The International Neuromodulation Society

The Fastest-Growing, Worldwide Multidisciplinary Body Devoted to Building Knowledge of Neuromodulation

The International Neuromodulation Society (INS) is a non-profit group of clinicians, scientists and engineers dedicated to the scientific development and awareness of neuromodulation – the alteration of nerve activity through targeted delivery of a stimulus, such as electrical stimulation or chemical agents, to specific neurological sites in the body. The San Francisco-based INS was formed in 1989 and educates and promotes the field through meetings, its peer-reviewed journal Neuromodulation: Technology at the Neural Interface, mentorship, and chapter websites. The INS also provides information for patients and produces rolling news briefs about this rapidly evolving field.

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The INS Peer-Reviewed Journal

The INS journal Neuromodulation: Technology at the Neural Interface has a growing Impact Factor and is indexed in Index Medicus, MEDLINE and Pubmed from its first issue in 1998. Members may log in to the members-only section to read the journal online. The journal also has social media accounts on Twitter, Facebook, and Instagram.

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What is Neuromodulation?

Medical Professionals can learn about various considerations concerning neuromodulation and clinic contacts. Once your preliminary questions have been answered, please use the Contact Us facility to find out more and to discuss specific objectives. Others may simply wish to join the INS and one of its related chapter societies, please use the Membership Application.

Clinical trials that involve a wide range of emerging neuromodulation approaches are listed on our Research page. Neuromodulation clinical trials address symptom control through nerve stimulation in such condition categories as:

Chronic pain
Movement disorders
Epilepsy
Psychiatric disorders
Stroke / brain injury
Cardiovascular disorders
Gastrointestinal disorders
Genitourinary and colorectal disorders
Sensory deficits


If you are not a medical professional
and you are searching for information about neuromodulation and how these types of treatment could benefit a specific condition such as treatment-resistant headache or other chronic pain syndromes, you may find the sections titled Therapies, About Neuromodulation or FAQs particularly helpful.

Members may log in and visit the members-only section’s Global Discussion Forum

Breaking News

Study Indicates rTMS Treatments Alter Neural Connectivity Brain-Wide in Treatment-Resistant Depressed Patients 

Mar. 16, 2023 - An American Journal of Psychiatry study of treatment-resistant depressed patients reported widespread acute alterations in functional connectivity beyond the targeted cortical area after one rTMS (repetitive transcranial magnetic stimulation) session. Patients with the most pronounced connectivity changes in session one tended to get more benefit from a 4-week course of therapy. (Source: Brain & Behavior Research Foundation)

Depression Severity was Decoded from Intracranial Neural Activity in a Recent Study

Mar. 16, 2023 - In a study published in Biological Psychiatry, intracranial electrodes were implanted in the prefrontal cortical regions in three human subjects with severe depression and depression severity scores were taken from neural recordings. Reduced depression severity was associated with decreased low-frequency neural activity and increased high-frequency activity. (Source: Neuroscience News)

Study Explored Relationship Between ECAP Thresholds and Behavioral T-levels in Implanted Children with Cochlear Nerve Deficiency 

Mar. 15, 2023 - A study of 29 children diagnosed with cochlear nerve deficiency (CND) who underwent cochlear implantation found a significant correlation between electrically evoked compound action potential (ECAP) thresholds and behavioral-T levels. The results can more efficiently inform the selection of stimulation levels for children who cannot cooperate with behavioral testing. (Source: Scientific Reports) 

Neurostimulation and Neuromodulation Offer New Approaches to Treat Dry Eye

Mar. 7, 2023 - Devices and pharmaceuticals that stimulate the trigeminal nerve have been found to produce real tears that provide relief for ocular surface disease. (Source: Healio)

Company’s FDA Clearance is Expanded for Neuromodulation Armband for Migraine

Mar. 1, 2023 - The Nerivio neuromodulation armband is available by prescription to treat migraine symptoms after onset, and newly expanded FDA clearance approved the device for migraine prevention. (Source: Fierce Biotech)

Study Details Early Vagus Nerve Mapping and Novel Vagus Nerve Stimulation Device

Feb. 28, 2023 - Researchers at the Feinstein Institutes for Medical Research published findings in the journal Brain Stimulation after microscopically mapping more than 100,000 fibers that comprise the vagus nerve. The study addresses how they are connected and what bodily functions they control, and insight into a vagus nerve stimulation (VNS) device that can actively target these fibers. (Source: Neuronews International)

Article Summarizes Spinal Cord Stimulation Study of Stroke Patients with Upper-Limb Paresis

Feb. 20, 2023 - NPR summarizes the publication of a four-week study in Nature Medicine which reports that cervical spinal cord stimulation improved arm and hand movement for two participants with limb paresis years after stroke. The article features the experience of one study participant and the medical team who conducted the study. (Source: NPR)

First-Person Article Details Impact of Deep Brain Stimulation for Parkinson’s

Feb. 20, 2023 -  CBC News New Brunswick host Harry Forestell addresses how deep brain stimulation (DBS) can improve motor function control in some Parkinson’s patients and shares his first-person experience with the procedure, along with a video that demonstrates its effects. (Source: CBC News)

News Column Addresses Bioelectricity and Numerous Applications in Neuromodulation 

Feb. 5, 2023 -  A column about bioelectricity describes transcranial direct current stimulation (tDCS), deep-brain stimulation (DBS), and other potential therapeutic and elective implications of bioelectricity in neuromodulation. (Source: The Guardian)

Video Features Deep Brain Stimulation Patients for Movement Disorders

Feb. 5, 2023 - 60 Minutes Australia featured patients with Parkinson’s and essential tremor (ET) before and after their experience receiving deep brain stimulation (DBS), and addressed the procedure’s potential benefit for a range of movement disorders and other conditions. (Source: 60 Minutes Australia)

To see select neuromodulation news by category, as well as news about the INS in particular, please visit the Newsroom. To see archived news briefs dating back to January 2011, visit the News Archive.

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