Published on Cervical Neurostimulation

Jan. 1, 2022 - A multispecialty group of physicians convened by the International Neuromodulation Society, through the  International Neuromodulation Society’s  Neurostimulation Appropriateness Consensus Committee, has published evidence-based guidance on the use of cervical neuromodulation. (Source: Neuromodulation: Technology at the Neural Interface)

Company Announces Expanded MRI Compatibility Approval

Jan. 4, 2022 - Abbott announced that the FDA has approved expanded MRI compatibility labeling of its XR spinal cord stimulation system with Octrode leads. (Source: Mass Device)