Baclofen Infusion

Baclofen (lioresal inthrathecal) is a medication used to manage symptoms and provide relief for patients suffering from spasticity due to multiple sclerosis, stroke, and other conditions. Baclofen infusion is one of the most common uses of neuromodulation infusion devices. For patients whose spasticity has a spinal cord origin, an implantable pump is used if oral baclofen is either ineffective or causes intolerable side effects. Patients whose spasticity is due to traumatic brain injury should wait at least a year before considering long-term intrathecal baclofen therapy.


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Slow infusion of drug or combination of drugs act on the spinal cord receptors both at local level and after diffusion at higher levels . . .


Reviewed March 4, 2012
Lawrence Poree, MD, PhD
Member, International Neuromodulation Society
Professor, University of California School of Medicine, Department of Anesthesia, San Francisco CA, USA

Last Updated on Monday, November 22, 2021 11:03 AM