The International Neuromodulation Society

The Fastest-Growing, Worldwide Multidisciplinary Body Devoted to Building Knowledge of Neuromodulation

The International Neuromodulation Society (INS) is a non-profit group of clinicians, scientists and engineers dedicated to the scientific development and awareness of neuromodulation – the alteration of nerve activity through targeted delivery of a stimulus, such as electrical stimulation or chemical agents, to specific neurological sites in the body. The San Francisco-based INS was formed in 1989 and educates and promotes the field through meetings, its peer-reviewed journal Neuromodulation: Technology at the Neural Interface, mentorship, and chapter websites. The INS also provides information for patients and produces rolling news briefs about this rapidly evolving field.

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The INS Peer-Reviewed Journal

The INS journal Neuromodulation: Technology at the Neural Interface has a growing Impact Factor and is indexed in Index Medicus, MEDLINE and Pubmed from its first issue in 1998. Members may log in to the members-only section to read the journal online. The journal also has social media accounts on Twitter, Facebook, and Instagram.

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The Neuromodulation Podcast has been developed for our membership to dive into the forefront of today's emerging neuromodulation techniques, insights, and ethical and clinical applications.

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What is Neuromodulation?

Medical Professionals can learn about various considerations concerning neuromodulation and clinic contacts. Once your preliminary questions have been answered, please use the Contact Us facility to find out more and to discuss specific objectives. Others may simply wish to join the INS and one of its related chapter societies, please use the Membership Application.

Clinical trials that involve a wide range of emerging neuromodulation approaches are listed on our Research page. Neuromodulation clinical trials address symptom control through nerve stimulation in such condition categories as:

Chronic pain
Movement disorders
Epilepsy
Psychiatric disorders
Brain injury / Stroke 
Cardiovascular disorders
Gastrointestinal disorders
Genitourinary and colorectal disorders
Sensory deficits


If you are not a medical professional
and you are searching for information about neuromodulation and how these types of treatment could benefit a specific condition such as treatment-resistant headache or other chronic pain syndromes, you may find the sections titled Therapies, About Neuromodulation or FAQs particularly helpful.

Breaking News

Targeted Brain Stimulation Shows Promise for Treating Depression

October 6, 2025 - A UCLA study found that a 12-day course of high-definition transcranial direct current stimulation (HD-tDCS) significantly improved mood in adults with moderate to severe depression compared with a sham treatment. The noninvasive therapy, which delivers focused electrical stimulation to specific brain regions, was well tolerated with mild side effects. (Source: Healio)

September 26, 2025 - Washington University in St. Louis researchers received a nearly $3 million National Institutes of Health grant to investigate how personalized transcutaneous spinal cord stimulation can enhance movement in people with spinal cord injuries. The five-year study will explore how varying stimulation parameters affect muscle activation and leg control in 48 participants with partial motor function. (Source: Becker's Spine Review)

FDA Clears Tibial Nerve Stimulation Device for Urge Urinary Incontinence

September 22, 2025 - The FDA has approved a neuromodulation device that is implanted near the ankle to deliver electrical impulses to the tibial nerve, helping regulate bladder control in patients with urge urinary incontinence. The therapy provides a less invasive alternative to sacral nerve stimulation and enters a market with other tibial devices already available. (MedTech Dive)

Long-Term Adaptive DBS Found Safe and Effective in Parkinson’s Disease

September 22, 2025 - An international clinical trial evaluated long-term adaptive deep brain stimulation (aDBS) in people with Parkinson’s disease who were stable on continuous DBS (cDBS). Results showed that aDBS was well tolerated and provided effective symptom control comparable to cDBS, with reduced energy use in some cases. These findings suggest aDBS may offer a viable alternative for long-term therapy. (Source: JAMA Neurology)

FDA Approves Vagus Nerve Stimulation Device for Rheumatoid Arthritis

September 22, 2025 - The FDA has approved an implantable vagus nerve stimulation device for patients with rheumatoid arthritis whose symptoms are not adequately controlled by medication. The device delivers mild electrical pulses that regulate inflammation and has shown meaningful improvement in clinical trials, with some patients experiencing significant symptom relief. Researchers suggest the approach could also hold promise for other autoimmune conditions. (Source: NPR)

Implant Stabilizes Blood Pressure After Spinal Cord Injury

September 22, 2025 - Researchers have developed an implantable neurostimulation system that restores stable blood pressure in people with spinal cord injuries. Clinical trials across several countries showed rapid normalization of blood pressure, reducing dangerous drops and spikes. The findings offer a potential new approach to improving quality of life and reducing cardiovascular risks in patients. (Source: Education News Canada)

To see select neuromodulation news by category, as well as news about the INS in particular, please visit the Newsroom. To see archived news briefs dating back to January 2011, visit the News Archive.

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