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Intrathecal or Intraspinal Drug DeliveryIn intrathecal drug delivery, pain medication is introduced directly to the spinal fluid through a pump and catheter. With this method, less medication is necessary than if medication were taken orally, and fewer side effects are seen. New intrathecal drugs such as ziconotide are highly effective at reducing pain, and can only be given intrathecally. Direct delivery of agents intrathecally bypasses the first pass effect of agents that are delivered orally and diffuse into the substance of the spinal cord where they work . . . |
