2022 News Briefs - International Neuromodulation Society

Earlier News:

Company Highlights Closed-Loop Technology Presentations

May 18, 2022 - Saluda Medical announced scientific presentations at the International Neuromodulation Society 15th World Congress concerning its closed-loop spinal cord stimulation system. (Source: PR Newswire)

Noninvasive Brain Stimulation Pivotal Trial Planned

May 18, 2022 - Flow Neuroscience announced it will launch a U.S. pivotal trial of its transcranial direct current stimulation headset in the treatment of major depressive disorder. (Source: NeuroNews)

Results Reported in tDCS Trial in COVID Patients with Respiratory Distress

May 1, 2022 - A sham-controlled trial evaluated effects of active high-definition transcranial direct current stimulation plus respiratory rehabilitation on moderate-to-severe acute respiratory distress syndrome in patients with COVID-19, who received the treatment for up to 10 days in the intensive care unit. (Source: Brain Stimulation Journal)

18-Month Data Presented from Patients Who Received Neurostimulation Treatment for Painful Diabetic Neuropathy

May 14, 2022 - Data from 18 months of treatment were presented at the AACE Annual Scientific and Clinical Conference regarding patients who received spinal cord stimulation for painful diabetic neuropathy. (Source: Healio)

Survey: Providers' Goals for Neuromodulation Therapy for Chronic Pain

May 10, 2022 - A three-part survey of 88 healthcare providers at the 2nd Joint Congress of the International Neuromodulation Society European Chapters in 2021 asked clinicians: their goals for treating pain pains with neuromodulation, factors expected to change, and definition of success; for instance, increased mobility or quality of life. (Source: Neuromodulation: Technology at the Neural Interface)

Noninvasive Brain Stimulation System Receives FDA Clearance for OCD

May 10, 2022 - Neuronetics, Inc. announced its transcranial magnetic stimulation system received FDA approval as an adjunct treatment for adults with obsessive compulsive disorder. (Source: Globe Newswire)

Heart-Failure Neurostimulation Device Receives MRI-Conditional Labeling from the FDA

May 9, 2022 - CVRx, Inc. announced it received FDA approval for magnetic resonance-conditional labeling of its Barostim system for treatment of heart failure (in Europe, the system is also CE marked for resistant hypertension). (Source: Globe Newswire)

Company Raises $64 Million in Financing

May 9, 2022 - BlueWind Medical, Ltd., announced it has closed a series B funding round of $64 million and plans to file later this year for FDA marketing clearance of its implantable tibial neuromodulation device for overactive bladder. (Source: PR Newswire)

Video Podcast Previews INS 15th World Congress

May 9, 2022 - In a 4-minute overview video, International Neuromodulation Society President A/Prof. Marc Russo previews the upcoming INS 15th World Congress, which will have simultaneous streams on pain, brain, and organ stimulation. He said the meeting will offer research, reviews, techniques, and information about startups and medical-device ventures, as well as opportunities for mentoring and interaction with international colleagues. (Source: touchNeurology)

Article: Novel Deep Brain Stimulation Targets for Movement Disorder

May 5, 2022 - A summary presents novel deep brain stimulation targets for movement disorder, as described in a recent journal article. (Source: DocWire News)

Article Covers Vagus Nerve Stimulation for Depression

May 5, 2022 - An article summarizes a recent overview of vagus nerve stimulation as a treatment for therapy-resistant depression. (Source: Medscape)

Outcome-Survey Results Published Regarding Temporary Neurostimulation for Pain

May 4, 2022 - Results were published from patients surveyed between 3 and 30 months after they had received 60 days of peripheral nerve stimulation for pain. (Source: Future Medicine)

Clinical Trial of Neurostimulation for Adolescents with Epilepsy Enrolls First Patient

May 4, 2022 - NeuroPace, Inc. announced the first patient was enrolled in a clinical trial of its responsive neurostimulation system in adolescents with drug-resistant focal epilepsy. (Source: BioSpace)

Company's Brain-Cumputer Interface Clinical Trial Enrolls First U.S. Patient

May 4, 2022 - Synchron Inc. has enrolled its first U.S. patient in a clinical trial of its Stentrode, an endovascular brain-computer interface. (Source: Bloomberg News)

Innovators Describe Neurostimulation Approach to Treat Foot Drop

April 30, 2022 - An article describes a lower-extremity functional electrical stimulation system that uses dual stimulation to address foot drop. (Source: Neurotech Reports)

Article Describes Neurostimulator Lead Placement Technique

April 15, 2022 - A team of physicians has published a technique for S1 dorsal root ganglion stimulation lead placement. (Source: Pain Medicine)

Retrospective Study Examines Perceived Pain Reduction from Different Frequencies of Spinal Cord Stimulation

April 28, 2022 - A retrospective study of 237 pain patients treated from 2004 to 2020 assessed perceived pain reduction, comparing results between males and females who received spinal cord stimulation at either high or low frequency. (Source: Science Daily)

Machine-Learning Models in Development for Selection of Candidates for Spinal Cord Stimulation

April 28, 2022 - Using a prospectively collected database, researchers are developing predictive models regarding which patients might be anticipated to benefit from spinal cord stimulation for chronic pain. (Source: Florida Atlantic University)

Analysis: Noninvasive Brain Stimulation and Smoking Cessation

April 28, 2022 - Researchers published a systemic review and meta-analysis of noninvasive brain stimulation in smoking cessation programs. (Source: News.am)

Patients in the U.K. Undergo Clinical Trial with a Skull-Implanted Neurostimulator for Parkinson's Disease

April 27, 2022 - An article describes some of the first clinical experience with an investigational neurostimulation device implanted into the skull as a potential treatment for the motor effects of Parkinson's disease. (Source: Mirror)

Company Launches Neurostimulation Trial Digital Health App Upgrade

April 28, 2022 -- Abbott announced release of an upgraded digital health app for tracking patients undergoing a neurostimulation trial for chronic pain. (Source: PR Newswire)

Company Announces Peripheral Nerve Stimulation Trial for Chronic Knee Pain

April 22, 2022 - Stimwave Technologies announced the launch of a series of clinical trials, starting with a trial that monitors its peripheral nerve stimulation system in patients with chronic knee pain. (Source: NeuroNews)

Company Announces Noninvasive Vagus Nerve Stimulation Study in Heart Patients

April 21, 2022 - Parasym Ltd. issued a press release about a study published in January of its noninvasive vagus nerve stimulation system in patients with heart failure with preserved ejection fraction. (Source: Yahoo! Finance)

Paper Summarizes Survey Results of Primary-Care Residents' Knowledge of Neuromodulation for Back Pain in Rural Clinics

April 21, 2022 - Researchers at the University of Arkansas surveyed rural family medicine residents for familiarity with neuromodulation as a treatment for post-laminectomy syndrome. (Source: Journal of Pain Research)

Review Analyzes Findings in Noninvasive Brain Stimulation in Patients with OCD

April 21, 2022 - A news article recounts publication in Psychiatry Research of a systemic review and meta-analysis about repetitive transcranial magnetic stimulation in the treatment of obsessive compulsive disorder. (Source: Dermatology Advisor)

Narrative Review Focuses on Patient Selection for Spinal Cord Stimulation

April 20, 2022 - A group of international authors prepared a narrative review that presents a sequential decision-making model for patient selection for spinal cord stimulation in the treatment of chronic pain. (Source: Journal of Pain Research)

Company Announces Further Study of Its Neurostimulator

April 19, 2022 - According to a company announcement, a U.S. Air Force program plans to further research the electroCore, Inc.'s noninvasive vagus nerve stimulation device to potentially enhance training performance in the environment of intelligence, surveillance and reconnaissance. (Source: Street Insider)

Device Company Launches Its Sacral Neuromodulation System in the United States

April 19, 2022 - Axonics announced a comprehensive U.S. launch of its sacral neuromodulation system that received FDA approval in March. (Source: NeuroNews)

Device Company Announces Issuance of New Patents

April 19, 2022 - NeuraLace Medical, Inc. announced issuance of two U.S. patents related to its technology for the treatment of peripheral nerve pain. (Source: PR Newswire)

INS 15th World Congress Innovations Day Preconference Program Announced

April 15, 2022 - The International Neuromodulation Society is holding its sixth World Congress preconference for the global neuromodulation innovation and investment community, "Neuromodulation without Borders," on May 22, 2022 in Barcelona. The event features presentations by emerging companies, entrepreneurs, medical device industry representatives and members of the investment community. (Source: INS)

Company Receives FDA Approval for Deep Brain Stimulation Software

April 12, 2022 - Boston Scientific Corporation has received FDA approval for guided programming software, STIMVIEW XT, used in conjunction with its Vercise Genus deep brain stimulation system. (Source: Neurology Live)

Column Describes Emerging Directions of Neural Interface Therapies

April 12, 2022 - A column surveys investment and development of brain-stimulation or bioelectronic medicine therapies, citing examples of investigational approaches and emerging companies. (Source: Octopus Ventures)

Study Protocol Published for Brain Stimulation-Assisted Cognitive Training Post-COVID

April 11, 2022 - Investigators published a phase IIb trial study protocol for studying brain stimulation-assisted cognitive training in patients with post-COVID-19 cognitive impairment. (Source: BMJ Open)

Case Published of Spinal Cord Stimulation in a Patient with Orthostatic Hypotension

April 6, 2022 - Clinicians reported a case of a woman with orthostatic hypotension who frequently fainted, describing use of a spinal cord stimulator that targets nerves that constrict arteries in the legs and trunk when activated. (Source: Live Science)

Company Announces a Reimbursement Decision in Germany

April 5, 2022 - Stimwave Technologies announced the German Institute for Hospital Remuneration granted two of the company's neurostimulator products a stauts that provides a pathway for potential additional hospital reimbursement. (Source: Business Wire)

Clinicians Report Results of Study of Vagus Nerve Stimulation in Hospitalized COVID Patients

April 8, 2022 - Results were published from the SAVIOR I randomized controlled trial of noninvasive vagus nerve stimulation to treat respiratory symptoms and inflammation biomarkers  in patients hospitalized with COVID-19. (Source: Frontiers in Neurology)

Research Into Transcranial Magnetic Stimulation Explores Targeting with Brain Imaging for Depression Treatment

April 7, 2022 - An article describes theta burst transcranial magnetic stimulation in depression and individual tailoring of the location using functional magnetic resonance imaging (fMRI). Another article describes using fMRI and diffusion tensor imaging to target deeper areas of the brain. (Source: Discover Magazine

Company Announces Results of Neurostimulation Study in Acute Migraine

April 6, 2022 - Cefaly Technology announced results of a Phase 3 clinical trial of external trigeminal nerve stimulation for acute treatment of migraine attacks. (Source: Medical Dialogues)

Presentation Covers Findings in Noninvasive Nerve Stimulation After Stroke

April 6, 2022 - Data about safety and feasability were presented in a sham-controlled study of noninvasive vagus nerve stimulation administered up to six hours after stroke. (Source: Neurology Live)

Company Announces a Certification for Its Latest Spinal Cord Stimulation Platform

April 5, 2022 - Stem-Tronics.com announced certification for a next-generation implanted neurostimulator for pain management. (Source: EINPresswire)

Collaboration Centers on Potential Intervention for Withdrawal Symptoms in Opioid Use Disorder

April 5, 2022 - Battelle and Spark Biomedical, Inc. announced they will collaborate on a pilot study to remotely detect biomarkers of withdrawal from opioid use disorder, as a preliminary step toward developing a closed-loop neurostimulation approach to opioid withdrawal. (Source: Business Wire)

Analysis Assesses Uptake of Spinal Cord Stimulation in England

April 5, 2022 - A statistical analysis from 2010 - 2020 assessed the uptake of spinal cord stimulation across the National Health Service in England. The therapy has been recommended there as a management option for chronic neuropathic pain since 2008. (Source: Neuromodulation: Technology at the Neural Interface)

Pre-Commercial Brain-Stimulation Spinout Announces Funding

April 5, 2022  - A Swiss spinout that is developing an implantable brain-stimulation device, Neurosoft Bioelectronics Ltd., announced it has received funding of nearly $3 million, from the SERI-Funded European Innovation Council Accelerator Grant and a share of the $165,000 USD through the European Research Council Proof-of-Concept Grant, as well as a $100,000 convertible note. The company is pursuing an initial application in epilepsy. (Source: Send2Press)

Brain-Computer-Interface Startup Raises $10 Million in Seed Funding

March 30, 2022 - Inner Cosmos Inc. announced it raised $10.25 million in seed funding as it plans to pursue a brain-computer interface to potentially treat depression. (Source: Bloomberg)

Company Receives FDA Clearance for Tear-Production Device

March 31, 2022 - Olympic Ophthalmics announced it has received clearance from the FDA for a tear-production neuromodulation device, and has three ongoing clinical trials. (Source Medical Device Network)

In Preclinical Work, Collaborators Demonstrate a Proof-of-Concept Peripheral Nerve Stimulator

March 31, 2022 - A team of co-authors in Texas published a proof-of-concept demonstration of an endovascular peripheral nerve stimulator. (Source: EurekAlert)

Analysis of Cortical Signals Shows Areas of Grasp and Speech Encoding

March 31, 2022 - In a person with tetraplegia, researchers decoded signals for grasping and speech from a cortical circuit they say might be considered for a target for a brain-computer interface. (Source: Neuron)

Researchers Use Neuromodulation Data from Dystonia Patients to Model Electrode Placement and Investigate Stimulation Effects

March 31, 2022 - A paper presents deep brain stimulation effects in 80 patients with either cervical or generalized dystonia, retrospectively investigates tracts associated with improvements, and maps optimal stimulation sites. (Source: PNAS)

Retrospective Analysis Reports Procedure-Related Outcomes for Spinal Cord Stimulation

April 2022 - In a retrospective analysis of procedure-related outcomes, physicians evaluated a readmission database for 3,737 patients who received spinal cord implantation between 2013 and 2017. (Source: Anesthesia & Analgesia)

Brain-Computer Interface Study Results to Be Presented, Further Clinical Study Planned

March 30, 2022 - Results will be presented at an upcoming meeting of an Australian study in which four people with quadriplegia had a brain-computer interface threaded into a vein near the motor cortex. An ensuing clinical study in Pittsburgh, PA will map sensorimotor activity. (Source: Pittsburgh Post-Gazette)

Patients Implanted in a Tibial Nerve Stimulation Pivotal Trial for Overactive Bladder

March 25, 2022 - Medtronic announced it completed the first implants in a pivotal trial of its investigational tibial nerve stimulation device in patients with overactive bladder. (Source: Mass Device)

Researchers Study Noninvasive Brain Stimulation in Stroke Recovery

March 25, 2022 - A study by researchers in Germany assessed transcranial direct current stimulation in augmenting motor recovery following stroke, whose physical rehabilitation involved using virtual tasks performed via a personalized robotic system. (Source: Medical Xpress)

Study Analyzes Comparative Treatment Costs, With or Without Vagus Nerve Stimulation, in Children with Drug-Resistant Epilepsy

March 25, 2022 - In a study that drew on data from 44 children's hospitals in the U.S., researchers analyzed comparative treatment costs for children with drug-resistant epilepsy who were treated either with anti-seizure medication alone (n=3471), or with anti-seizure medication and vagus nerve stimulation (n=1113). (Source: Science Daily)

Results Presented in Randomized Trial of Spinal Cord Stimulation

March 24, 2022 - Data from a clinical trial of high-frequency spinal cord stimulation were presented at the 2022 annual meeting of the North American Neuromodulation Society. (Source: NeuroNews)

Researchers Start Study of Noninvasive Brain Stimulation in Alzheimer's Disease

March 23, 2022 - Researchers at the Medical University of South Carolina are beginning a study of the effects of transcranial magnetic stimulation in the progression of Alzheimer's disease. (Source: WCSC)

Observations Published of Vagus Nerve Stimulation Effects on Autistic Behaviors

March 21, 2022 - An observational study in pediatric patients who were being treated with vagus nerve stimulation for drug-resistant epilepsy reported the treatment effects on autistic behaviors. (Source: DocWire News)

Data Presented from Randomized Trial of Dorsal Root Ganglion Stimulation at Frequencies as Low as 20Hz

March 15, 2022 - A presentation at the 2022 annual meeting of the North American Neuromodulation Society covered a randomized study of dorsal root ganglion stimulation in chronic pain patients at frequencies from 20Hz to 80Hz. (Source: NeuroNews)

Physicians Study Spinal Cord Stimulation and Respiratory Function in Spine-Injury Patients

June 2022 - A research team assessed if high epidural spinal cord stimulation at a location related to intercostal muscles could facilitate respiratory function in two patients who were on mechanical stimulation due to spinal cord injury. (Source: Respiratory Physiology & Neurobiology)

Authors Report Response in Pain Patients During 60 Days of Percutaneous Peripheral Nerve Stimulation

March 14, 2022 - Based on data from several hundred patients who had up to two months of percutaneous peripheral nerve stimulation to various targets, an article postulates that length may help anticipate prospective longer-term responders. (Source: Journal of Pain Research)

Authors Report Response in Pain Patients During 60 Days of Percutaneous Peripheral Nerve Stimulation

March 14, 2022 - Based on data from several hundred patients who had up to two months of percutaneous peripheral nerve stimulation to various targets, an article postulates that length may help anticipate prospective longer-term responders. (Source: Journal of Pain Research)

Authors Report Response in Pain Patients During 60 Days of Percutaneous Peripheral Nerve Stimulation

March 14, 2022 - Based on data from several hundred patients who had up to two months of percutaneous peripheral nerve stimulation to various targets, an article postulates that length may help anticipate prospective longer-term responders. (Source: Journal of Pain Research)

Column Looks Ahead in the Field of Neuromodulation

March 9, 2022 - A column provides perspectives on the future of neuromodulation. (Source: NeuroNews)

Experts Discuss Tibial Nerve Stimulation Devices for Overactive Bladder

March 9, 2022 - Two clinicians discussed their experience and perspectives on tibial nerve stimulation devices for overactive bladder. (Source: Urology Times)

Study Looks at Minimally Invasive Nerve Stimulation in Sexual Dysfunction

March 8, 2022 - An interview discusses findings presented at a recent scientific meeting of a randomized controlled study of percutaneous tibial nerve stimulation in female sexual dysfunction. (Source: Urology Times)

Company Announces Its Stimulation Device Received FDA Clearance

March 8, 2022 - MyndTec announced FDA clearance for its electrical stimulation system for motor recovery following stroke or spinal cord injury. (Source: Yahoo! Life)

Company Receives FDA Clearance for Device to Address Foot Drop

March 8, 2022 - Cionic announced FDA Clearance for its Neural Sleeve, which delivers electrical stimulation to the legs of people with foot drop and muscle weakness. (Source: MobiHealthNews)

FDA Approval Announced for Spinal Cord Stimulation System

March 8, 2022 - Saluda Medical announced FDA approval for its closed-loop spinal cord stimulation system for the treatment of chronic intractable pain of the trunk and/or limbs. (Source: PR Newswire)

Company Announces FDA Approval of Sacral Neuromodulation System

March 7, 2022 - Axonics Modulation Technologies announced it received FDA approval for its new sacral neuromodulation system. (Source: Mass Device)

TV Segment Features Research Into an Injectable Electrode

March 7, 2022 - A television segment featured an injectable neurostimulation electrode, which the researchers reportedly hope to submit for FDA clearance over the next two years. (Source: 9and10news.com)

Company Begins Grant-Funded Clinical Trial in Post-Stroke Spasticity

March 7, 2022 - PathMaker Neurosystems, Inc. announced it has begun a U.S. multi-center clinical trial to evaluate its neurostimulation device in post-stroke upper-limb spasticity. The trial is funded by a $4.9M NINDS Cooperative Research to Enable and Advance Translational Enterprises for Devices (CREATE Devices) grant from the National Institute of Neurological Disorders and Stroke. (Source: Globe Newswire)

International Neuromodulation Society Announces Its 15th World Congress

March 7, 2022 - The International Neuromodulation Society issued a news release on the INS 15th World Congress to raise awareness of neuromodulation and to encourage attendance. (Source: EurekAlert)

Company Plans Phase II Trial of Noninvasive Neurostimulation for Neonatal Opioid Withdrawal Syndrome

March 3, 2022 - Spark Biomedical, Inc. has a $2.49 million grant from the National Institute of Health HEAL Initiative and plans a Phase II trial to evaluate its transcutaneous auricular nerve stimulation system as adjunctive therapy for neonatal opioid withdrawal syndrome. (Source: Yahoo! Finance)

Company Presents Wearable Brain Stimulation Device at Mobile Technology Meeting

March 3, 2022 - Neuroelectrics presented its noninvasive brain stimulation system at a mobile technology meeting last week in Barcelona. The company, which is based in Barcelona and Boston, is developing its wearable device to potentially help people living with seizures, sleep disorders, and autism. (Source: Interesting Engineering)

Noninvasive Brain Stimulation Studied in Cannabis Use Disorder

March 3, 2022 - Results were published of a study of transcranial magnetic stimulation in persons with schizophrenia who have cannabis use disorder. (Source: Science Daily)

Device Company Raises $125 Million in Equity Financing

March 2, 2022 - Saluda Medical announced completion of a $125 million round of equity financing, to support commercialization, research, and clinical development of the medical device company's neuromodulation portfolio. (Source: The Street)

FDA Approves Neurostimulator for Urinary Indication

March 2, 2022 - The FDA issued premarket approval for Valencia Technologies' eCoin leadless tibial neurostimulator to treat urinary urge incontinence. (Source: Urology Times)

Recruitment Underway in Study of Brain Stimulation for Obesity

March 2, 2022 - Pittsburgh-based Allegheny Health Network in Pennsylvania is recruiting six participants for a second phase of the clinical trial investigating deep brain stimulation of the hypothalamus in patients who have a body mass index above 50 with associated health risks, and who have not had sustainable results from gastrointestinal bypass surgery. (Source: Boston 25 News)

Review: Neuromodulation for Painful Diabetic Neuropathy

Feb. 28, 2022 - A review presents evidence on neuromodulation interventions for painful diabetic neuropathy. (Source: Current Pain and Headache Reports)

Parkinson's Patient Receives Deep Brain Stimulation Treatment for the First Time in Ireland

Feb. 27, 2022 - A newspaper article features the first Parkinson's disease patient to undergo deep brain stimulation in Ireland, rather than having to travel for the treatment. (Source: Independent.ie)

Company Announces First Investigational Implantation of Its Neurostimulation for Obstructive Sleep Apnea

Feb. 25, 2022 - LivaNova announced the first patient has been implanted in a clinical trial of its neurostimulator for obstructive sleep apnea. (Source Mass Device)

Company Plans to Market Brain-Computer Array in 2022

Feb. 23, 2022 - A news feature about research into converting thought into text via a brain-computer interface includes comments from an interview with the co-founder of Blackrock Neurotech, whose electrode array is expected to undergo commercialization this year. (Source: Forbes)

Researchers Present Retrospective Study Concerning Spinal Cord Stimulation

Feb. 25, 2022 - A meeting abstract in late 2021 presented single-institution data from 2004 - 2018 concerning length of benefit of spinal cord stimulation and impacts on opioid pain medication use. (Source: Pain Medicine News)

Study Planned of Vagus Nerve Stimulation for Prevention of Depression Relapse

Feb. 23, 2022 - A protocol was published for a longitudinal study of the effect and neural mechanisms of transcutaneous vagus nerve stimulation for relapse prevention in major depressive disorder. (Source: DocWire News)

Pilot Study Features Noninvasive Neurostimulation to Address Abnormal Heart Rhythm

Feb. 21, 2022 - A double-blind randomized pilot study published in JAMA Cardiology evaluated a single session of transcutaneous magnetic stimulation of the left stellate ganglion vs. sham in patients experiencing ventricular tachycardia. (Source: Medical Dialogues in Cardiology)

Review Focuses on Autonomic Neuromodulation and Atrial Fibrillation After Heart Surgery

Feb. 14, 2022 - A review article summarized findings of clinical studies of autonomic neuromodulation therapies and the risk that cardiac surgery patients may develop postoperative atrial fibrillation. (Source: BioSpace)

Neurostimulator Receives Breakthrough Designation

Feb. 22, 2022 - The Precisis AG's subcutaneous neurostimulator, Easee, has received breakthrough device designation from the FDA as a potential approach to prevent or mitigate seizures. (Source: BioSpace)

Findings Published from Bimodal Neuromodulation Study in Tinnitus

Feb. 21, 2022 - The company Neuromod Devices welcomed findings of an independent study in Germany of its bimodal neuromodulation device in participants with tinnitus. (Source: NeuroNews)

Brain-Stimulation Device Startup Joins Technology Incubator

Feb. 21, 2022 - Actipulse Neuroscience is joining the technology incubator Y Combinator. The startup is working on home-use noninvasive brain stimulation for depression or neurodegenerative conditions. (Source: Healthcare Tech Outlook)

Authors Publish Findings of Preliminary Brain Stimulation Study in Alzheimer's Disease

Feb. 9, 2022 - An international team of authors published a preliminary study of transcranial focused ultrasound to the hippocampus in Alzheimer's disease. (Source: Journal of Personalized Medicine)

Study Examines Spinal Cord Stimulation Disparities

April 2022 - Researchers published an analysis of a 2016-2018 U.S. inpatient sample that examined racial disparities in cost and utilization for patients receiving inpatient spinal cord stimulation for chronic pain. (Source: Journal of Clinical Neuroscience)

Australian Charity Advocates for Research into Neurostimulation for Spinal Cord Injuries

Feb. 22, 2022 - An actress from Australian television went on the air to discuss her husband's paralysis in support of a request by SpinalCure Australia to establish a national program for treatment and research into neurostimulation for spinal cord injuries. (Source: 7news.com.au)

Company's Sacral Neuromodulation Device Receives Approval in the U.S.

Feb. 22, 2022 - The FDA has approved a sacral neuromodulation device from Medtronic, the InterStim X. (Source: Mass Device)

Neurostimulator Company Raises $104 Million in Equity Financing

Feb. 18, 2022 - Device company Nalu Medical, Inc. closed a $104 million equity round of financing.(Source: FinSMEs)

Study Documents Effects of Neurostimulation in Patients Being Weaned from Mechanical Ventilation

Feb. 15, 2022 - In a randomized, controlled, open-label trial researchers reported on transient transvenous phrenic nerve stimulation in patients who were reliant on artificial ventilation and had diaphragm dysfunction; the authors documented the effect of the neurostimulation on both weaning from the ventilator and on maximal inspiratory pressure. (Source: Physician's Weekly)

Company Announces New Patent for Spinal Neuromodulation Device

Feb. 15, 2022 - Privately held SynerFuse, Inc. announced issuance of a U.S. patent concerning direct surgically open placement of a neuromodulation device over the dorsal root ganglion. Earlier, the company announced a patent that covers combined spinal fixation and neuromodulation to treat a spinal injury and chronic lower back pain. (Source: PR Newswire)

Study to Explore Noninvasive Brain Surgery Following Mild Traumatic Brain Injury in Veterans

Feb. 13, 2022 - A three-year, $4 million study funded by the U.S. Department of Defense will investigate transcranial direct current stimulation and transcranial magnetic stimulation in veterans who have had cognitive issues due to mild traumatic brain injury incurred within the last 20 years. (Source: Rio Rancho Observer)

Meta-Analysis Summarizes Studies of TENS for Pain

Feb. 10, 2022 - A team of authors published a systemic review and meta-analysis of studies concerning the efficacy and safety of transcutaneous electrical nerve stimulation for acute and chronic pain. (Source: BMJ Open)

Peer-Review Article Presents 12-Month Results in Spinal Cord Stimulation Clinical Trial

Feb. 11, 2022 - Clinicians published 12-month results of a randomized controlled trial of treatment of nonsurgical refractory back pain with 10 kHz spinal cord stimulation. (Source: Journal of Neurosurgery)

Authors Describe Development of Remote Device Programming Platform

Feb. 10, 2022 - A team of co-authors describe development of a remote-care platform for patients with an implanted neuromodulation device. (Source: Scientific Reports)

Segment Highlights Spinal Cord Stimulation Research for Post-Paralysis Rehabilitation

Feb. 10, 2022 - A television segment features a man with paraplegia who participated in a research study into spinal cord stimulation for recovery of some mobility, and his wedding to a caregiver on the 10-year anniversary of the accident that paralyzed him. (Source: WNDU)

FDA Schedules Medical Device Q&A Webinars for March

Jan. 25, 2022 - The U.S. FDA announced a March 1 webinar for members of industry and other stakeholders to address its final guidance, Principles for Selecting, Developing, Modifying and Adapting Patient-Reported Outcome Instruments for Use in Medical Device Evaluation. Also, the FDA will hold a March 22 webinar on its guidance, Patient Engagement in the Design and Conduct of Medical Device Clinical Studies. (Source: FDA Center for Devices and Radiological Health)

Feasibility Trial Involves Novel Brain Stimulation Device

Feb. 8, 2022 - A news feature describes a feasibility trial in the U.K. of a novel closed-loop implanted neurostimulator to target the pedunculopontine nucleus in patients with Parkinson's-like multiple systems atrophy. The research is aimed at identifying biomarkers of the disease state throughout the day and night and ultimately to develop stimulation patterns to manage symptoms and improve sleep. (Source: Medical Xpress)

Journal Article Summarizes Neuromodulation Treatments for Chronic Daily Headache

Feb. 7, 2022 - A team of co-authors in Italy reviewed the literature on the use of central and peripheral neuromodulation techniques for chronic daily headache. (Source: Current Pain and Headache Reports)

Article Reports Neurostimulation Treatment in Two Cases of Long COVID

Feb. 7, 2022 - In published findings concerning two patients who had symptoms of long COVID, authors report changes after administering alternating current stimulation of the eyes and brain each day for 10 - 13 days. (Source: Neuroscience News)

Clinicians Report on Spinal Cord Stimulation in a Case of Low Back Pain

Feb. 7, 2022 - A case report describes neurostimulation treatment in a patient who had chronic axial low back pain. (Source: Cureus)

Company Developing Noninvasive Brain Stimulation Files for an Initial Public Offering

Feb. 4, 2022 - Nexalin Technology has filed for an initial public offering, seeking to raise $10 million for development of its transcranial electrical stimulation technology, which the company is developing for treatment of mental health conditions like anxiety, insomnia and depression. (Source: New Business Herald)

Article Presents Clinical Results of Neurostimulation for Leg Movement Following Spinal Cord Injury

Feb. 7, 2022 - Researchers in Switzerland published results of a three-person study in Nature Medicine in which participants who had lost the ability to walk due to spinal cord injury received neurostimulation and training to recover voluntary movement in their legs. (Source: CNN Health)

ALS-Focused Philanthropy Provides $250,000 Prize for Neurostimulation Research

Feb. 7, 2022 - PathMaker Neurosystems, Inc. announced receipt of a $250,000 CERF Medical Electronics Prize from the Cullen Education and Research Fund, a London-based philanthropy focused on amyotrophic lateral sclerosis. The announcement said the funding may facilitate initiation of clinical studies. The award is being shared with the academic research laboratory of the company founder, where preclinical studies took place. (Source: Globe Newswire)

Visual Prosthesis Device Receives Breakthrough Device Designation

Feb. 1, 2022 - The FDA gave Breakthrough Device designation to a visual prosthesis by Bionic Vision Technologies, which is being developed for restoring partial vision. (Source: news.com.au)

Participants Sought for Clinical Trial of Deep Brain Stimulation in Alzheimer's Disease

Feb. 3, 2022 - A study site in Texas is recruiting patients with mild Alzheimer's disease for a clinical trial taking place at centers in the U.S., Canada, and Germany evaluating the potential of deep brain stimulation to slow or halt the condition. (Source: Yahoo! Finance)

Investigators Recruit Participants for Trial of Brain Stimulation in Alcohol Use Disorder

Feb. 3, 2022 - Researchers are seeking participants for a clinical trial in Albuquerque, N.M. of transcranial alternating current stimulation in alcohol use disorder. (Source: UNM)

Review Discusses Ultrasound Neuromodulation

Jan. 25, 2022 - A review, "Ultrasound as a Neurotherapeutic: A Circuit- and System-Based Interrogation," includes discussion of low-intensity focused ultrasound for brain mapping and neuromodulation. (Source: Focus)

Company Announces Insurer's Expanded Treatment Coverage

Feb. 3, 2022 - Abbott announced that the health insurer UnitedHealthcare has updated a medical policy that increases access to the device maker's dorsal root ganglion stimulation device for the treatment of chronic pain. (Source: Mass Device)

Investigators Report Data on Peripheral Nerve Stimulation Following Lower-Limb Amputation

Jan. 27, 2022 - Data from a pilot study were reported at a recent meeting concerning peripheral nerve stimulation for pain in the three months following lower-limb amputation. (Source: Pain Medicine News)

Enrollment Complete in Clinical Trial of Noninvasive Vagus Nerve Stimulation

Feb. 1, 2022 - The company electroCore announced enrollment was complete in its randomized, sham-controlled study of noninvasive vagus nerve stimulation to reduce the development of ileus following colorectal surgery. The 97-patient study is taking place at two centers in England and is sponsored by the UK National Institute for Health Research. (Source: Yahoo! Finance

Meta-Analysis Looks at Clinical Trials of Neurostimulation for Swallowing Disorder

Jan. 31, 2022 - Neurostimulation was included in a special journal issue on "Advances in Management of Voice and Swallowing Disorders," in which a review and meta-analysis summarized randomized controlled trials of pharygeal and neuromuscular electrical stimulation in people with swallowing issues due to oropharyngeal dysphagia. (Source: Journal of Clinical Medicine)

Article Presents Findings About Remote Followup in Sacral Neuromodulation Patients

Jan. 28, 2022 - A survey published in Neuromodulation: Technology at the Neural Interface examined patients' attitudes toward remote programming and virtual care in followup appointments after implantation of a sacral neuromodulation system. (Source: DocWire News)

Authors Present Contributions to Neurosurgery by Women in Neuromodulation

Jan. 20, 2022 - An article recounts innovative contributions by women in neuromodulation to the field of stereotactic and functional neurosurgery. (Source: Frontiers in Human Neuroscience)

Company Announces Implantation of Its Device in a Rheumatoid Arthritis Patient

Jan. 26, 2022 - Galvani Bioelectronics announced the first implantation of a patient with rheumatoid arthritis in a UK-based feasibility study of the company's technology for splenic nerve stimulation. In parallel, patient enrollment is open at several centers in a larger U.S.-based feasibility study of the same technology in the same condition.  (Source: Business Wire)

Article Profiles the New President of NANS

Jan. 25, 2022 - Incoming North American Neuromodulation Society (NANS) President Salim Hayek, MD, PhD, is profiled in the current issue of NeuroNews. (Source: NeuroNews)

Investigators Use Brain-Imaging Studies in Overactive Bladder Patients Receiving Sacral Neuromodulation

Jan. 24, 2022 - In a prospective study that compared healthy controls to patients who received sacral nerve stimulation for overactive bladder (including groups who either had success or failure), researchers in China observed changes in activation of the left dorsolateral prefrontal cortex through neuroimaging in the course of investigating a possible central mechanism for the disorder. (Source: The Journal of Urology)

Authors Publish Evidence of Long-Term Effects of Transcranial Pulse Stimulation

Jan. 15, 2022 - A research team in Austria has published a study in healthy volunteers comparing sham and verum sessions of transcranial pulse stimulation (TPS) that was focused on the coritcal somatosensory representation of the right hand. One week before and after the session, they tested tactile spatial discrimination and dexterity. (Source: Journal of Translational Medicine)

FDA Approval for Spinal Cord Stimulation Systems Includes an Indication of Painful Diabetic Neuropathy

Jan. 24, 2022 - Medtronic announced FDA approval of two neurostimulators for treating chronic pain, including that associated with diabetic peripheral neuropathy. (Source: Mass Device)

Company Highlights Clinical Results in Migraine Prevention Research

Jan. 24, 2022 - The company electroCore Inc. announced results of a randomized clinical trial published in Cephalalgia investigating its noninvasive vagus nerve stimulation device in migraine. (Source: Healio)

Foundation Announces Clinical Trials on Noninvasive Neurostimulation in Parkinson's Disease

Jan. 4, 2022 - The Michael J. Fox Foundation announced two ongoing clinical trials of neurostimulation devices in Parkinson's disease; "Use of a Non-Invasive Brainstem Neuromodulation Device to Improve Neurovascular Status in Parkinson's Disease" and "Vibrotactile Coordinated Reset: A Non-invasive Treatment for Parkinson's Disease". (Source: Michael J. Fox Foundation)

Event in Iran Features R&D Involving Brain Stimulation and Other Technologies

Jan. 23, 2022 - A ceremony about science and technology developments in Iran highlighted brain stimulation and cognitive technologies. (Source: IFP)

Studies Investigate Vagus Nerve Stimulation in Posttraumatic Stress Disorder

Jan. 22, 2022 - A news feature describes emerging evidence for use of noninvasive vagus nerve stimulation in treating posttraumatic stress disorder. (Source: Psychology Today)

Center Joins Study of Brain Stimulation in Alzheimer's Disease

Jan. 21, 2022 - The Allegheny Health Network is joining the ADvance II phase 3 clinical study that explores the safety and efficacy of deep brain stimulation of the fornix to treat mild Alzheimer's disease. (Source: PR Newswire)

Presentation Focuses on Telehealth in Neuromodulation Services

Jan. 20, 2022 - A presentation concerned the role telehealth would play in access to neuromodulation services. (Source: NeuroNews)

News Report Features Emerging Neuromodulation Treatments

Jan. 19, 2022 - A news report presents emerging noninvasive neurostimulation methods for chronic conditions such as rheumatoid arthritis or tremor. (ABC News)

Researchers Study Vagus Nerve Stimulation in Pilot Trial in Heart Failure Patients

Jan. 13, 2022 - A team of authors has published results of a pilot randomized clinical trial of the effect of transcutaneous vagus nerve stimulation on inflammation, heart function, and exercise capacity in patients with heart failure with preserved ejection fraction. (Source: Journal of the American Heart Association)

Startup Raises €6 Million for Development of Functional Electrical Stimulation in Quadriplegia

Jan. 5. 2022 - The University of Montpellier's spinout Neurinnov has raised €6 million in a combination of seed-round investment and non-dilutive financing. The company is working on a neural implant to help restore grip for individuals with quadriplegia. (Source: JIBEOP.com)

Company Announces Expanded Labeling for Spinal Cord Stimulation System

Jan. 19, 2022 - Nevro Corp. announced FDA approval for expanded labeling for its 10 kHz spinal cord stimulation system for treatment of non-surgical refractory back pain. Separately, Nevro also announced data presented in 17 clinical abstracts at the North American Neuromodulation Society annual meeting, including clinical trial data at 12 and 18 months, concerning use of 10 kHz spinal cord stimulation in patients with chronic pain.(Source: PR Newswire)

Company Announces Breakthrough Device Designation Pertaining to Treatment of Peripheral Neuropathy

Jan. 18, 2022 - NeuroMetrix, Inc. announced its Quell noninvasive neurostimulator has received U.S. FDA Breakthrough Device designation for the treatment of chemotherapy-induced peripheral neuropathy. (Source: Globe Newswire)

Army, Air Force Evince Interest in Noninvasive Neurostimulation

Jan. 17, 2022 - A video report of nearly 5 minutes details how the U.S. Army and Air Force are trying noninvasive vagus nerve stimulation or noninvasive brain stimulation as a potential way to improve alertness and focus during training, as well as for its potential to treat post-traumatic stress disorder. (Source: Army Times)

$9.8 Million Competition Announced for Nerve Stimulation for Autonomic Function

Jan. 18, 2022 - The U.S. National Institutes of Health (NIH) announced it has launched the first phase of its $9.8 million Neuromod Prize that seeks to accelerate peripheral nerve stimulation to "independently regulate two or more desired autonomic functions without unintended effects on non-target organs". The prize was initiated under the NIS Common Fund's Stimulating Peripheral Activity to Relieve Conditions (SPARC)  (Source: National Institutes of Health)

Study Will Evaluate Simultaneous Implant of Spinal Fusion and Neuromodulation Devices in Chronic Low Back Pain Patients

Jan. 13, 2022 - Syner Fuse, Inc. announced the first implantation in a proof-of-concept study of spinal fusion hardware and a dorsal root ganglion neurostimulator simultaneously in an individual suffering from chronic low back pain. (Source: PR Newswire)

Three-Month Data Presented Concerning Low-Energy Spinal Cord Stimulation

Jan. 13, 2022 - Three-month data were presented from a clinical trial of differential target multiplexed spinal cord stimulation endurance therapy. (Source: Spinal News International)

Adaptive Spinal Cord Stimulation System Receives Breakthrough Device Designation

Jan. 13, 2022 - Wavegate Corporation announced the FDA has granted Breakthrough Device designation for its optical reflectometry system for closed-loop adaptive modulation of spinal cord stimulation. (Source: KPVI)

Startup Closes $10 Million Funding Round

Jan. 11, 2022 - GrayMatters Health announced closure of a $10 million Series A funding round, and plans to apply the funds towards further commercial development of its device for digital self-neuromodulation therapy to support emotional regulation. (Source: Cision)

Noninvasive Neurostimulation Methods Investigated for Long COVID

Jan. 5, 2022 - A news feature discusses recent lines of research into noninvasive neurostimulation as a potential treatment for long COVID. (Source: IEEE Spectrum)

PTSD Treatment Receives Breakthrough Device Designation

Jan. 12, 2022 - The company electroCore, Inc. announced its noninvasive vagus nerve stimulation system received Breakthrough Device designation from the FDA for treatment of post-traumatic stress disorder. (Source: Globe Newswire)

Article Surveys the State of Therapeutic Brain Stimulation Development

Jan. 12, 2022 - A news feature describes research into deep brain stimulation or transcranial magnetic stimulation to potentially treat psychiatric or other conditions. (Source: STAT)

Closed-Loop Spinal Cord Stimulation Two-Year Outcomes Reported

Jan. 8, 2022 - In a secondary analysis, a team of co-authors published two-year outcomes in a randomized controlled trial of closed-loop spinal cord stimulation for chronic back and leg pain. (Source: JAMA Neurology)

Team Unveils a Wearable Noninvasive Brain Stimulation Device

Jan. 7, 2022 - A wearable device its inventors say delivers pulsed magnetic stimulation made a debut at the Consumer Electronics Show, and is being presented as being designed for creation of a meditative state. (Source: Medscape)

Transcranial Direct Current Stimulation Studied in Long COVID

Jan. 7, 2022 - A news feature that references past or future studies discusses neurostimulation as a potential therapy for long COVID. (Source: IFL Science!)

Two-Year Results Published in Clinical Trial of Neurostimulation for Chronic Pain

Jan. 3, 2022 - An article in press presents two-year results in a randomized controlled trial of restorative neurostimulation in patients with chronic disabling back pain secondary to multifidus muscle dysfunction. (Source: Neuromodulation: Technology at the Neural Interface)

Guidelines Published on Spinal Cord Stimulation Surgical Technique

Jan. 1, 2022 - The International Neuromodulation Society’s Neurostimulation Appropriateness Consensus Committee has published recommendations for surgical technique -- including preoperative assessment and postoperative management -- for spinal cord stimulation for the treatment of chronic pain. (Source: Neuromodulation: Technology at the Neural Interface)

International Guidance Published on Cervical Neurostimulation

Jan. 1, 2022 - A multispecialty group of physicians convened by the International Neuromodulation Society, through the  International Neuromodulation Society’s  Neurostimulation Appropriateness Consensus Committee, has published evidence-based guidance on the use of cervical neuromodulation. (Source: Neuromodulation: Technology at the Neural Interface)

Company Announces Expanded MRI Compatibility Approval

Jan. 4, 2022 - Abbott announced that the FDA has approved expanded MRI compatibility labeling of its XR spinal cord stimulation system with Octrode leads. (Source: Mass Device)