The International Neuromodulation SocietyThe Fastest-Growing, Worldwide Multidisciplinary Body Devoted to Building Knowledge of NeuromodulationThe International Neuromodulation Society (INS) is a non-profit group of clinicians, scientists and engineers dedicated to the scientific development and awareness of neuromodulation – the alteration of nerve activity through targeted delivery of a stimulus, such as electrical stimulation or chemical agents, to specific neurological sites in the body. The San Francisco-based INS was formed in 1989 and educates and promotes the field through meetings, its peer-reviewed journal Neuromodulation: Technology at the Neural Interface, mentorship, and chapter websites. The INS also provides information for patients and produces rolling news briefs about this rapidly evolving field. Donate TodayThe INS Peer-Reviewed JournalThe INS journal Neuromodulation: Technology at the Neural Interface has a growing Impact Factor and is indexed in Index Medicus, MEDLINE and Pubmed from its first issue in 1998. Members may log in to the members-only section to read the journal online. The journal also has social media accounts on Twitter, Facebook, and Instagram.
The Neuromodulation Podcast has been developed for our membership to dive into the forefront of today's emerging neuromodulation techniques, insights, and ethical and clinical applications. Join the multidisciplinary collaboration of medical care providers, scientists, and engineers who are part of the global conversation that's shaping the future of healthcare. Subscribe now wherever you get your podcasts. What is Neuromodulation?Medical Professionals can learn about various considerations concerning neuromodulation and clinic contacts. Once your preliminary questions have been answered, please use the Contact Us facility to find out more and to discuss specific objectives. Others may simply wish to join the INS and one of its related chapter societies, please use the Membership Application. Clinical trials that involve a wide range of emerging neuromodulation approaches are listed on our Research page. Neuromodulation clinical trials address symptom control through nerve stimulation in such condition categories as:
Breaking NewsClinical Study Shows Promise for VNS-Enhanced PTSD Treatment May 6, 2025 - A pioneering clinical trial led by UT Dallas and Baylor University Medical Center found that pairing vagus nerve stimulation (VNS) with prolonged exposure therapy eliminated PTSD diagnoses in all nine participants six months post-treatment. The study suggests VNS may enhance therapy outcomes by boosting neuroplasticity and sustaining remission. A Phase 2 trial is currently underway to validate the findings. (Source: Neuroscience News) Study Shows Speech Cortex BCI Can Enable Computer Control and Communication for ALS Patients May 2, 2025 - Researchers from University of California, Davis have developed a brain-computer interface (BCI) that allows computer cursor control and click by using neuron signals from the speech motor cortex. In a case study, a participant with amyotrophic lateral sclerosis (ALS) used the system to navigate a desktop computer, select on-screen targets with 93% accuracy, and type independently. (Source: Medical Xpress) Focused Ultrasound Eases Symptoms of Depression, Anxiety, and PTSD April 29, 2025 - New research from the University of Texas found that low-intensity focused ultrasound can safely target the amygdala and significantly reduce symptoms of depression, anxiety, and PTSD after three weeks of daily, noninvasive sessions. The treatment directly modulates deep brain activity without surgery or medication and showed a safety profile, supporting its potential for treatment-resistant mood disorders. (Source: Neuroscience News) Study Links rTMS to Brain Connectivity and Gene Expression in Depression April 24, 2025 - A study published in Translational Psychiatry found that high-frequency repetitive transcranial magnetic stimulation (rTMS) in patients with major depressive disorder increased brain connectivity in key regions and was linked to genes involved in neural plasticity and synaptic function. These results indicate that rTMS may alleviate depression by modulating both brain networks and related gene expression. (Source: Springer Nature) Diffusion MRI Biomarkers Forecast Motor Improvement Post-STN-DBS in Parkinson’s April 21, 2025 - A prospective, open-label study found that preserved brain microstructure, as assessed by diffusion MRI, was associated with better motor outcomes following subthalamic nucleus deep brain stimulation (STN-DBS) in patients with Parkinson’s disease. The findings suggest that neuroimaging biomarkers could enhance preoperative counseling and help predict which patients are most likely to benefit from the intervention. (Source: Springer Nature) Study Links Brain Stimulation to Cognitive Flexibility April 15, 2025 - A study from Martin Luther University Halle-Wittenberg found that transcranial direct current stimulation (tDCS) can subtly influence decision-making speed and flexibility by targeting the dorsolateral prefrontal cortex. Anodal stimulation led to quicker decisions, while cathodal stimulation reduced cognitive flexibility, highlighting tDCS’s potential to modulate cognitive processes under controlled conditions. (Source: Neuroscience News) To see select neuromodulation news by category, as well as news about the INS in particular, please visit the Newsroom. To see archived news briefs dating back to January 2011, visit the News Archive. Continue Reading News Briefs |
